Modulation of Ferritin Η-Chain Expression in Friend Erythroleukemia Cells: Transcriptional and Translational Regulation by Hemin

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

The Metabolic Basis of Inherited Disease.

1983 • 2,885 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

FERRITIN: STRUCTURE, GENE REGULATION, AND CELLULAR FUNCTION IN ANIMALS, PLANTS, AND MICROORGANISMS

1987 • 1,305 citations

Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5' untranslated region of ferritin heavy- and light-subunit mRNAs.

1988 • 684 citations

Identification of the Iron-Responsive Element for the Translational Regulation of Human Ferritin mRNA

1987 • 547 citations

Human erythroid 5-aminolevulinate synthase: promoter analysis and identification of an iron-responsive element in the mRNA.

1991 • 374 citations

Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region.

1987 • 365 citations

Identification of a novel iron-responsive element in murine and human erythroid delta-aminolevulinic acid synthase mRNA.

1991 • 349 citations

Regulation of Synthesis and Turnover of Ferritin in Rat Liver

1966 • 329 citations

Novel mechanism for translational control in regulation of ferritin synthesis by iron.

1976 • 324 citations

Sequential induction of heme pathway enzymes during erythroid differentiation of mouse Friend leukemia virus-infected cells.

1976 • 318 citations

Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron.

1991 • 309 citations

A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron.

1987 • 250 citations

Structural and functional relationships of human ferritin H and L chains deduced from cDNA clones.

1985 • 239 citations

Induction of ferritin subunit synthesis by iron is regulated at both the transcriptional and translational levels.

1988 • 214 citations

Translation of ferritin light and heavy subunit mRNAs is regulated by intracellular chelatable iron levels in rat hepatoma cells.

1987 • 165 citations

Both subunits of rat liver ferritin are regulated at a translational level by iron induction

1986 • 164 citations

Translational repression by a complex between the iron-responsive element of ferritin mRNA and its specific cytoplasmic binding protein is position-dependent in vivo.

1990 • 147 citations

Properties of human tissue isoferritins

1978 • 135 citations

Modulation of the RNA-binding activity of a regulatory protein by iron in vitro: switching between enzymatic and genetic function?

1992 • 133 citations

Chemically induced murine erythroleukemic differentiation

1980 • 128 citations

A model for the structure and functions of iron-responsive elements

1988 • 119 citations

Multiple mechanisms of iron-induced ferritin synthesis in HeLa cells

1985 • 119 citations

Derepression of Ferritin Mmessenger RNA Translation by Hemin in Vitro

1990 • 118 citations

Hemin enhances the differentiation of mouse 3T3 cells to adipocytes

1981 • 115 citations

Translational repression in eukaryotes: partial purification and characterization of a repressor of ferritin mRNA translation.

1988 • 109 citations

Regulation of transferrin receptors in human hematopoietic cell lines.

1984 • 100 citations

Transcriptional regulation of ferritin H and L subunits in adult erythroid and liver cells from the mouse

1989 • 99 citations

Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene.

1986 • 83 citations

The Effect of Chelating Agents on Cellular Iron Metabolism

1976 • 75 citations

Transferrin receptors of human fibroblasts. Analysis of receptor properties and regulation

1982 • 75 citations

Expression of transferrin receptors in phytohemagglutinin-stimulated human T-lymphocytes. Evidence for a three-step model.

1986 • 70 citations

Influence of altered transcription on the translational control of human ferritin expression.

1987 • 64 citations

Ferritin as an iron-storage protein: mechanisms of iron uptake

1986 • 58 citations

Human Ferritin Gene Expression

1988 • 56 citations

Ferritin synthesis in differentiating Friend erythroleukemic cells.

1987 • 53 citations

Regulation of intracellular iron distribution in K562 human erythroleukemia cells.

1986 • 49 citations

Multiple post-transcriptional regulatory mechanisms in ferritin gene expression.

1989 • 42 citations

Positive modulation of hemoglobin, heme, and transferrin receptor synthesis by murine interferon-alpha and -beta in differentiating Friend cells. Pivotal role of heme synthesis.

1991 • 32 citations

The synthesis and turnover of ferritin in rat L-6 cells. Rates and response to iron, actinomycin D, and desferrioxamine.

1984 • 27 citations

Intracellular heme coordinately modulates globin chain synthesis, transferrin receptor number, and ferritin content in differentiating Friend erythroleukemia cells

1991 • 27 citations

[31] Characterization of in vitro translation products

1987 • 24 citations

Transferrin receptor regulation is coupled to intracellular ferritin in proliferating and differentiating HL60 leukemia cells

1985 • 23 citations

Isoferritins in rat Kupffer cells, hepatocytes, and extrahepatic macrophages. Biosynthesis in cell suspensions and cultures in response to iron.

1981 • 19 citations

Inducibility of spleen focus-forming virus by BrdUrd is controlled by the differentiated state of the cell.

1981 • 18 citations

Role of protein synthesis in the accumulation of ferritin mRNA during exposure of cells to iron

1990 • 18 citations

Ferritin is not a required intermediate for iron utilization in heme synthesis

1984 • 12 citations