Derepression of Ferritin Mmessenger RNA Translation by Hemin in Vitro

FERRITIN: STRUCTURE, GENE REGULATION, AND CELLULAR FUNCTION IN ANIMALS, PLANTS, AND MICROORGANISMS

1987 • 1,305 citations

Iron Transport and Storage Proteins

1980 • 1,183 citations

Iron-Responsive Elements: Regulatory RNA Sequences That Control mRNA Levels and Translation

1988 • 707 citations

Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5' untranslated region of ferritin heavy- and light-subunit mRNAs.

1988 • 684 citations

Identification of the Iron-Responsive Element for the Translational Regulation of Human Ferritin mRNA

1987 • 547 citations

A specific mRNA binding factor regulates the iron-dependent stability of cytoplasmic transferrin receptor mRNA

1989 • 511 citations

Ferritin: structure, biosynthesis, and role in iron metabolism.

1978 • 390 citations

Oxidation-Reduction and the Molecular Mechanism of a Regulatory RNA-Protein Interaction

1989 • 387 citations

Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region.

1987 • 365 citations

Binding of a Cytosolic Protein to the Iron-Responsive Element of Human Ferritin Messenger RNA

1988 • 363 citations

Regulation of Synthesis and Turnover of Ferritin in Rat Liver

1966 • 329 citations

Novel mechanism for translational control in regulation of ferritin synthesis by iron.

1976 • 324 citations

Nonenzymatic cleavage of proteins by reactive oxygen species generated by dithiothreitol and iron.

1985 • 268 citations

A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron.

1987 • 250 citations

Transcriptional Activation of the Heme Oxygenase Gene by Heme and Cadmium in Mouse Hepatoma Cells

1989 • 230 citations

HEMOGLOBIN SYNTHESIS IN RABBIT RETICULOCYTES IN VITRO

1956 • 202 citations

Control of Protein Synthesis in Reticulocyte Lysates by Haemin

1973 • 201 citations

Hemin-mediated oxidative degradation of proteins.

1984 • 173 citations

Translation of ferritin light and heavy subunit mRNAs is regulated by intracellular chelatable iron levels in rat hepatoma cells.

1987 • 165 citations

Both subunits of rat liver ferritin are regulated at a translational level by iron induction

1986 • 164 citations

Hydroxyl free radical mediated formation of 8-hydroxyguanine in isolated DNA

1988 • 161 citations

The influence of heme-binding proteins in heme-catalyzed oxidations

1988 • 141 citations

Purification of a Specific Repressor of Ferritin mRNA Translation from Rabbit Liver

1989 • 138 citations

Regulation of Protein Synthesis

1967 • 133 citations

Conservation of ferritin heavy subunit gene structure: implications for the regulation of ferritin gene expression.

1987 • 109 citations

Translational repression in eukaryotes: partial purification and characterization of a repressor of ferritin mRNA translation.

1988 • 109 citations

Translational control of gene expression in a normal fibroblast. Characterization of a subclass of mRNAs with unusual kinetic properties

1986 • 98 citations

Hemin, chelatable iron, and the regulation of transferrin receptor biosynthesis.

1985 • 91 citations

Requirements for the Translational Repression of Ferritin Transcripts in Wheat Germ Extracts by a 90-kDa Protein from Rabbit Liver

1989 • 80 citations

Studies of the ATP-dependent proteolytic enzyme, protease La, from Escherichia coli.

1982 • 77 citations

Disulfide Bond Formation in the Regulation of eIF-2 α Kinase by Heme

1989 • 66 citations

On the Mechanism of Iron-induced Synthesis of Apoferritin in HeLa Cells

1969 • 65 citations

Mechanism of increase of heme oxygenase activity induced by hemin in cultured pig alveolar macrophages

1979 • 61 citations

12 Regulation of Protein Synthesis

1987 • 60 citations

The effects of inhibition of heme synthesis on the intracellular localization of iron in rat reticulocytes

1989 • 56 citations

Regulation of heme synthesis in erythroid cells: hemin inhibits transferrin iron utilization but not protoporphyrin synthesis

1985 • 51 citations

Multiple post-transcriptional regulatory mechanisms in ferritin gene expression.

1989 • 42 citations

Increase in surface expression of transferrin receptors on cultured hepatocytes of adult rats in response to iron deficiency.

1988 • 34 citations

Hormonal regulation of heme oxygenase induction in avian hepatocyte culture

1985 • 30 citations

Effects of porphyrins on proteins of cytosol and plasma. In vitro photo-oxidation and cross-linking of proteins by naturally occurring and synthetic porphyrins.

1987 • 15 citations

Decreased heme content and cessation of cell growth in cultured chick embryo fibroblasts in the presence of horse serum: Stimulation of heme synthesis and cell growth by iron

1982 • 6 citations