Drug Resistance in Human Helminths: Current Situation and Lessons from Livestock
Data up to Jan 2025
Total Citations Per Year
Abstract
References (148)
Infectious Diseases of Humans: Dynamics and Control
1992 • 7,897 citations
A simple device for quantitative stool thick-smear technique in Schistosomiasis mansoni.
1972 • 2,386 citations
World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) methods for the detection of anthelmintic resistance in nematodes of veterinary importance
1992 • 1,621 citations
Feline Clinical Parasitology
2002 • 617 citations
Evaluating treatment protocols to prevent antibiotic resistance
1997 • 495 citations
Resistance to praziquantel: direct evidence from Schistosoma mansoni isolated from Egyptian villagers.
1999 • 483 citations
Drug-Resistant Schistosomiasis: Resistance to Praziquantel and Oxamniquine Induced in Schistosoma Mansoni in Mice is Drug Specific
1994 • 470 citations
Benzimidazole resistance in Haemonchus contortus is correlated with a conserved mutation at amino acid 200 in β-tubulin isotype 1
1994 • 412 citations
Worm control and anthelmintic resistance: adventures with a model
1995 • 369 citations
CONTROL OF SCHISTOSOMIASIS
1973 • 338 citations
Characterization of Isolates of Schistosoma mansoni from Egyptian Villagers that Tolerate High Doses of Praziquantel
1996 • 316 citations
Efficacy and Side Effects of Praziquantel in an Epidemic Focus of Schistosoma mansoni
1995 • 305 citations
Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog1Note: Nucleotide sequence data reported in this paper have been submitted to the GenBank data base with the accession number AF 003908.1
1998 • 290 citations
Molecular mechanisms of drug resistance
1990 • 279 citations
Evaluation of Kato Thick-Smear Technique for Quantitative Diagnosis of Helminth Infections
1968 • 272 citations
Underestimation of Schistosoma mansoni prevalences
1992 • 271 citations
β-Tubulin Genes from the Parasitic NematodeHaemonchus contortusModulate Drug Resistance inCaenorhabditis elegans
1995 • 265 citations
Characterization of Mutations in the Beta-Tubulin Gene of Benomyl-Resistant Field Strains ofVenturia inaequalisand Other Plant Pathogenic Fungi
1992 • 264 citations
Anthelmintic resistance: past, present and future
1999 • 251 citations
Antischistosomal drugs: Past, present … and future?
1995 • 250 citations
The control of schistosomiasis. Second report of the WHO expert committee
1993 • 240 citations
Assessment of the incidence of substandard drugs in developing countries
1997 • 228 citations
The prevalence of anthelmintic resistance in nematode parasites of sheep in Southern Latin America: Brazil
1996 • 227 citations
Failure of Mebendazole in Treatment of Human Hookworm Infections in the Southern Region of Mali
1997 • 218 citations
Population Biology of Parasitic Nematodes: Applications of Genetic Markers
1998 • 217 citations
Detecting benzimidazole resistance with faecal egg count reduction tests and in vitro assays
1989 • 217 citations
Control Strategies for Human Intestinal Nematode Infections
1999 • 216 citations
Day-to-Day Egg Count Fluctuation in Schistosoma mansoni Infection and its Operational Implications
1996 • 202 citations
Egg hatch as an in vitro assay of thiabendazole resistance in nematodes
1976 • 182 citations
Pharmacology of Anthelmintic Resistance
1999 • 182 citations
How long before resistance makes it impossible to control some field strains of Haemonchus contortus in South Africa with any of the modern anthelmintics?
1997 • 179 citations
Onchocerciasis and its ControlOnchocerciasis and its Control, WHO Technical Report Series No. 852, Report of WHO Expert Committee on Onchocerciasis Control, Office of Publications, WHO, Geneva, Switzerland, ISBN 0512-3054
1996 • 176 citations
Short report: diminished susceptibility to praziquantel in a Senegal isolate of Schistosoma mansoni.
1995 • 175 citations
Clinical Parasitology: 9th edn.
