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Methylprednisolone After Split-course Chemoradiotherapy For Bulky Local Advanced None-small Cell Lung Cancer
NCT03661567
PHASE2INTERVENTIONAL
Sun Yat-sen University
52 participants
Started 2018-08-09 · Completed 2021-09-10
Status: Terminated (as of 12-23-2025)
Conditions
Non-small Cell Lung Cancer
Linked Papers (from SciSciNet-V2)
Total Papers16
Background
6Result
0Derived
0Unknown
10Total Citations Per Year
Brief Summary
This Phase II randomized controlled study is to determine the efficacy of the preventively use of methylprednisolone after split-course chemoradiotherapy (CCRT) in locally advanced non-small cell lung cancer with bulky tumor.
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Background Papers12
Radiation Dose–Volume Effects in the Lung
2010
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Radiation Dose–Volume Effects in the Lung
2010
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A literature-based meta-analysis of clinical risk factors for development of radiation induced pneumonitis
2012
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A literature-based meta-analysis of clinical risk factors for development of radiation induced pneumonitis
2012
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Immunological Aspect of Radiation-Induced Pneumonitis, Current Treatment Strategies, and Future Prospects
2017
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Immunological Aspect of Radiation-Induced Pneumonitis, Current Treatment Strategies, and Future Prospects
2017
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Expression of Interleukin-17A in Lung Tissues of Irradiated Mice and the Influence of Dexamethasone
2014
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Expression of Interleukin-17A in Lung Tissues of Irradiated Mice and the Influence of Dexamethasone
2014
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Dosimetric comparison between IMRT and VMAT in irradiation for peripheral and central lung cancer
2018
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Dosimetric comparison between IMRT and VMAT in irradiation for peripheral and central lung cancer
2018
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Corticosteroid therapy against treatment-related pulmonary toxicities in patients with lung cancer.
2014
15 citations
Corticosteroid therapy against treatment-related pulmonary toxicities in patients with lung cancer.
2014
15 citations
Result Papers0
No result papers linked
Derived Papers0
No derived papers linked
Unknown Papers10
Dose and volume reduction for normal lung using intensity-modulated radiotherapy for advanced-stage non–small-cell lung cancer
2004
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Radiation Pneumonitis: A Possible Lymphocyte-mediated Hypersensitivity Reaction
1993
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Radiation pneumonitis in lung cancer patients: a retrospective study of risk factors and the long-term prognosis
2001
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Target cells in radiation pneumopathy
2004
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Radiation Induced Lung Injury: Prediction, Assessment and Management
2015
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Increased IL-6 and TGF-β1 concentrations in bronchoalveolar lavage fluid associated with thoracic radiotherapy
2004
88 citations
Retrospective analysis of steroid therapy for radiation-induced lung injury in lung cancer patients
2006
64 citations
Role of Adaptive Radiotherapy During Concomitant Chemoradiotherapy for Lung Cancer: Analysis of Data From a Prospective Clinical Trial
2009
33 citations
Split-Course Chemoradiotherapy for Locally Advanced Non-small Cell Lung Cancer: A Single-Institution Experience of 144 Patients
2011
18 citations
Pneumopathie post-radique aiguë : une pneumopathie rare, potentiellement grave et très corticosensible
2010
1 citations