Epithelial cytokine responses and mucosal cytokine networks

A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion.

1995 • 1,205 citations

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome.

1989 • 1,183 citations

Handbook of Mucosal Immunology

1994 • 711 citations

Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung.

1990 • 678 citations

Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry

1993 • 663 citations

Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia.

1989 • 651 citations

Participation of tumor necrosis factor in the mediation of gram negative bacterial lipopolysaccharide-induced injury in rabbits.

1988 • 603 citations

Chemical identification of a glycosphingolipid receptor forEscherichia coliattaching to human urinary tract epithelial cells and agglutinating human erythrocytes

1980 • 528 citations

Salmonella typhimurium attachment to human intestinal epithelial monolayers: transcellular signalling to subepithelial neutrophils.

1993 • 460 citations

The Role of Interleukin-6 in Mucosal IgA Antibody Responses in Vivo

1994 • 460 citations

Expression and generation of interleukin-8, IL-6 and granulocyte-macrophage colony-stimulating factor by bronchial epithelial cells and enhancement by IL-1 beta and tumour necrosis factor-alpha.

1992 • 355 citations

Interleukin-8 expression in Helicobacter pylori infected, normal, and neoplastic gastroduodenal mucosa.

1994 • 349 citations

Interleukin-8 and the neutrophil response to mucosal gram-negative infection.

1993 • 280 citations

Intraepithelial lymphocytes modulate Ia expression by intestinal epithelial cells.

1984 • 272 citations

Gastric Interleukin‐8 and IgA IL‐8 Autoantibodies in Helicobacter pylori Infection

1993 • 262 citations

Difference in susceptibility to gram-negative urinary tract infection between C3H/HeJ and C3H/HeN mice

1984 • 237 citations

Interferon-gamma enhances expression of secretory component, the epithelial receptor for polymeric immunoglobulins.

1987 • 235 citations

Interleukin-6 response of epithelial cell lines to bacterial stimulation in vitro

1992 • 234 citations

Selective cytokine production by epithelial cells following exposure to Escherichia coli

1993 • 225 citations

Neutrophil recruitment and bacterial clearance correlated with LPS responsiveness in local gram-negative infection.

1987 • 203 citations

Elevations of Cytokines Interleukin-1, Interleukin-2 and Tumor Necrosis Factor in the Urine of Patients after Intravesical Bacillus Calmette-Guerin Immunotherapy

1990 • 202 citations

Role of interleukin-8 (IL-8) and an inhibitory effect of erythromycin on IL-8 release in the airways of patients with chronic airway diseases

1994 • 199 citations

Interleukin-8, interleukin-6, and soluble tumour necrosis factor receptor type I release from a human pulmonary epithelial cell line (A549) exposed to respiratory syncytial virus.

1994 • 198 citations

Production and clearance of tumor necrosis factor in rats exposed to endotoxin and dexamethasone

1987 • 196 citations

Interleukin-8 Expression in Normal Nasal Epithelium and Its Modulation by Infection with Respiratory Syncytial Virus and Cytokines Tumor Necrosis Factor, Interleukin-1, and Interleukin-6

1993 • 190 citations

Interleukin-6 response to deliberate colonization of the human urinary tract with gram-negative bacteria

1991 • 184 citations

Persistence of local cytokine production in shigellosis in acute and convalescent stages

1995 • 174 citations

Alveolar type II epithelial cells produce interleukin-6 in vitro and in vivo. Regulation by alveolar macrophage secretory products.

1994 • 173 citations

MCP-1 expression by rat type II alveolar epithelial cells in primary culture.

1993 • 161 citations

Elevated interleukin-8 levels in the urine of patients with urinary tract infections

1993 • 159 citations

Interleukin-6 induced at mucosal surfaces by gram-negative bacterial infection

1989 • 145 citations

Expression and Regulation of Adhesion Molecules ICAM‐1 (CD54) and LFA‐3 (CD58) in Human Intestinal Epithelial Cell Lines

1992 • 127 citations

Microbial lectins and agglutinins : properties and biological activity

1986 • 125 citations

Novel Pseudomonas product stimulates interleukin-8 production in airway epithelial cells in vitro.

