Integrin-ligarid interactions: a year in review

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment

1993 • 2,182 citations

A novel divalent cation-binding site in the a domain of the ?2 integrin CR3 (CD11b/CD18) is essential for ligand binding

1993 • 383 citations

Structure of a major immunogenic site on foot-and-mouth disease virus

1993 • 361 citations

The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence.

1993 • 355 citations

Multiple integrins mediate cell attachment to cytotactin/tenascin.

1993 • 248 citations

Sequence and tissue distribution of the integrin alpha 9 subunit, a novel partner of beta 1 that is widely distributed in epithelia and muscle [published erratum appears in J Cell Biol 1994 Feb;124(3):395]

1993 • 221 citations

Integrin and Arg-Gly-Asp Dependence of Cell Adhesion to the Native and Unfolded Triple Helix of Collagen Type VI

1993 • 212 citations

Crystal structure of the tenth type III cell adhesion module of human fibronectin

1994 • 207 citations

Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies

1993 • 206 citations

Identification of a novel integrin binding site in fibronectin. Differential utilization by beta 3 integrins.

1994 • 198 citations

A mechanism for divalent cation regulation of beta 3-integrins.

1994 • 196 citations

Integrin alpha IIb beta 3 mediates binding of the Lyme disease agent Borrelia burgdorferi to human platelets.

1993 • 171 citations

Epiligrin, a component of epithelial basement membranes, is an adhesive ligand for alpha 3 beta 1 positive T lymphocytes.

1993 • 165 citations

Binding of recombinant fibrinogen mutants to platelets.

1994 • 154 citations

I domain of beta 2 integrin lymphocyte function-associated antigen-1 contains a binding site for ligand intercellular adhesion molecule-1.

1994 • 151 citations

Structure of the RGD Protein Decorsin: Conserved Motif and Distinct Function in Leech Proteins That Affect Blood Clotting

1994 • 140 citations

Conformational changes in fibrinogen elicited by its interaction with platelet membrane glycoprotein GPIIb-IIIa.

1993 • 130 citations

Plasminogen interacts with human platelets through two distinct mechanisms.

1986 • 129 citations

Site-directed mutagenesis of the arginine-glycine-aspartic acid in vitronectin abolishes cell adhesion

1993 • 125 citations

The leukocyte integrin p150,95 (CD11c/CD18) as a receptor for iC3b. Activation by a heterologous beta subunit and localization of a ligand recognition site to the I domain.

1994 • 118 citations

Mutation of putative divalent cation sites in the alpha 4 subunit of the integrin VLA-4: distinct effects on adhesion to CS1/fibronectin, VCAM-1, and invasin.

1993 • 117 citations

Cell and heparin binding in the distal long arm of laminin: identification of active and cryptic sites with recombinant and hybrid glycoprotein [published erratum appears in J Cell Biol 1993 Dec;123(6 Pt 1):1623]

1993 • 110 citations

Competitive binding of vascular cell adhesion molecule-1 and the HepII/IIICS domain of fibronectin to the integrin alpha 4 beta 1.

1994 • 107 citations

A family of cellular proteins related to snake venom disintegrins.

1994 • 96 citations

Glanzmann thrombasthenia secondary to a Gly273-->Asp mutation adjacent to the first calcium-binding domain of platelet glycoprotein IIb.

1994 • 93 citations

The integrin VLA-2 binds echovirus 1 and extracellular matrix ligands by different mechanisms.

1993 • 65 citations

Neural Crest Cell Interactions with Laminin: Structural Requirements and Localization of the Binding Site for α1β1 Integrin

1994 • 59 citations

Structure/function analysis of the integrin beta 1 subunit by epitope mapping

1993 • 54 citations

Biologically active Arg-Gly-Asp oligopeptides assume a type II .beta.-turn in solution

1993 • 54 citations

The solution structure of echistatin: evidence for disulphide bond rearrangement in homologous snake toxins

1992 • 48 citations

Peptides derived from a sequence within beta 3 integrin bind to platelet alpha IIb beta 3 (GPIIb-IIIa) and inhibit ligand binding.

1993 • 45 citations

An echistatin C-terminal peptide activates GPIIbIIIa binding to fibrinogen, fibronectin, vitronectin and collagen type I and type IV

1993 • 34 citations

Fibronectin inhibits platelet aggregation independently of RGD sequence.

1993 • 22 citations