Human Ferritin Gene Expression

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

A Clinical Evaluation of Serum Ferritin as an Index of Iron Stores

1974 • 961 citations

Ferritin: design and formation of an iron-storage molecule

1984 • 559 citations

Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene

1987 • 489 citations

On ferritin heterogeneity. Further evidence for heteropolymers.

1978 • 464 citations

Bidirectional SV40 Transcription Mediated by Tandem Sp1 Binding Interactions

1985 • 413 citations

Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene.

1985 • 391 citations

Ferritin: structure, biosynthesis, and role in iron metabolism.

1978 • 390 citations

Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region.

1987 • 365 citations

Ferritin in Serum

1975 • 352 citations

Regulation of Synthesis and Turnover of Ferritin in Rat Liver

1966 • 329 citations

Novel mechanism for translational control in regulation of ferritin synthesis by iron.

1976 • 324 citations

Iodine 131 antiferritin, a new treatment modality in hepatoma: a Radiation Therapy Oncology Group study.

1985 • 259 citations

A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron.

1987 • 250 citations

Structural and functional relationships of human ferritin H and L chains deduced from cDNA clones.

1985 • 239 citations

Identification of leukemia-associated inhibitory activity as acidic isoferritins. A regulatory role for acidic isoferritins in the production of granulocytes and macrophages.

1981 • 194 citations

A study of 609 HLA haplotypes marking for the hemochromatosis gene: (1) mapping of the gene near the HLA-A locus and characters required to define a heterozygous population and (2) hypothesis concerning the underlying cause of hemochromatosis-HLA association.

1987 • 178 citations

Translation of ferritin light and heavy subunit mRNAs is regulated by intracellular chelatable iron levels in rat hepatoma cells.

1987 • 165 citations

Both subunits of rat liver ferritin are regulated at a translational level by iron induction

1986 • 164 citations

Suppressive Effect of Ferritin on in Vitro Lymphocyte Function

1979 • 162 citations

Prognostic importance of serum ferritin in patients with Stages III and IV neuroblastoma: the Childrens Cancer Study Group experience.

1985 • 161 citations

Differences in the regulation of messenger RNA for housekeeping and specialized-cell ferritin. A comparison of three distinct ferritin complementary DNAs, the corresponding subunits, and identification of the first processed in amphibia.

1987 • 156 citations

Structure and Physiological Functions of Ferritin

1951 • 135 citations

Structure of gene and pseudogenes of human apoferritin H

1986 • 132 citations

Adaptive responses of rat tissue isoferritins to iron administration. Changes in subunit synthesis, isoferritin abundance, and capacity for iron storage.

1981 • 131 citations

Human isoferritins in normal and disease states.

1977 • 128 citations

Detection and isolation of a hepatic membrane receptor for ferritin.

1983 • 109 citations

Iron incorporation into apoferritin. The role of apoferritin as a ferroxidase.

1986 • 107 citations

Characterization of Serum Ferritin in Iron Overload: Possible Identity to Natural Apoferritin

1977 • 106 citations

Structure and expression of ferritin genes in a human promyelocytic cell line that differentiates in vitro.

1986 • 104 citations

Cloning of the gene coding for human L apoferritin

1986 • 104 citations

Carcino-Foetal Human Liver Ferritins

1973 • 103 citations

Detection of three protein binding sites in the serum-regulated promoter of the human gene encoding the 70-kDa heat shock protein.

1987 • 102 citations

Regulation in Vitro of Metallothionein Gene Binding Factors

1987 • 101 citations

Assignment of human ferritin genes to chromosomes 11 and 19q13.3→19qter

1985 • 100 citations

Cloning and sequencing of a full length cDNA coding for a human apoferritin H chain: evidence for a multigene family.

1984 • 93 citations

Hemin, chelatable iron, and the regulation of transferrin receptor biosynthesis.

1985 • 91 citations

Processed pseudogenes

1984 • 91 citations

Conservation in rat liver of light and heavy subunit sequences of mammalian ferritin. Presence of unique octopeptide in the light subunit.

1984 • 89 citations

Ferritin Synthesis by Human T Lymphocytes

1980 • 85 citations

Structure and expression of the chicken ferritin H-subunit gene.

