Beta-tubulin gene polymorphism and benzimidazole resistance in Trichostrongylus colubriformis

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

The Nematode Caenorhabditis elegans

1988 • 2,868 citations

Rapid transfer of DNA from agarose gels to nylon membranes

1985 • 1,810 citations

The role of the cytoskeletal protein, tubulin, in the mode of action and mechanism of drug resistance to benzimidazoles

1988 • 548 citations

Worm control and anthelmintic resistance: adventures with a model

1995 • 369 citations

Genetic and molecular analysis of a Caenorhabditis elegans beta-tubulin that conveys benzimidazole sensitivity.

1989 • 253 citations

Detecting benzimidazole resistance with faecal egg count reduction tests and in vitro assays

1989 • 217 citations

Resistance of parasites to antiparasitic drugs

1992 • 149 citations

Genetic variability of the beta-tubulin genes in benzimidazole-susceptible and -resistant strains of Haemonchus contortus.

1994 • 148 citations

Effect of Selection for Benzimidazole Resistance in Haemonchus contortus on β-Tubulin Isotype 1 and Isotype 2 Genes

1993 • 139 citations

Interaction of benzimidazole anthelmintics with Haemonchus contortus tubulin: Binding affinity and anthelmintic efficacy

1991 • 131 citations

Resistance in Nematodes to Anthelmintic Drugs

1987 • 130 citations

Interactions of benzimidazoles (BZ) with tubulin from BZ-sensitive and BZ-resistant isolates of Haemonchus contortus

1986 • 118 citations

Molecular analysis of selection for benzimidazole resistance in the sheep parasite Haemonchus contortus

1990 • 118 citations

Molecular characterisation of β-tubulin genes present in benzimidazole-resistant populations of Haemonchus contortus

1993 • 111 citations

New genetic and practical implications of selection for anthelmintic resistance in parasitic nematodes

1995 • 109 citations

Biochemistry of benzimidazole resistance

1994 • 104 citations

Comparison of inhibition of polymerisation of mammalian tubulin and helminth ovicidal activity by benzimidazole carbamates

1987 • 97 citations

Population dynamics of Trichostrongylus colubriformis in sheep: Computer model to simulate grazing systems and the evolution of anthelmintie resistancE

1990 • 90 citations

The inheritance of thiabendazole resistance in Haemonchus contortus

1979 • 76 citations

The molecular nature of benzimidazole resistance in helminths

1990 • 59 citations

Selection studies on anthelmintic resistant and susceptible populations of Trichostrongylus colubriformis of sheep

1985 • 58 citations

A possible biochemical mode of action for benzimidazole anthelmintics

1991 • 56 citations

Beta-tubulin and benzimidazole resistance in the sheep nematode Haemonchus contortus

1991 • 46 citations

Associations between restriction site polymorphism and enzyme activity variation for esterase 6 in Drosophila melanogaster.

1990 • 37 citations

Patterns of naturally occurring restriction map variation, dopa decarboxylase activity variation and linkage disequilibrium in the Ddc gene region of Drosophila melanogaster.

1992 • 32 citations

The inheritance of thiabendazole resistance in Trichostrongylus colubriformis

1988 • 31 citations

Inheritance of cambendazole resistance in Haemonchus contortus.

1981 • 30 citations

Resistance in nematode parasites of livestock to the benzimidazole anthelmintics

1990 • 29 citations

Changes in resistance of Ostertagia spp. to thiabendazole following natural selection or treatment with levamisole

1988 • 28 citations

Transformation of Caenorhabditis elegans with genes from parasitic nematodes

1992 • 27 citations

Further investigations of the primary mechanism of benzimidazole resistance in Haemonchus contortus

1987 • 23 citations

The genetics of resistance to chemotherapeutic agents.

1985 • 18 citations

Extensive DNA polymorphism within and between two strains of Trichostrongylus colubriformis

1994 • 18 citations

Temperature dependent binding of mebendazole to tubulin in benzimidazole-susceptible and -resistant strains of Trichostrongylus colubriformis and Caenorhabditis elegans

1991 • 9 citations

Differential stability of the benzimidazole (BZ)-tubulin complex in BZ-resistant and BZ-susceptible isolates of Haemonchus contortus and Trichostrongylus colubriformis

1992 • 7 citations

Genetic aspects of anthelmintic resistance in nematodes.

1985 • 6 citations

Ecological genetics of anthelmintic resistance.

1990 • 6 citations