The effect of probucol on low density lipoprotein oxidation and femoral atherosclerosis

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

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Beyond Cholesterol

1989 • 6,533 citations

The Effect of Vitamin E and Beta Carotene on the Incidence of Lung Cancer and Other Cancers in Male Smokers

1994 • 4,626 citations

A new method for the direct determination of serum cholesterol.

1953 • 2,530 citations

Vitamin E Consumption and the Risk of Coronary Heart Disease in Men

1993 • 2,363 citations

Vitamin E Consumption and the Risk of Coronary Disease in Women

1993 • 2,158 citations

A simple fluorometric assay for lipoperoxide in blood plasma

1976 • 2,101 citations

Continuous Monitoring ofin VztroOxidation of Human Low Density Lipoprotein

1989 • 1,824 citations

Autoantibody against oxidised LDL and progression of carotid atherosclerosis

1992 • 1,332 citations

Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis.

1987 • 1,152 citations

A colorimetric method for estimating serum triglycerides

1968 • 1,137 citations

The Effect of Cholesterol-Lowering and Antioxidant Therapy on Endothelium-Dependent Coronary Vasomotion

1995 • 1,123 citations

Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit.

1987 • 1,051 citations

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.

1981 • 1,037 citations

Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia.

1987 • 885 citations

Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins

1990 • 871 citations

High-density lipoprotein inhibits the oxidative modification of low-density lipoprotein

1990 • 836 citations

Susceptibility to low-density lipoprotein oxidation and coronary atherosclerosis in man

1992 • 588 citations

Lipoprotein oxidation and lipoprotein-induced cytotoxicity.

1983 • 545 citations

Regulation of the activity of the low density lipoprotein receptor in human fibroblasts

1975 • 477 citations

High density lipoprotein is the major carrier of lipid hydroperoxides in human blood plasma from fasting donors.

1992 • 471 citations

Enhanced macrophage degradation of biologically modified low density lipoprotein.

1983 • 469 citations

Lipoprotein fractionation.

1973 • 420 citations

HDL, its enzymes and its potential to influence lipid peroxidation

1995 • 416 citations

Labelling of plasma proteins with radioactive iodine

1956 • 379 citations

Supplementation with vitamin E but not beta-carotene in vivo protects low density lipoprotein from lipid peroxidation in vitro. Effect of cigarette smoking.

1992 • 354 citations

Oxidized low density lipoprotein induces differentiation and adhesion of human monocytes and the monocytic cell line U937.

1990 • 335 citations

α-tocopherol consumption during low-density-lipoprotein oxidation

1990 • 312 citations

The effect of probucol on femoral atherosclerosis: The Probucol Quantitative Regression Swedish Trial (PQRST)

1994 • 251 citations

Effects of probucol on xanthomata regression in familial hypercholesterolemia

1986 • 232 citations

Minimally oxidized low-density lipoprotein induces tissue factor expression in cultured human endothelial cells.

1991 • 228 citations

β-Carotene inhibits the oxidative modification of low-density lipoprotein

1991 • 227 citations

Inhibition of hypercholesterolemia-induced atherosclerosis in the nonhuman primate by probucol. I. Is the extent of atherosclerosis related to resistance of LDL to oxidation?

1994 • 224 citations

Platelet activation by oxidatively modified low density lipoproteins

1989 • 183 citations

Biologically modified LDL increases the adhesive properties of endothelial cells

1991 • 179 citations

Native and oxidized LDL enhances production of PDGF AA and the surface expression of PDGF receptors in cultured human smooth muscle cells.

1992 • 169 citations

Probucol

1989 • 161 citations

Vitamin E content and low density lipoprotein oxidizability induced by free radicals

1990 • 137 citations

Effects of probucol on homozygous cases of familial hypercholesterolemia

1983 • 113 citations

Stimulating effect of oxidized low density lipoproteins on plasminogen activator inhibitor-1 synthesis by endothelial cells.

1991 • 110 citations

Predisposition to LDL oxidation in patients with and without angiographically established coronary artery disease

1993 • 109 citations

Oxidative status of lipoproteins in coronary disease patients

1992 • 102 citations

Supplementation with Vitamin E but Not Beta-Carotene in Vivo Protects Low Density Lipoprotein from Lipid Peroxidation in Vitro

1992 • 99 citations

The effects of probucol on the progression of atherosclerosis in mature Watanabe heritable hyperlipidaemic rabbits

1991 • 93 citations

Effect of probucol dosage on plasma lipid and lipoprotein levels and on protection of low density lipoprotein against in vitro oxidation in humans.

1992 • 87 citations

Lowering of HDL _2b by Probucol Partly Explains the Failure of the Drug to Affect Femoral Atherosclerosis in Subjects With Hypercholesterolemia

1995 • 81 citations

Effect of probucol treatment on the susceptibility of low density lipoprotein isolated from hypercholesterolemic patients to become oxidatively modified in vitro

1990 • 62 citations

Development of femoral atherosclerosis in hypercholesterolemic patients during treatment with cholestyramine and probucol/placebo: Probucol quantitative regression Swedish trial (PQRST): A status report

1988 • 61 citations

Simultaneous measurement of serum probucol and lipid-soluble antioxidants.

1992 • 55 citations

Probucol Treatment Decreases Serum Concentrations of Diet-Derived Antioxidants

1995 • 53 citations

Antiatherosclerotic effects of antioxidants are lesion-specific when evaluated in hypercholesterolemic New Zealand White rabbits

1992 • 45 citations

Recirculation of cationized ferritin in cultured mouse peritoneal macrophages. Electron microscopic and cytochemical studies with double-labeling technique.

1980 • 31 citations

Changes in atheroma volume estimated from digitized femoral arteriograms

1990 • 22 citations

Influence of lipoprotein lipids, dietary fat and smoking on macrophage degradation of native and oxidized low density lipoprotein

1994 • 9 citations

Changes in atheroma volume estimated from digitized femoral arteriograms

1990 • 8 citations

Repeat femoral arteriography in hyperlipidemic patients

1988 • 2 citations