A Defect in Interleukin 12–Induced Activation and Interferon γ Secretion of Peripheral Natural Killer T Cells in Nonobese Diabetic Mice Suggests New Pathogenic Mechanisms for Insulin-Dependent Diabetes Mellitus

Requirement for V _α 14 NKT Cells in IL-12-Mediated Rejection of Tumors

1997 • 1,226 citations

Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).

1996 • 985 citations

CD1 Recognition by Mouse NK1 ⁺ T Lymphocytes

1995 • 903 citations

CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3.

1994 • 862 citations

CD1d-mediated Recognition of an α-Galactosylceramide by Natural Killer T Cells Is Highly Conserved through Mammalian Evolution

1998 • 649 citations

Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes

1998 • 642 citations

CD1d1 Mutant Mice Are Deficient in Natural T Cells That PromptlyProduce IL-4

1997 • 612 citations

Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes.

1995 • 517 citations

Role of NK1.1 ⁺ T Cells in a T _H 2 Response and in Immunoglobulin E Production

1995 • 508 citations

Impaired NK1+ T Cell Development and Early IL-4 Production in CD1-Deficient Mice

1997 • 494 citations

Interferon‐γ confers resistance to experimental allergic encephalomyelitis

1996 • 478 citations

α/β–T Cell Receptor (TCR)+CD4−CD8− (NKT) Thymocytes Prevent Insulin-dependent Diabetes Mellitus in Nonobese Diabetic (NOD)/Lt Mice by the Influence of Interleukin (IL)-4 and/or IL-10

1998 • 473 citations

CD1d-restricted Recognition of Synthetic Glycolipid Antigens by Human Natural Killer T Cells

1998 • 445 citations

Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice.

1995 • 428 citations

Overexpression of Natural Killer T Cells Protects Vα14-Jα281 Transgenic Nonobese Diabetic Mice against Diabetes

1998 • 390 citations

Interferon gamma plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance.

1990 • 372 citations

Regulation of Experimental Autoimmune Encephalomyelitis by Natural Killer (NK) Cells

1997 • 360 citations

Early quantitative and functional deficiency of NK1⁺‐like thymocytes in the NOD mouse

1996 • 359 citations

NK1.1+ T cell receptor-alpha/beta+ cells: new clues to their origin, specificity, and function.

1995 • 355 citations

Interferon gamma production by natural killer (NK) cells and NK1.1+ T cells upon NKR-P1 cross-linking.

1996 • 349 citations

Cultured NK1.1+ CD4+ T cells produce large amounts of IL-4 and IFN-gamma upon activation by anti-CD3 or CD1.

1997 • 291 citations

Selective reduction of V alpha 14+ NK T cells associated with disease development in autoimmune-prone mice.

1996 • 290 citations

Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells.

1996 • 268 citations

Association Between αβTCR+CD4−CD8− T-Cell Deficiency and IDDM in NOD/Lt Mice

1997 • 258 citations

Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4.

1995 • 237 citations

Mouse NK1.1+ T cells: a new family of T cells

1996 • 236 citations

Rapid Death and Regeneration of NKT Cells in Anti-CD3ε- or IL-12-Treated Mice

1998 • 233 citations

Cytotoxic NK1.1 Ag+ alpha beta T cells with intermediate TCR induced in the liver of mice by IL-12.

1995 • 222 citations

Critical role of NK1+ T cells in IL-12-induced immune responses in vivo.

1998 • 179 citations

The CD1 family of lipid antigen-presenting molecules

1998 • 171 citations

Class I dependence of the development of CD4+ CD8- NK1.1+ thymocytes.

1994 • 155 citations

A role for CD4+ NK1.1+ T lymphocytes as major histocompatibility complex class II independent helper cells in the generation of CD8+ effector function against intracellular infection.

1996 • 154 citations

Cytotoxicity of fresh NK1.1+ T cell receptor alpha/beta+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target.

