Role of the ceramide-signaling pathway in cytokine responses to P-fimbriated Escherichia coli.

Programmed Cell Death Induced by Ceramide

1993 • 1,779 citations

TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced “Acidic” sphingomyelin breakdown

1992 • 1,058 citations

Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells.

1986 • 999 citations

Sphingomyelin turnover induced by vitamin D3 in HL-60 cells

1989 • 629 citations

Detection of gangliosides that bind cholera toxin: Direct binding of 125I-labeled toxin to thin-layer chromatograms

1980 • 480 citations

Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation.

1990 • 476 citations

Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase.

1994 • 473 citations

Activation of the Sphingomyelin Signaling Pathway in Intact EL4 Cells and in a Cell-Free System By IL-1β

1993 • 433 citations

Adhesive Properties of Enterobacteriaceae

1980 • 427 citations

Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha.

1991 • 376 citations

Specificity of binding of a strain of uropathogenic Escherichia coli to Gal alpha 1—-4Gal-containing glycosphingolipids.

1985 • 296 citations

Sphingomyelin and derivatives as cellular signals

1991 • 275 citations

Interleukin-1-mediated PGE2 production and sphingomyelin metabolism. Evidence for the regulation of cyclooxygenase gene expression by sphingosine and ceramide.

1992 • 272 citations

Interleukin-6 response of epithelial cell lines to bacterial stimulation in vitro

1992 • 234 citations

Selective cytokine production by epithelial cells following exposure to Escherichia coli

1993 • 225 citations

Characteristics and partial purification of a novel cytosolic, magnesium-independent, neutral sphingomyelinase activated in the early signal transduction of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation.

1994 • 198 citations

[16] Preparation of total nonacid glycolipids for overlay analysis of receptors for bacteria and viruses and for other studies

1987 • 198 citations

Human 55-kDa receptor for tumor necrosis factor coupled to signal transduction cascades.

1992 • 197 citations

The fim genes responsible for synthesis of type 1 fimbriae in Escherichia coli, cloning and genetic organization

1985 • 180 citations

Ceramide 1-phosphate, a novel phospholipid in human leukemia (HL-60) cells. Synthesis via ceramide from sphingomyelin.

1990 • 165 citations

Epithelial cytokine responses and mucosal cytokine networks

1995 • 163 citations

Interleukin-6 induced at mucosal surfaces by gram-negative bacterial infection

1989 • 145 citations

Bacterial lipopolysaccharide has structural similarity to ceramide and stimulates ceramide-activated protein kinase in myeloid cells

1994 • 142 citations

Escherichia coli strains binding neuraminyl α2–3 galactosides

1983 • 140 citations

Sphingomyelinase and cell-permeable ceramide analogs stimulate cellular proliferation in quiescent Swiss 3T3 fibroblasts.

1992 • 128 citations

Ceramide-mediated biology. Determination of structural and stereospecific requirements through the use of N-acyl-phenylaminoalcohol analogs.

1992 • 121 citations

Magnesium-dependent sphingomyelinase

1976 • 110 citations

[50] Chemical synthesis of choline-labeled lecithins and sphingomyelins

1975 • 109 citations

The receptor repertoire defines the host range for attaching Escherichia coli strains that recognize globo-A

1991 • 107 citations

Inhibition of glycoprotein traffic through the secretory pathway by ceramide.

1993 • 94 citations

Ceramide-activated protein phosphatase: partial purification and relationship to protein phosphatase 2A.

1993 • 93 citations

Ceramide induces interleukin 6 gene expression in human fibroblasts.

1995 • 81 citations

Adhesion-dependent activation of mucosal interleukin-6 production

1991 • 68 citations

Studies on the fimbriae of anEscherichia coliO6:K2:H1:F7 strain: Molecular cloning of a DNA fragment encoding a fimbrial antigen responsible for mannose-resistant hemagglutination of human erythrocytes

1983 • 64 citations

Epithelial glucosphingolipid expression as a determinant of bacterial adherence and cytokine production

1994 • 62 citations

Signal transduction by tumor necrosis factor alpha is mediated through a guanine nucleotide-binding protein in osteoblast-like cell line, MC3T3-E1.

1992 • 47 citations

Brefeldin A promotes hydrolysis of sphingomyelin.

1992 • 36 citations

Natural resistance to urinary tract infection determined by endotoxin-induced inflammation

1988 • 22 citations

GalNAcβ1 → 3 terminated glycosphingolipids of human erythrocytes

1986 • 21 citations

Determination of Interleukin 6 in Human Urine and Epithelial Cell Supernatants

1994 • 16 citations