Increased IL-6 and TGF-β1 concentrations in bronchoalveolar lavage fluid associated with thoracic radiotherapy

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1999 • 3,154 citations

Interleukin-6: An Overview

1990 • 1,910 citations

Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis.

1991 • 794 citations

A perpetual cascade of cytokines postirradiation leads to pulmonary fibrosis

1995 • 641 citations

Cytokine Balance in the Lungs of Patients with Acute Respiratory Distress Syndrome

2001 • 541 citations

Increased Production and Immunohistochemical Localization of Transforming Growth Factor-α in Idiopathic Pulmonary Fibrosis

1991 • 511 citations

Acute Exacerbations of Chronic Obstructive Pulmonary Disease Are Accompanied by Elevations of Plasma Fibrinogen and Serum IL-6 Levels

2000 • 446 citations

Cytokines of the Lung

1990 • 443 citations

Proinflammatory cytokines (IL-17, IL-6, IL-18 and IL-12) and Th cytokines (IFN-γ, IL-4, IL-10 and IL-13) in patients with allergic asthma

2001 • 430 citations

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1992 • 355 citations

TGF-beta 1, but not TGF-beta 2 or TGF-beta 3, is differentially present in epithelial cells of advanced pulmonary fibrosis: an immunohistochemical study.

1996 • 326 citations

Dose-volume histogram and 3-D treatment planning evaluation of patients with pneumonitis

1994 • 278 citations

Dose-dependent induction of transforming growth factor β (TGF-β) in the lung tissue of fibrosis-prone mice after thoracic irradiation

2000 • 267 citations

Infections and the Inflammatory Response in Acute Respiratory Distress Syndrome

1997 • 259 citations

Radiation pneumonitis following combined modality therapy for lung cancer: analysis of prognostic factors.

1995 • 256 citations

Plasma transforming growth factor β1 as a predictor of radiation pneumonitis

1998 • 236 citations

Radiation pneumonitis and early circulatory cytokine markers

2002 • 230 citations

Bronchoalveolar and systemic cytokine profiles in patients with ARDS, severe pneumonia and cardiogenic pulmonary oedema

1996 • 222 citations

Interleukin-6 and its relation to inflammation and disease

1992 • 214 citations

Early alterations in extracellular matrix and transforming growth factor β gene expression in mouse lung indicative of late radiation fibrosis

1994 • 207 citations

Transforming growth factor beta (TGF-β) and obliterative bronchiolitis following pulmonary transplantation

1999 • 175 citations

Alveolar type II epithelial cells produce interleukin-6 in vitro and in vivo. Regulation by alveolar macrophage secretory products.

1994 • 173 citations

Serum levels of interleukin 6 in patients with lung cancer

1995 • 169 citations

Predicting the risk of symptomatic radiation-induced lung injury using both the physical and biologic parameters V30 and transforming growth factor β

2001 • 162 citations

Local control in medically inoperable lung cancer: An analysis of its importance in outcome and factors determining the probability of tumor eradication

1993 • 162 citations

Circulating IL-6 as a predictor of radiation pneumonitis

2001 • 157 citations

Plasma transforming growth factor-?1 level before radiotherapy correlates with long term outcome of patients with lung carcinoma

1999 • 132 citations

Immunohistochemical Localization of Transforming Growth Factor β and Tumor Necrosis Factor α in the Lungs of Fibrosis-Prone and "Non-Fibrosing" Mice during the Latent Period and Early Phase after Irradiation

1997 • 120 citations

Balance between alveolar macrophage IL-6 and TGF-beta in lung-transplant recipients. Marseille and Montréal Lung Transplantation Group.

1996 • 106 citations

Differences in Correlation of mRNA Gene Expression in Mice Sensitive and Resistant to Radiation-Induced Pulmonary Fibrosis

1995 • 103 citations

Transforming growth factor-beta (TGF-beta) in silicosis.

1996 • 99 citations

TGF-beta1-mediated alterations of rat lung fibroblast differentiation resulting in the radiation-induced fibrotic phenotype

2000 • 95 citations

Eosinophilic Granulocytes and Interleukin-6 Level in Bronchoalveolar Lavage Fluid Are Associated with the Development of Obliterative Bronchiolitis after Lung Transplantation

2000 • 84 citations

Plasma transforming growth factor-β1 reflects disease status in patients with lung cancer after radiotherapy: a possible tumor marker

1996 • 81 citations

Using Plasma Transforming Growth Factor Beta-1 During Radiotherapy to Select Patients for Dose Escalation

2001 • 80 citations

Transforming growth factor-beta regulation of IL-6 production by unstimulated and IL-1-stimulated human fibroblasts.

1991 • 80 citations

Increased Levels of Interleukin-6 Are Associated with Lymphocytosis in Bronchoalveolar Lavage Fluids of Idiopathic Nonspecific Interstitial Pneumonia

2000 • 69 citations

Normal tissue injury after cancer therapy is a local response exacerbated by an endocrine effect of TGFβ

1995 • 67 citations

Radiation-induced lung injury in vivo: Expression of transforming growth factor?Beta precedes fibrosis

1996 • 66 citations

Induction of interleukin‐1β and interleukin‐6 mRNA by low doses of ionizing radiation in macrophages

2001 • 58 citations

The relevance of transforming growth factor β1 in pulmonary injury after radiation therapy

1998 • 58 citations

Interleukin 6 secretion by monocytes and alveolar macrophages in systemic sclerosis with lung involvement.

1994 • 47 citations

Expression of pro-inflammatory cytokines by flow-sorted alveolar macrophages in severe pneumonia

1998 • 45 citations

Increased TGFβ₁ plasma level in patients with lung cancer: potential mechanisms

2002 • 38 citations

Evaluation of interleukin-6 in bronchoalveolar lavage fluid and serum of patients with lung cancer

1999 • 32 citations

Irradiated homozygous TGF- β 1 knockout fibroblasts show enhanced clonogenic survival as compared with TGF- β 1 wild-type fibroblasts

2002 • 32 citations

Interleukin-6 in bronchoalveolar lavage fluid from patients with COPD.

2001 • 30 citations

Serum interleukin-6 and tumor necrosis factor-alpha concentrations in children with mycoplasma pneumonia.

2001 • 27 citations

Elevated plasma endothelin-1 and cytokine levels in children with severe acute respiratory distress syndrome

1999 • 23 citations

Differences in arterial and mixed venous IL-6 levels: The lungs as a source of cytokine storm in sepsis

2001 • 19 citations

TNF-alpha, IL-1 and IL-6 concentration in bronchoalveolar lavage fluid (BALF) of non-small cell lung cancer (NSCLC).

1997 • 12 citations