1994 • 125 citations

Up‐regulation of the Expression of Secretory Component and HLA Molecules in a Human Colonic Cell Line by Tumour Necrosis Factor‐α and Gamma Interferon

1988 • 120 citations

Enhanced mucosal interleukin-6 and -8 in Helicobacter pylori-positive dyspeptic patients.

1994 • 119 citations

Tumor necrosis factor-independent IL-6 production during murine listeriosis.

1991 • 117 citations

Comparison of Urine and Serum Concentrations of Interleukin-6 in Women with Acute Pyelonephritis or Asymtomatic Bacteriuria

1992 • 114 citations

Transforming growth factor-beta and IL-1 beta act in synergy to enhance IL-6 secretion by the intestinal epithelial cell line, IEC-6.

1993 • 110 citations

Adenovirus-mediated cytokine gene transfer at tissue sites. Overexpression of IL-6 induces lymphocytic hyperplasia in the lung.

1994 • 106 citations

Uroepithelial cells are part of a mucosal cytokine network

1994 • 101 citations

Functional interleukin-2 receptors on intestinal epithelial cells.

1993 • 100 citations

Concentrations of interleukin 6 and tumour necrosis factor in serum and stools of children with Shigella dysenteriae 1 infection.

1993 • 72 citations

Transforming growth factor-beta enhances interleukin-6 secretion by intestinal epithelial cells.

1992 • 70 citations

Genetic factors in host resistance to urinary tract infection

1984 • 69 citations

Adhesion-dependent activation of mucosal interleukin-6 production

1991 • 68 citations

Urinary interleukins in patients receiving intravesical bacillus calmette-guerin therapy for superficial bladder cancer

1989 • 67 citations

Epithelial glucosphingolipid expression as a determinant of bacterial adherence and cytokine production

1994 • 62 citations

CYTOMEGALOVIRUS DIRECTLY ENHANCES MHC CLASS I AND INTERCELLULAR ADHESION MOLECULE-1 EXPRESSION ON CULTURED PROXIMAL TUBULAR EPITHELIAL CELLS

1993 • 61 citations

Cytokine production by the human bladder carcinoma cell line T24 in the presence of bacillus Calmette-Guerin (BCG)

1993 • 58 citations

Regulation of cytokine secretion by cystic fibrosis airway epithelial cells

1993 • 52 citations

Effects of Listeria monocytogenes and Yersinia enterocolitica on cytokine gene expression and release from human polymorphonuclear granulocytes and epithelial (HEp-2) cells

1993 • 46 citations

Neutrophil-Activating Peptide-1/Interleukin-8 Detection in Human Urine during Acute Bladder Inflammation Caused by Transurethral Resection of Superficial Cancer and Bacillus Calmette-Guérin Administration

1991 • 46 citations

Follicle epithelial M cells are a source of interleukin-1 in Peyer's patches.

1993 • 32 citations

Suppressed antibody and interleukin-6 responses to acute pyelonephritis in pregnancy

1994 • 31 citations

Differential expression of interleukin-6, intracellular adhesion molecule 1, and major histocompatibility complex class II molecules in renal carcinoma cells stimulated with S fimbriae of uropathogenic Escherichia coli

1993 • 30 citations

Prostaglandin H Synthase and Lipoxygenase Gene Families in the Epithelial Cell Barrier^a

1994 • 28 citations

Escherichia coli-specific T lymphocytes in experimental pyelonephritis.

1988 • 21 citations

Lps Genotype in the C57 Black Mouse Blackground and its Influence on the Interleukin‐6 Response to E. coli Urinary Tract Infection

1992 • 18 citations

Ciclosporin‐Dependent, nu‐Independent, Mucosal Interleukin 6 Response to Gram‐Negative Bacteria

1990 • 17 citations

Defence of mucous membranes by antibodies, receptor analogues and non-specific host factors

1984 • 12 citations

Cyclosporin A does not Inhibit IL‐lα‐Induced Epithelial Cell IL‐6 Secretion

1993 • 12 citations

Cytokine Regulation of Mast Cell Protease Phenotype and Arachidonic Acid Metabolism

1994 • 6 citations

Leukotrienes Mediate Delayed Airway Effects of 15‐HETE^a

1994 • 3 citations