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Haemonchus contortus: Selection at a Glutamate-Gated Chloride Channel Gene in Ivermectin- and Moxidectin-Selected Strains

Data up to Jan 2025

Published1998
Citations166
References39

Total Citations Per Year

Abstract

References (39)

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans

1994 • 716 citations

A point mutation in a Drosophila GABA receptor confers insecticide resistance

1993 • 552 citations

The GABAergic nervous system of Caenorhabditis elegans

1993 • 491 citations

avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans

1997 • 350 citations

Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog1Note: Nucleotide sequence data reported in this paper have been submitted to the GenBank data base with the accession number AF 003908.1

1998 • 290 citations

Haemonchus contortus: Ivermectin-Induced Paralysis of the Pharynx

1993 • 226 citations

The Mechanism of Action of Avermectins in Caenorhabditis Elegans: Correlation between Activation of Glutamate-Sensitive Chloride Current, Membrane Binding, and Biological Activity

1995 • 223 citations

Resistance of field strains of Haemonchus contortus to ivermectin, closantel, rafoxanide and the benzimidazoles in South Africa

1988 • 216 citations

The inhibitory glycine receptor: architecture, synaptic localization and molecular pathology of a postsynaptic ion-channel complex

1995 • 205 citations

Anthelmintic resistance in nematodes: Extent, recent understanding and future directions for control and research

1990 • 178 citations

Reversal of P-glycoprotein-associated multidrug resistance by ivermectin

1997 • 174 citations

Avermectin B1a, a paralyzing anthelmintic that affects interneurons and inhibitory motoneurons in Ascaris.

1980 • 164 citations

Genetic variability of the beta-tubulin genes in benzimidazole-susceptible and -resistant strains of Haemonchus contortus.

1994 • 148 citations

The abamectin derivative ivermectin is a potent P-glycoprotein inhibitor

1996 • 124 citations

Two Populations of L-Glutamate Receptors on Locust Muscle Fibres

1973 • 119 citations

Tight genetic linkage between the kdr insecticide resistance trait and a voltage-sensitive sodium channel gene in the house fly.

1994 • 118 citations

Multiple resistance to ivermectin and oxfendazole in Cooperia species of cattle in New Zealand

1995 • 116 citations

UNUSUAL POPULATION GENETICS OF A PARASITIC NEMATODE: mtDNA VARIATION WITHIN AND AMONG POPULATIONS

1992 • 107 citations

Anthelmintic resistance by Haemonchus contortus to ivermectin in Brazil: a preliminary report

1989 • 96 citations

Molecular biology and electrophysiology of glutamategated chloride channels of invertebrates

1996 • 95 citations

Cholinergic receptor mutants of the nematode Caenorhabditis elegans

1987 • 92 citations

An electrophysiological preparation ofAscaris suumpharyngeal muscle reveals a glutamate-gated chloride channel sensitive to the avermectin analogue, milbemycin D

1996 • 91 citations

The multidrug resistance P-glycoprotein modulates cell regulatory volume decrease.

1996 • 89 citations

Mutual resistance to avermectins and milbemycins: oral activity of ivermectin and moxidectin against ivermectin-resistant and susceptible nematodes

1993 • 87 citations

Demonstration of co-resistance of Haemonchus contortus to ivermectin and moxidectin

1993 • 83 citations

Avermectin-sensitive chloride currents induced by Caenorhabditis elegans RNA in Xenopus oocytes.

1991 • 83 citations

An Amino Acid Substitution in the Pore Region of a Glutamate-gated Chloride Channel Enables the Coupling of Ligand Binding to Channel Gating

1996 • 76 citations

A survey of anthelmintic resistance in nematode parasites of goats in Denmark

1996 • 70 citations

Reporter Gene Constructs Suggest That the Caenorhabditis Elegans Avermectin Receptor β-Subunit is Expressed Solely in the Pharynx

1997 • 61 citations

Ivermectin Binding Sites in Sensitive and Resistant Haemonchus contortus

1994 • 55 citations

Ivermectin‐resistant Haemonchus contortus in Australia

1993 • 53 citations

Resistance by Haemonchus contortus to ivermectin in angora goats.

1990 • 52 citations

Unusual Population Genetics of a Parasitic Nematode: mtDNA Variation Within and among Populations

1992 • 50 citations

Glutamate-gated inhibitory currents of central pattern generator neurons in the lobster stomatogastric ganglion

1995 • 47 citations

Cloning of a putative inhibitory amino acid receptor subunit from the parasitic nematode Haemonchus contortus.

1994 • 42 citations

Cloning of a cDNA encoding phosphofructokinase from Haemonchus contortus

1991 • 30 citations

Ivermectin-moxidectin side resistance by Ostertagia species isolated from goats and passaged to sheep

1996 • 26 citations

The glutamate-induced chloride current in Aplysia neurones lacks pharmacological properties seen for excitatory responses to glutamate

1988 • 24 citations

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