Chlamydia trachomatis-Specific Human CD8⁺T Cells Show Two Patterns of Antigen Recognition

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

Antigen Presentation and T Cell Stimulation by Dendritic Cells

2002 • 1,860 citations

Relationship between interferon‐γ, indoleamine 2,3‐dioxygenase, and tryptophan catabolism

1991 • 1,018 citations

THE CD1 SYSTEM: Antigen-Presenting Molecules for T Cell Recognition of Lipids and Glycolipids

1999 • 711 citations

Inhibition of Apoptosis in Chlamydia-infected Cells: Blockade of Mitochondrial Cytochrome c Release and Caspase Activation

1998 • 586 citations

Tryptophan depletion as a mechanism of gamma interferon-mediated chlamydial persistence

1994 • 326 citations

Mapping antigenic domains expressed by Chlamydia trachomatis major outer membrane protein genes.

1988 • 323 citations

CD4+ T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract

1995 • 263 citations

Dissemination of Chlamydia trachomatis chronic genital tract infection in gamma interferon gene knockout mice

1997 • 254 citations

CD1-dependent dendritic cell instruction

2002 • 215 citations

Genital tract infection with Chlamydia trachomatis fails to induce protective immunity in gamma interferon receptor-deficient mice despite a strong local immunoglobulin A response

1997 • 204 citations

Role of tryptophan degradation in respiratory burst-independent antimicrobial activity of gamma interferon-stimulated human macrophages

1989 • 201 citations

T Cell Responses to Gram-Negative Intracellular Bacterial Pathogens: A Role for CD8+ T Cells in Immunity toSalmonellaInfection and the Involvement of MHC Class Ib Molecules

1999 • 169 citations

Protective cytotoxic T lymphocytes are induced during murine infection with Chlamydia trachomatis.

1994 • 167 citations

The Epidemiology of Chlamydia trachomatis within a Sexually Transmitted Diseases Core Group

1996 • 151 citations

Gamma-interferon is the factor in lymphokine that activates human macrophages to inhibit intracellular Chlamydia psittaci replication.

1983 • 139 citations

Characterization of CD8+ Effector T Cell Responses in Volunteers Immunized with Salmonella enterica Serovar Typhi Strain Ty21a Typhoid Vaccine

2002 • 137 citations

Resolution of chlamydial genital infection with antigen-specific T-lymphocyte lines

1991 • 135 citations

CD8⁺T cells recognize an inclusion membrane-associated protein from the vacuolar pathogenChlamydia trachomatis

2001 • 130 citations

T cell responses to Chlamydia trachomatis

2002 • 126 citations

Protective cytotoxic T lymphocytes are induced during murine infection with Chlamydia trachomatis.

1994 • 126 citations

An Inclusion Membrane Protein from Chlamydia trachomatis Enters the MHC Class I Pathway and Stimulates a CD8+ T Cell Response

2003 • 104 citations

Gamma Interferon Production by Cytotoxic T Lymphocytes Is Required for Resolution ofChlamydia trachomatisInfection

1998 • 101 citations

Classically Restricted Human CD8+ T Lymphocytes Derived fromMycobacterium tuberculosis-Infected Cells: Definition of Antigenic Specificity

2001 • 95 citations

Inhibition ofChlamydia pneumoniaeReplication in HEp‐2 Cells by Interferon‐g: Role of Tryptophan Catabolism

1998 • 90 citations

Differential Sensitivities ofChlamydia trachomatisStrains to Inhibitory Effects of Gamma Interferon

2000 • 85 citations

Chlamydia and associated arthritis

2000 • 82 citations

Studies in Knockout Mice Reveal that Anti‐Chlamydial Protection Requires TH1 Cells Producing IFN‐γ: Is this True for Humans?

1997 • 77 citations

Direct Detection and Magnetic Isolation ofChlamydia trachomatisMajor Outer Membrane Protein-Specific CD8+ CTLs with HLA Class I Tetramers

2000 • 73 citations

Induction of HLA Class I-Restricted CD8+ CTLs Specific for the Major Outer Membrane Protein of Chlamydia trachomatis in Human Genital Tract Infections

1999 • 73 citations

Chlamydia trachomatis major outer membrane protein (MOMP) epitopes that activate HLA class II-restricted T cells from infected humans.

1996 • 73 citations

T lymphocyte dynamics during Listeria monocytogenes infection

1999 • 65 citations

The quantity of nitric oxide released by macrophages regulatesChlamydia-induced disease

2002 • 65 citations

The human macrophage cell line U937 as an in vitro model for selective evaluation of mycobacterial antigen‐specific cytotoxic T‐cell function

2001 • 63 citations

Identification of Chlamydia trachomatis antigens recognized by human CD4+ T lymphocytes by screening an expression library

2001 • 62 citations

Presentation of self and microbial lipids by CD1 molecules

2001 • 62 citations

The molecular mechanism of T-cell control of Chlamydia in mice: role of nitric oxide.

1996 • 61 citations

Epidemiology of Ocular Chlamydial Infection in a Trachoma-Hyperendemic Area

1991 • 58 citations

Uptake and processing of Chlamydia trachomatis by human dendritic cells

2002 • 58 citations

Molecular mechanism of T‐cell control of Chlamydia in mice: role of nitric oxide in vivo

1996 • 53 citations

T-Cell Epitopes in Variable Segments ofChlamydia trachomatisMajor Outer Membrane Protein Elicit Serovar-Specific Immune Responses in Infected Humans

2000 • 50 citations

Identification and characterization of a DR4-restricted T cell epitope within chlamydia heat shock protein 60

1997 • 48 citations

Update on Chlamydia trachomatis

2000 • 47 citations

Effect of interferon on a primary conjunctival epithelial cell model of trachoma.

1991 • 41 citations

MHC class I restricted T cell responses tolisteria monocytogenes, an intracellular bacterial pathogen

1999 • 39 citations

Reactive arthritis

2000 • 36 citations

Activation of mouse peritoneal macrophages in vitro or in vivo by recombinant murine gamma interferon inhibits the growth of Chlamydia trachomatis serovar L1

1988 • 36 citations

Recognition of the 60 kilodalton cysteine-rich outer membrane protein OMP2 by CD4+ T cells from humans infected withChlamydia trachomatis

2001 • 35 citations

Synthetic peptides based on Chlamydia trachomatis antigens identify cytotoxic T lymphocyte responses in subjects from a trachoma-endemic population

1997 • 34 citations

Hereditary Vascular Dementia Linked to Notch 3 Mutations: CADASIL in British Families

2000 • 34 citations

Recognition of chlamydial antigen by HLA‐B27‐restricted cytotoxic T cells in HLA‐B*2705 transgenic CBA (H‐2^k) mice

1997 • 30 citations

Immunological basis of chlamydia induced reactive arthritis

2000 • 27 citations

Functional Characterization of Class Ia- and Non-Class Ia-RestrictedChlamydia-Reactive CD8+ T Cell Responses in Humans

2003 • 24 citations

The resistance of human monocyte‐derived macrophages to Chlamydia pneumoniae infection is enhanced by interferon‐gamma

2000 • 15 citations

Clearance of Chlamydia trachomatis - induced polyserositis in SCID mice requires both CD4 + and CD8 + cells

1998 • 11 citations

Isolation and characterisation of T lymphocytes from the urethra of patients with acute urethritis.

1998 • 8 citations