The effects of probucol on the progression of atherosclerosis in mature Watanabe heritable hyperlipidaemic rabbits

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

1955 • 8,846 citations

Beyond Cholesterol

1989 • 6,533 citations

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.

1984 • 1,631 citations

Low density lipoprotein undergoes oxidative modification in vivo.

1989 • 1,537 citations

Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method

1979 • 1,477 citations

A specific method for the analysis of hydroxyproline in tissues and urine

1960 • 1,065 citations

Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit.

1987 • 1,051 citations

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.

1981 • 1,037 citations

Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia.

1987 • 885 citations

Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages

1980 • 851 citations

Malondialdehyde-Altered Protein Occurs in Atheroma of Watanabe Heritable Hyperlipidemic Rabbits

1988 • 757 citations

Probucol inhibits oxidative modification of low density lipoprotein.

1986 • 633 citations

Arterial foam cells with distinctive immunomorphologic and histochemical features of macrophages.

1980 • 475 citations

Macrophage oxidation of low density lipoprotein generates a modified form recognized by the scavenger receptor.

1986 • 417 citations

Presence of a modified low density lipoprotein in humans.

1988 • 373 citations

Fatty streak initiation in Watanabe Heritable Hyperlipemic and comparably hypercholesterolemic fat-fed rabbits.

1987 • 337 citations

Characterization of lipid-laden aortic cells from cholesterol-fed rabbits. IV. Investigation of macrophage-like properties of aortic cell populations.

1979 • 297 citations

Cellular pathology of progressive atherosclerosis in the WHHL rabbit. An animal model of familial hypercholesterolemia.

1983 • 282 citations

Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit.

1989 • 250 citations

Quantitative analysis of cholesterol in 5 to 20 μl of plasma

1974 • 247 citations

Fatty streak expansion and maturation in Watanabe Heritable Hyperlipemic and comparably hypercholesterolemic fat-fed rabbits.

1987 • 174 citations

Probucol

1989 • 161 citations

Probucol attenuates the development of aortic atherosclerosis in cholesterol‐fed rabbits

1989 • 142 citations

Concentration and composition of lipoproteins in blood plasma of the WHHL rabbit. An animal model of human familial hypercholesterolemia.

1982 • 135 citations

Isolation of low density lipoprotein from atherosclerotic vascular tissue of Watanabe heritable hyperlipidemic rabbits.

1988 • 135 citations

A novel mechanism by which probucol lowers low density lipoprotein levels demonstrated in the LDL receptor-deficient rabbit.

1984 • 127 citations

Effects of probucol on homozygous cases of familial hypercholesterolemia

1983 • 113 citations

Concentration-dependent antioxidant activity of probucol in low density lipoproteins in vitro: probucol degradation precedes lipoprotein oxidation.

1989 • 107 citations

Lack of effect of probucol on atheroma formation in cholesterol-fed rabbits kept at comparable plasma cholesterol levels

1989 • 102 citations

Effect of probucol on the physical properties of low-density lipoproteins oxidized by copper

1989 • 90 citations

Studies on the mechanism of action of probucol

1986 • 76 citations

Probucol prevents lipid storage in macrophages

1986 • 69 citations

Effect of probucol on macrophages, leading to regression of xanthomas and atheromatous vascular lesions

1988 • 62 citations

Influence of 4,4'-(Isopropylidenedithio)bis(2,6-di-t-butylphenol) (DH-581) on Experimental Atherosclerosis in Rabbits

1971 • 51 citations

Combined effects of cholestyramine and probucol on regression of atherosclerosis in rhesus monkey aortas.

1983 • 51 citations

Effect of Probucol, Pantethine and Their Combinations on Serum Lipoprotein Metabolism and on the Incidence of Atheromatous Lesions in the Rabbit

1986 • 44 citations

Comparison of gas chromatography and high-performance liquid chromatography for the analysis of probucol in plasma

1986 • 42 citations

Probucol does not alter acetylated low density lipoprotein uptake by murine peritoneal macrophages

1990 • 9 citations