Exercise, cognition, and the aging brain

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

1999 • 3,805 citations

Fitness Effects on the Cognitive Function of Older Adults

2003 • 3,561 citations

Regional Brain Changes in Aging Healthy Adults: General Trends, Individual Differences and Modifiers

2005 • 2,727 citations

Exercise: a behavioral intervention to enhance brain health and plasticity

2002 • 2,571 citations

Insights into the ageing mind: a view from cognitive neuroscience

2004 • 2,112 citations

Exercise Enhances Learning and Hippocampal Neurogenesis in Aged Mice

2005 • 2,005 citations

Cardiovascular fitness, cortical plasticity, and aging

2004 • 1,612 citations

Exercise Is Associated with Reduced Risk for Incident Dementia among Persons 65 Years of Age and Older

2006 • 1,444 citations

The effects of exercise training on elderly persons with cognitive impairment and dementia: A meta-analysis11No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.

2004 • 1,206 citations

Learning causes synaptogenesis, whereas motor activity causes angiogenesis, in cerebellar cortex of adult rats.

1990 • 1,142 citations

Physical Activity, Including Walking, and Cognitive Function in Older Women

2004 • 1,133 citations

Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease

2005 • 1,043 citations

Circulating Insulin-Like Growth Factor I Mediates Exercise-Induced Increases in the Number of New Neurons in the Adult Hippocampus

2001 • 976 citations

A Prospective Study of Physical Activity and Cognitive Decline in Elderly Women

2001 • 894 citations

Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male sprague–dawley rats in vivo

2004 • 816 citations

Physical Activity, APOE Genotype, and Dementia Risk: Findings from the Cardiovascular Health Cognition Study

2005 • 661 citations

Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin 3.

1991 • 610 citations

A Longitudinal Study of Cardiorespiratory Fitness and Cognitive Function in Healthy Older Adults

2003 • 598 citations

Circulating Insulin-Like Growth Factor I Mediates the Protective Effects of Physical Exercise against Brain Insults of Different Etiology and Anatomy

2001 • 593 citations

Lifespan CognitionMechanisms of Change

2006 • 514 citations

Cognitive activity and incident AD in a population-based sample of older persons

2002 • 450 citations

Improvement of Cognitive Function by Mental and/or Individualized Aerobic Training in Healthy Elderly Subjects

2002 • 407 citations

After Reaching Retirement Age Physical Activity Sustains Cerebral Perfusion and Cognition

1990 • 369 citations

Estrogen and exercise interact to regulate brain‐derived neurotrophic factor mRNA and protein expression in the hippocampus

2001 • 324 citations

Regulation of late-phase LTP and long-term memory in normal and aging hippocampus: role of secreted proteins tPA and BDNF

2004 • 318 citations

Exercise increases hippocampal neurogenesis to high levels but does not improve spatial learning in mice bred for increased voluntary wheel running.

2003 • 269 citations

Spatial learning and physical activity contribute to the induction of fibroblast growth factor: neural substrates for increased cognition associated with exercise

1998 • 267 citations

The exercise-induced expression of BDNF within the hippocampus varies across life-span

2005 • 256 citations

Physical activity enhances spatial learning performance with an associated alteration in hippocampal protein kinase C activity in C57BL/6 and DBA/2 mice

1993 • 255 citations

Association Between Dementia and Midlife Risk Factors: the Radiation Effects Research Foundation Adult Health Study

2003 • 243 citations

Early Life Physical Activity and Cognition at Old Age

2003 • 236 citations

Effect of sustained exercise on plasma amino acid concentrations and on 5‐hydroxytryptamine metabolism in six different brain regions in the rat

1989 • 219 citations

Can the brain be protected through exercise? Lessons from an animal model of parkinsonism☆

2003 • 206 citations

Interactive effects of fitness and hormone treatment on brain health in postmenopausal women

2006 • 146 citations

Enhancement of spatial learning in F344 rats by physical activity and related learning-associated alterations in hippocampal and cortical cholinergic functioning

1991 • 143 citations

Exercise, antidepressant treatment, and BDNF mRNA expression in the aging brain

2003 • 131 citations

Hippocampal brain‐derived neurotrophic factor gene regulation by exercise and the medial septum

2002 • 131 citations

Mild forced treadmill exercise enhances spatial learning in the aged rat

2006 • 129 citations

Age-dependence of the effect of treadmill exercise on cell proliferation in the dentate gyrus of rats

2003 • 110 citations

Normal Genetic Variation, Cognition, and Aging

2003 • 108 citations

Treadmill training ameliorates dopamine loss but not behavioral deficits in hemi-Parkinsonian rats

2005 • 105 citations

The Aging of Executive Functions

2006 • 67 citations

Evaluation of quality of life in elderly healthy subjects after aerobic and/or mental training

1999 • 49 citations

The concise Columbia dictionary of quotations

1989 • 10 citations

Cassell's humorous quotations

2002 • 4 citations