1994 • 144 citations

Chronic relapsing experimental autoimmune encephalomyelitis (CREAE) in mice: enhancement by monoclonal antibodies against interferon‐γ

1996 • 141 citations

Cutting Edge: Critical Role of NK1+ T Cells in IL-12-Induced Immune Responses In Vivo

1998 • 136 citations

LPS induces NK1.1+ alpha beta T cells with potent cytotoxicity in the liver of mice via production of IL-12 from Kupffer cells.

1996 • 132 citations

Beta 2-microglobulin-dependent T cells are dispensable for allergen-induced T helper 2 responses.

1996 • 103 citations

IL-4-producing NK T cells are biased towards IFN-γ production by IL-12. Influence of the microenvironment on the functional capacities of NK T cells

1998 • 93 citations

Positive selection of invariant V alpha 14+ T cells by non-major histocompatibility complex-encoded class I-like molecules expressed on bone marrow-derived cells.

1995 • 84 citations

Induction or Protection from Experimental Autoimmune Encephalomyelitis Depends on the Cytokine Secretion Profile of TCR Peptide-Specific Regulatory CD4 T Cells

1998 • 81 citations

Immunosuppressive activity of cloned natural killer (NK1.1+) T cells established from murine tumor-infiltrating lymphocytes.

1997 • 70 citations

IL-7 reverses NK1⁺ Tcell-defective IL-4 production in the non-obese diabetic mouse

1996 • 69 citations

Development of CD4-CD8- alpha beta TCR+NK1.1+ T lymphocytes: thymic selection by self antigen.

1996 • 54 citations

Autologous killing by a population of intermediate T‐cell receptor cells and its NK1.1⁺ and NK1.1⁻ subsets, using Fas ligand/Fas molecules

1997 • 49 citations

Lymphokine-activated killer cell activity of CD4-CD8- TCR alpha beta + thymocytes.

1993 • 43 citations

Natural suppressor activity in graft-vs-host spleen and normal bone marrow is augmented by IL 2 and interferon-gamma.

1986 • 42 citations

Involvement of IFN-gamma and transforming growth factor-beta in graft-vs-host reaction-associated immunosuppression.

1993 • 41 citations

Interleukin‐12 induces cytotoxic NK1⁺αβ T cells in the lungs of euthymic and athymic mice

1996 • 37 citations

EVIDENCE THAT IFN-7 IS RESPONSIBLE FOR NATURAL SUPPRESSOR ACTIVITY IN GVHD SPLEEN AND NORMAL BONE MARROW

1988 • 32 citations

TCR-mediated target cell lysis by CD4+NK1+ liver T lymphocytes

1997 • 23 citations

Rat NKR‐P1⁺ CD3⁺ T cells: selective proliferation in interleukin‐2, diverse T‐cell‐receptor‐Vβ repertoire and polarized interferon‐γ expression

1998 • 12 citations

Intermediate TCR Cells Can Induce Graft-versus-Host Disease after Allogeneic Bone Marrow Transplantation

1998 • 12 citations

Involvement of both donor cytotoxic T lymphocytes and host NK1.1⁺ T cells in the thymic atrophy of mice suffering from acute graft‐versus‐host disease

1998 • 9 citations

The emergence of non‐cytolytic NK1.1⁺ T cells in the long‐term culture of murine tumour‐infiltrating lymphocytes: a possible role of transforming growth factor‐β

1996 • 6 citations

Participation of NK1.1⁺ T Cells in the Rejection of lpr αβT Cells When Bone Marrow Cells of Ipr Mice Are Transplanted into B6 Mice

1998 • 5 citations

β2-Microglobulin-Dependent T Cells Are Not Necessary for Alloantigen-Induced Th2 Responses After Neonatal Induction of Lymphoid Chimerism in Mice

1998 • 3 citations

Beta 2-microglobulin-dependent T cells are not necessary for alloantigen-induced Th2 responses after neonatal induction of lymphoid chimerism in mice.

1998 • 3 citations

Deleted Work

1955 • 0 citations