1987 • 85 citations

Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene.

1986 • 83 citations

Subunit dimers in sheep spleen apoferritin. The effect on iron storage.

1983 • 78 citations

Cell proliferation and expression of the transferrin receptor gene: promoter sequence homologies and protein interactions.

1986 • 76 citations

Structure, organization, and regulation of human metallothionein IF gene: differential and cell-type-specific expression in response to heavy metals and glucocorticoids.

1986 • 76 citations

Differential turnover of rat liver isoferritins.

1980 • 76 citations

Chromosomal assignments of the genes coding for human types II, III, and IV collagen: a dispersed gene family.

1985 • 72 citations

Human serum ferritin G-peptide is recognized by anti-L ferritin subunit antibodies and concanavalin-A

1987 • 68 citations

Molecular structure of the human argininosuccinate synthetase gene: occurrence of alternative mRNA splicing.

1984 • 68 citations

Heterozygosity for HLA-Linked Hemochromatosis as a Likely Cause of the Hepatic Siderosis Associated With Sporadic Porphyria Cutanea Tarda

1985 • 67 citations

Abnormality in tissue isoferritin distribution in idiopathic haemochromatosis

1974 • 66 citations

Human ferritin gene is assigned to chromosome 19.

1983 • 63 citations

Sialic Acid and the Microheterogeneity of Human Serum Ferritin

1980 • 62 citations

The Iron Content of Jejunal Mucosa Obtained by Crosby’s Biopsy in Hemochromatosis and Hemosiderosis

1966 • 60 citations

Characterization of human ferritin H chain synthetized in Escherichia coli

1987 • 59 citations

The human transferrin gene: 5′ region contains conserved sequences which match the control elements regulated by heavy metals, glucocorticoids and acute phase reaction

1986 • 54 citations

Ferritin synthesis in differentiating Friend erythroleukemic cells.

1987 • 53 citations

Ferritin H and L chains are derived from different multigene families.

1985 • 53 citations

Isolation and characterization of a cDNA clone for human ferritin heavy chain.

1984 • 51 citations

Microheterogeneity of horse spleen ferritin and apoferritin

1971 • 51 citations

Structure of human ferritin light subunit messenger RNA: comparison with heavy subunit message and functional implications.

1985 • 50 citations

Regulation of intracellular iron distribution in K562 human erythroleukemia cells.

1986 • 49 citations

Human ferritin H and L sequences lie on ten different chromosomes

1987 • 49 citations

Genes for the ?H? subunit of human ferritin are present on a number of human chromosomes

1985 • 41 citations

The ultrastructure of ferritin macromolecules

1978 • 37 citations

The Human Gene Map 15 April 1986: The Morbid Anatomy of the Human Genome

1986 • 35 citations

Effect of acidic and basic isoferritins on in vitro growth of human granulocyte-monocyte progenitors

1986 • 32 citations

Human ferritins present in the sera of nude mice transplanted with human neuroblastoma or hepatocellular carcinoma.

1984 • 28 citations

Human ferritin light chain gene sequences mapped to several sorted chromosomes

1985 • 24 citations

Assembly of intra- and interspecies hybrid apoferritins.

1980 • 24 citations

The effect of isoferritins on granulopoiesis

1986 • 23 citations

Ferritins in malignant and non‐malignant lymphoid cells

1986 • 23 citations

Characteristics of ferritins in human milk secretions: Similarities to serum and tissue isoferritins

1986 • 21 citations

The effect of isoferritins on granulopoiesis

1986 • 20 citations

Cell-specific properties of red cell and liver ferritin from bullfrog tadpoles probed by phosphorylation in vitro.

1984 • 20 citations

Changes in the amount of nonhaem iron in the plasma, whole body, and selected organs during the postlarval life of the lamprey Geotria australis

1986 • 19 citations

Two Molecular Forms of Ferritin in Rabbit Marrow

1968 • 17 citations

Biochemical and immunological characteristics of ferritin from HL-60, U-937 and K-562 cell lines: Implications for haemopoietic regulation

1984 • 9 citations

Neptune's rings

1986 • 5 citations