Ligation of Endothelial α _v β ₃ Integrin Increases Capillary Hydraulic Conductivity of Rat Lung

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

1987 • 3,773 citations

Requirement of Vascular Integrin α _v β ₃ for Angiogenesis

1994 • 3,016 citations

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

1994 • 2,293 citations

Signal transduction from the extracellular matrix.

1993 • 1,727 citations

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.

1992 • 1,330 citations

The Lung: Scientific Foundations

1991 • 1,181 citations

Synergistic Roles for Receptor Occupancy and Aggregation in Integrin Transmembrane Function

1995 • 900 citations

Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins.

1991 • 713 citations

Novel purification of vitronectin from human plasma by heparin affinity chromatography.

1988 • 525 citations

Structure and Biological Role of Vitronectin

1991 • 477 citations

T Cell Antigen Receptor-Mediated Activation of Phospholipase C Requires Tyrosine Phosphorylation

1990 • 476 citations

Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape.

1991 • 368 citations

Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface.

1991 • 357 citations

The role of integrins in the maintenance of endothelial monolayer integrity.

1991 • 290 citations

Integrin-ligarid interactions: a year in review

1994 • 282 citations

Increased endothelial albumin permeability mediated by protein kinase C activation.

1990 • 271 citations

Tyrosine phosphorylation and cytoskeletal reorganization in platelets are triggered by interaction of integrin receptors with their immobilized ligands

1993 • 260 citations

Spreading of human endothelial cells on fibronectin or vitronectin triggers elevation of intracellular free calcium.

1993 • 242 citations

Role of platelet membrane glycoprotein IIb-IIIa in agonist-induced tyrosine phosphorylation of platelet proteins.

1990 • 237 citations

Identification and characterization of cell-substratum adhesion receptors on cultured human endothelial cells.

1989 • 186 citations

Tyrosine phosphorylation is involved in receptor coupling to phospholipase D but not phospholipase C in the human neutrophil

1992 • 160 citations

Regulation of permeabilized endothelial cell retraction by myosin phosphorylation

1991 • 149 citations

In vitro formation of disulfide-bonded fibronectin multimers.

1983 • 138 citations

Human endothelial cells express integrin receptors on the luminal aspect of their membrane

1992 • 131 citations

Involvement of tyrosine kinases in the activation of human peripheral blood neutrophils by granulocyte-macrophage colony-stimulating factor

1991 • 105 citations

Spatiotemporal segregation of endothelial cell integrin and nonintegrin extracellular matrix-binding proteins during adhesion events.

1990 • 104 citations

Transendothelial transport of serum albumin: a quantitative immunocytochemical study

1992 • 103 citations

Accentuated Formation of the Terminal C5b-9 Complement Complex in Patient Plasma Precedes Development of the Adult Respiratory Distress Syndrome

1988 • 95 citations

The alpha v beta 5 integrin receptor regulates receptor-mediated endocytosis of vitronectin

1993 • 94 citations

Soluble Ligands of the αvβ4 Integrin Mediate Enhanced Tyrosine Phosphorylation of Multiple Proteins in Adherent Bovine Pulmonary Artery Endothelial Cells

1995 • 71 citations

Erbstatin blocks platelet activating factor‐induced protein‐tyrosine phosphorylation, polyphosphoinositide hydrolysis, protein kinase C activation, serotonin secretion and aggregation of rabbit platelets

1990 • 68 citations

Identification of integrin cell‐substratum adhesion receptors on cultured rat bone cells

1992 • 67 citations

Clustering of vitronectin and RGD peptides on microspheres leads to engagement of integrins on the luminal aspect of endothelial cell membrane

1994 • 62 citations

The complement SC5b-9 complex mediates cell adhesion through a vitronectin receptor.

1990 • 59 citations

Receptor-mediated endocytosis of vitronectin is regulated by its conformational state

1993 • 57 citations

Protein kinase C-dependent effects of 12(S)-HETE on endothelial cell vitronectin receptor and fibronectin receptor.

1993 • 57 citations

SC5b‐7, SC5b‐8 and SC5b‐9 complexes of complement: ultrastructure and localization of the S‐protein (vitronectin) within the macromolecules

1989 • 52 citations

Effect of the tyrosine kinase inhibitor, genistein, on interleukin-1 stimulated PGE2 production in mesangial cells

1990 • 49 citations

Cooperative enhancement of hyaluronic acid synthesis by combined use of IGF-I and EGF, and inhibition by tyrosine kinase inhibitor genistein, in cultured mesothelial cells from rabbit pericardial cavity

1991 • 48 citations

Inhibition of tyrosine protein kinase by synthetic erbstatin analogs.

1987 • 42 citations

Soluble complex of complement increases hydraulic conductivity in single microvessels of rat lung.

1993 • 37 citations

Segmental barrier properties of the pulmonary microvascular bed

1991 • 36 citations

Hydraulic conductivity of lung venules determined by split-drop technique

1988 • 32 citations

An enzyme-linked immunoabsorbent assay for the quantitation of the terminal complement complex from cell membranes or in activated human sera

1986 • 25 citations

Opposing effects of protein tyrosine kinase inhibitors on the monoclonal antibody induced internalization of CD3 and CD4 antigens

1991 • 8 citations

Hemodynamic effects of brief pulmonary hemostasis

1993 • 2 citations