1984 • 168 citations
Haemonchus contortus: Selection at a Glutamate-Gated Chloride Channel Gene in Ivermectin- and Moxidectin-Selected Strains
1998 • 166 citations
The prevalence of anthelmintic resistance in nematode parasites of sheep in Southern Latin America: General overview
1996 • 161 citations
Failure of pyrantel in treatment of human hookworm infections (Ancylostoma duodenale) in the Kimberley region of North West Australia
1997 • 157 citations
Amino acid alterations in the benA (β‐tubulin) gene of Aspergillus nidulans that confer benomyl resistance
1992 • 156 citations
Chemotherapy of Nematode Infections of Veterinary Importance, with Special Reference to Drug Resistance
1995 • 152 citations
Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus
1998 • 149 citations
Resistance of parasites to antiparasitic drugs
1992 • 149 citations
Genetic variability of the beta-tubulin genes in benzimidazole-susceptible and -resistant strains of Haemonchus contortus.
1994 • 148 citations
Avermectin inhibition of larval development in Haemonchus contortus — Effects of ivermectin resistance
1995 • 147 citations
Modelling and forecasting
1999 • 142 citations
Quick Kato Smear for Field Quantification of Schistosoma Mansoni Eggs *
1980 • 140 citations
Epidemiology, immunology and chemotherapy of Schistosoma mansoni infections in a recently exposed community in Senegal.
1994 • 132 citations
Anthelmintics
1997 • 130 citations
Management of anthelmintic resistance: Inheritance of resistance and selection with persistent drugs
1996 • 129 citations
Praziquantel: An urgent and exciting challenge
1996 • 127 citations
Evaluating measures to control intestinal parasitic infections.
1992 • 126 citations
Quantitative variability of nematode egg counts in faeces: a study among rural Kenyans
1981 • 123 citations
Chemotherapy of Schistosomiasis: An Update
1998 • 121 citations
Anthelmintic resistance revisited: under-dosing, chemoprophylactic strategies, and mating probabilities
1999 • 121 citations
The African programme for onchocerciasis control: Preparing to launch
1995 • 114 citations
Hookworm disease : current status and new directions
1990 • 111 citations
New genetic and practical implications of selection for anthelmintic resistance in parasitic nematodes
1995 • 109 citations
Epidemiology of Schistosoma mansoni Infection in a Recently Exposed Community in Northern Senegal
1993 • 109 citations
Avermectin\milbemycin resistance in trichostrongyloid nematodes
1998 • 107 citations
Sequences of β-tubulin cDNA from benzimidazole-susceptible and -resistant strains of Teladorsagia circumcincta, a nematode parasite of small ruminants
1996 • 103 citations
Haemonchus contortus: Sequence Heterogeneity of Internucleotide Binding Domains from P-Glycoproteinsand an Association with Avermectin/Milbemycin Resistance
1999 • 102 citations
Drug resistance in schistosomes
1993 • 101 citations
Quantitative diagnosis of Schistosoma infections by measurement of circulating antigens in serum and urine.
1994 • 100 citations
Efficacy of praziquantel against Schistosoma mansoni in northern Senegal
1998 • 99 citations
Anthelmintic resistance in nematode parasites of sheep: learning from the Australian experience
1995 • 97 citations
PCR diagnosis of benzimidazole-susceptibity or -resistance in natural populations of the small ruminant parasite, Teladorsagia circumcincta
1999 • 96 citations
Intensity of reinfection with Ascaris lumbricoides and its implications for parasite control
1992 • 94 citations
Worm burdens in schistosome infections
1996 • 91 citations
Therapeutic Evaluation of Two Different Dose Regimens of Praziquantel in a Recent Schistosoma mansoni Focus in Northern Senegal
1997 • 90 citations
A model for variations in single and repeated egg counts in schistosoma mansoni infections
1992 • 89 citations
Oxamniquine CuresSchistosoma mansoniInfection in a Focus in Which Cure Rates with Praziquantel Are Unusually Low
1997 • 87 citations
Schistosome resistance to praziquantel: Fact or artifact?
1996 • 85 citations
Can we deworm this wormy world?
