Inhibition of glycoprotein traffic through the secretory pathway by ceramide.

Functions of Sphingolipids and Sphingolipid Breakdown Products in Cellular Regulation

1989 • 1,251 citations

Molecular dissection of the secretory pathway

1992 • 985 citations

Sphingomyelin turnover induced by vitamin D3 in HL-60 cells

1989 • 629 citations

Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation.

1991 • 621 citations

A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor.

1991 • 478 citations

Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation.

1990 • 476 citations

An update of the enzymology and regulation of sphingomyelin metabolism

1990 • 460 citations

Compartmental organization of the golgi stack

1985 • 442 citations

Tumor Necrosis Factor-α Activates the Sphingomyelin Signal Transduction Pathway in a Cell-Free System

1992 • 428 citations

Ceramide stimulates a cytosolic protein phosphatase.

1992 • 406 citations

Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha.

1991 • 376 citations

Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus.

1990 • 369 citations

A Vital Stain for the Golgi Apparatus

1985 • 344 citations

Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the Golgi apparatus en route to the plasma membrane.

1985 • 297 citations

Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liver

1991 • 282 citations

Sphingomyelin and derivatives as cellular signals

1991 • 275 citations

Molecular trapping of a fluorescent ceramide analogue at the Golgi apparatus of fixed cells: interaction with endogenous lipids provides a trans-Golgi marker for both light and electron microscopy.

1989 • 258 citations

Intracellular transport and metabolism of sphingomyelin

1991 • 236 citations

Lipid recycling between the plasma membrane and intracellular compartments: transport and metabolism of fluorescent sphingomyelin analogues in cultured fibroblasts.

1989 • 221 citations

Sphingolipid metabolism in cultured fibroblasts: microscopic and biochemical studies employing a fluorescent ceramide analogue.

1983 • 194 citations

Sphingomyelin is synthesized in the cis Golgi

1990 • 187 citations

Ceramide: a novel second messenger

1992 • 137 citations

A series of fluorescent N-acylsphingosines: synthesis, physical properties, and studies in cultured cells

1988 • 124 citations

Okadaic acid induces golgi apparatus fragmentation and arrest of intracellular transport

1991 • 113 citations

Effects of a sphingolipid synthesis inhibitor on membrane transport through the secretory pathway

1992 • 103 citations

UDPglucose-ceramide glucosyltransferase from porcine submaxillary glands is associated with the Golgi apparatus

1985 • 58 citations

Elevated ceramide levels in GH4C1 cells treated with retinoic acid

1992 • 57 citations

The Golgi apparatus: insights from lipid biochemistry

1990 • 48 citations