1998 • 85 citations
Intraspecimen Fecal Egg Count Variation in Schistosoma mansoni Infection
1997 • 83 citations
Larval development test for detection of anthelmintic resistant nematodes
1988 • 83 citations
Schistosoma mansoni:Maturation Rate and Drug Susceptibility of Different Geographic Isolates
1997 • 80 citations
Trichostrongylus colubrifortnis and Ostertagia circumcincta resistant to levamisole, morantel tartrate and thiabendazole:occurrence of field strains
1979 • 78 citations
The disposition of antiparasitic drugs in relation to the development of resistance by parasites of livestock
1994 • 78 citations
A larval development assay for the simultaneous detection of broad spectrum anthelmintic resistance
1990 • 77 citations
Anthelmintic resistance in human helminths: Learning from the problems with worm control in livestock
1997 • 77 citations
Use of the egg hatch assay on sheep faecal samples for the detection of benzimidazole resistant nematodes
1989 • 77 citations
An International Initiative on Praziquantel Use
1998 • 75 citations
Anthelmintic resistance in goats in peninsular Malaysia
1994 • 71 citations
Comparison of the efficacy of mebendazole, albendazole and pyrantel in treatment of human hookworm infections in the Southern Region of Mali, West Africa
1999 • 70 citations
The role of drugs in the control of parasitic nematode infections: must we do without?
1997 • 68 citations
Micromotility meter: an instrument designed to evaluate the action of drugs on motility of larval and adult nematodes
1986 • 67 citations
Development of anthelmintic resistance in nematodes from sheep in Australia subjected to different treatment frequencies
1983 • 67 citations
The USAID/Government of Egypt's Schistosomiasis Research Project (SRP)
1998 • 66 citations
Use of praziquantel against schistosomiasis: a review of current status
1994 • 65 citations
Anthelmintic drug resistance in the UK
1989 • 64 citations
WHO model prescribing information: Drugs used in parasitic diseases
1991 • 64 citations
Schistosoma mansoni: Hycanthone/oxamniquine resistance is controlled by a single autosomal recessive gene
1992 • 63 citations
EFFECTS OF A PREVENTIVE AND SUPPRESSIVE CONTROL SCHEME ON THE DEVELOPMENT OF THIABENDAZOLE‐RESISTANCE IN OSTERTAGIA SPP
1982 • 62 citations
Laboratory Selection of Haemonchus contortus for Resistance to Ivermectin
1988 • 61 citations
Schistosomiasis control in the People's Republic of China
1997 • 60 citations
The problem of escalating resistance of Haemonchus contortus to the modern anthelmintics in South Africa.
1989 • 60 citations
Comparison of six in vitro tests in determining benzimidazole and levamisole resistance in Haemonchus contortus and Ostertagia circumcincta of sheep
1999 • 59 citations
Pharmacology of anthelmintic resistance
1996 • 58 citations
Is Schistosomicidal Chemotherapy Sub-curative? Implications for Drug Resistance
1998 • 58 citations
Genetic variation in parasitic nematodes and its implications
1994 • 57 citations
Pharmaceutical quality of anthelmintics sold in Kenya
1998 • 57 citations
The Development of Resistance to Anthelmintics: A Perspective with an Emphasis on the Antischistosomal Drug Praziquantel
1997 • 56 citations
Evidence of multiple mechanisms of avermectin resistance in Haemonchus contortus—comparison of selection protocols
1998 • 56 citations
Ivermectin Binding Sites in Sensitive and Resistant Haemonchus contortus
1994 • 55 citations
Characterization of an acetylcholine receptor gene of haemonchus contortus in relation to levamisole resistance1Note: Nucleotide sequence data reported in this paper are available in the GenBank™ database under accession No. U72490.1
1997 • 54 citations
Methodology and interpretation of parasitological surveillance of intestinal schistosomiasis in Maniema, Kivu Province, Zaire.
1985 • 54 citations
Schistosoma mansoni: Genetic Complementation Analysis Shows That Two Independent Hycanthone/Oxamniquine-Resistant Strains Are Mutated in the Same Gene
1993 • 53 citations
The association between frequency of thiabendazole treatment and the development of resistance in field isolates of Ostertagia spp. of sheep
1984 • 51 citations
Beta-tubulin gene polymorphism and benzimidazole resistance in Trichostrongylus colubriformis
1996 • 50 citations
Alterations in cytochrome-c oxidase expression between praziquantel-resistant and susceptible strains of Schistosoma mansoni
1998 • 45 citations
Evolution of operational research studies and development of a national control strategy against intestinal helminths in Pemba Island, 1988-92.
1995 • 44 citations
Field trials of praziquantel and oxamniquine for the treatment of schistosomiasis mansoni in Burundi
1987 • 43 citations
Research note Use of P-glycoprotein gene probes to investigate anthelmintic resistance in Haemonchus contortus and comparison with Onchocerca volvulusfn1fn1Note: Sequence data reported in this paper are available in the GenBankTM database under the accession numbers U94401 (Haemonchus contortus) and U94399 and U94400 (Onchocerca volvulus).
1998 • 43 citations
The contribution of host-related factors to low cure rates of praziquantel for the treatment of Schistosoma mansoni in Senegal.
1999 • 41 citations
Suspected resistance of Ostertagia ostertagi in cattle to levamisole
1987 • 39 citations
Antischistosomal drugs and clinical practice.
1993 • 37 citations
Anthelmintic resistance in nematodes of farm animals
1995 • 37 citations
Uncertainties in the epidemiology and control of schistosomiasis
1996 • 34 citations
Flow cytometry analysis of drug transport mechanisms in Haemonchus contortus susceptible or resistant to anthelmintics
1999 • 33 citations
Schistosomiasis mansoni in Burundi: progress in its control since 1985.
1993 • 31 citations
Selection for high levamisole resistance in Haemonchus contortus monitored with an egg-hatch assay
1997 • 31 citations
Fluctuation of Schistosome Circulating antigen Levels in Urine of Individuals with Schistosoma mansoni Infection in Burundi
1996 • 31 citations
Drug resistance to schistosomicides and other anthelmintics of medical significance
1994 • 31 citations
Quality control in generic anthelmintics: Is it adequate?
1997 • 30 citations
Comparison of the sensitivity of different geographical races of Onchocerca volvulus microfilariae to ivermectin: studies in vitro
1994 • 30 citations
Anthelmintics: a review of their comparative clinical pharmacology
1997 • 30 citations
Impact of drug dosage and brand on bioavailability and efficacy of praziquantel
1995 • 28 citations
Resistance to anthelmintics and the implications for animal production.
1985 • 25 citations
Treatment of mixed Oesophagostomum and hookworm infection: effect of albendazole, pyrantel pamoate, levamisole and thiabendazole
1993 • 24 citations
Control of Schistosoma mansoni and intestinal helminths: 8-year follow-up of an urban school programme in Bujumbura, Burundi
1994 • 24 citations
Chemotherapy of Human Nematodes: Learning from the Problems in Sheep
1995 • 24 citations
Cost and effectiveness of different approaches to schistosomiasis control in Africa.
1986 • 23 citations
Prevalence of benzimidazole resistance of nematodes in sheep in The Netherlands
1987 • 22 citations
Development and validation of an in vitro Trichostrongylus colubriformis motility assay
1987 • 22 citations
Occurrence and dissemination of anthelmintic resistance in South Africa, and management of resistant worm strains.
1990 • 21 citations
Reliability and reproducibility of the larval paralysis test as an in vitro method for the detection of anthelmintic resistance of nematodes against levamisole and morantel tartrate
1989 • 21 citations
Tubulin, resistance and worms
1995 • 20 citations
Use of arithmetic and geometric means in the calculation of anthelmintic efficacy
1997 • 19 citations
A survey of ovine parasite control practices in Tennessee
1992 • 18 citations
An integrated system for the control of the major human helminth parasites.
1990 • 15 citations
The nicotinic acetylcholine α-subunit gene tar-1 is located on the X chromosome but its coding sequence is not involved in levamisole resistance in an isolate of Trichostrongylus colubriformis
1997 • 14 citations
Chemotherapy: future problems.
1990 • 11 citations
For the new millennium: control of helminth diseases throughout the world
1993 • 9 citations
Benzimidazole resistance in nematodes on a dairy goat farm in Belgium.
1990 • 8 citations
Resistance of Onchocerca volvulus microfilariae to diethylcarbamazine.
1957 • 7 citations
Computer models applied to drug resistance in parasites.
1990 • 6 citations
Anthelmintic resistance in nematodes of cattle
1994 • 3 citations
[Use of anthelmintics for nematode control in sheep in West Germany: results of a survey].
1992 • 3 citations
Call for renewed drive against schistosomiasis
1998 • 2 citations