Identification of Chlamydia trachomatis antigens recognized by human CD4+ T lymphocytes by screening an expression library

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1997 • 71,835 citations

Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis

1998 • 1,548 citations

Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis

1981 • 1,054 citations

Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-gamma-dependent and -independent pathways.

1997 • 365 citations

Gene knockout mice establish a primary protective role for major histocompatibility complex class II-restricted responses in Chlamydia trachomatis genital tract infection

1995 • 333 citations

CD4+ T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract

1995 • 263 citations

Dissemination of Chlamydia trachomatis chronic genital tract infection in gamma interferon gene knockout mice

1997 • 254 citations

Mouse strain-dependent variation in the course and outcome of chlamydial genital tract infection is associated with differences in host response

1997 • 189 citations

Crucial role of interleukin‐10/interleukin‐12 balance in the regulation of the type 2 T helper cytokine response in reactive arthritis

1997 • 173 citations

Identification and characterization of a Chlamydia trachomatis early operon encoding four novel inclusion membrane proteins

1999 • 172 citations

Local Th1-like responses are induced by intravaginal infection of mice with the mouse pneumonitis biovar of Chlamydia trachomatis

1995 • 139 citations

Analysis of the cellular infiltrates and expression of cytokines in synovial tissue from patients with rheumatoid arthritis and reactive arthritis

1998 • 137 citations

Expression Cloning of an Immunodominant Family of Mycobacterium tuberculosis Antigens Using Human Cd4+ T Cells

2000 • 123 citations

Differential sensitivity of distinct Chlamydia trachomatis isolates to IFN-gamma-mediated inhibition.

1999 • 117 citations

Computational Analysis of the Polymorphic Membrane Protein Superfamily ofChlamydia trachomatisandChlamydia pneumoniae

1999 • 105 citations

Initial route of antigen administration alters the T-cell cytokine profile produced in response to the mouse pneumonitis biovar of Chlamydia trachomatis following genital infection

1996 • 93 citations

Interleukin-12 Production Is Required for Chlamydial Antigen-Pulsed Dendritic Cells To Induce Protection against Live Chlamydia trachomatis Infection

1999 • 91 citations

Humoral and cellular immunity in secondary infection due to murine Chlamydia trachomatis

1997 • 89 citations

Predominance of T_h1‐type T cells in synovial fluid of patients with Yersinia‐induced reactive arthritis

1992 • 86 citations

Development of a quantitative gene expression assay for Chlamydia trachomatis identified temporal expression of σ factors

1999 • 81 citations

Type III machines of pathogenic yersiniae secrete virulence factors into the extracellular milieu

1999 • 81 citations

Role of Gamma Interferon in Controlling Murine Chlamydial Genital Tract Infection

1999 • 79 citations

Chlamydia trachomatis major outer membrane protein (MOMP) epitopes that activate HLA class II-restricted T cells from infected humans.

1996 • 73 citations

Identification of a CD4+ T cell-stimulating antigen of pathogenic bacteria by expression cloning.

1995 • 69 citations

Trachoma vaccine field trials in The Gambia

1969 • 66 citations

Evidence for a predominant proinflammatory conjunctival cytokine response in individuals with trachoma

1996 • 65 citations

Recombinant Escherichia coli express a defined, cytoplasmic epitope that is efficiently processed in macrophage phagolysosomes for class II MHC presentation to T lymphocytes.

1992 • 59 citations

Analysis of Lymphocyte Phenotype and Cytokine Activity in the Inflammatory Infiltrates of the Upper Genital Tract of Female Macaques Infected with Chlamydia trachomatis

1996 • 58 citations

Use of a Mouse Lung Challenge Model to Identify Antigens Protective againstChlamydia pneumoniaeLung Infection

2000 • 55 citations

Role of L3T4-bearing T-cell populations in experimental murine chlamydial salpingitis

1991 • 54 citations

Cloning and expression of a Leishmania donovani gene instructed by a peptide isolated from major histocompatibility complex class II molecules of infected macrophages.

1995 • 53 citations

Identification and characterization of a DR4-restricted T cell epitope within chlamydia heat shock protein 60

1997 • 48 citations

Chlamydial Genomics and Vaccine Antigen Discovery

2000 • 47 citations

Pathogenesis of Chlamydial Infections

1989 • 46 citations

Prospects for a vaccine against Chlamydia genital disease I. — Microbiology and pathogenesis

1996 • 45 citations

Reactive or infectious arthritis

1999 • 44 citations

Immunity toChlamydia trachomatisMouse Pneumonitis Induced by Vaccination with Live Organisms Correlates with Early Granulocyte-Macrophage Colony-Stimulating Factor and Interleukin-12 Production and with Dendritic Cell-Like Maturation

1999 • 40 citations

Identification of T-cell stimulatory antigens of Chlamydia trachomatis using synovial fluid-derived T-cell clones.

1993 • 34 citations

Human γδ T‐cell recognition of Yersinia enterocolitica

1997 • 26 citations

Comparison of Outer Membrane Protein Genesompandpmpin the Whole Genome Sequences ofChlamydia pneumoniaeIsolates from Japan and the United States

2000 • 26 citations

Potential Relevance ofChlamydia pneumoniaeSurface Proteins to an Effective Vaccine

2000 • 25 citations

Rheumatologic manifestations of gastrointestinal disorders

1999 • 25 citations

Prospects for a vaccine against Chlamydia genital disease II. — Immunity and vaccine development

1996 • 24 citations

Use of a primate model system to identify Chlamydia trachomatis protein antigens recognized uniquely in the context of infection

1999 • 23 citations

Generation of a highly immunogenic recombinant enolase of the human opportunistic pathogen Candida albicans

1999 • 22 citations

Molecular cloning of the major outer membrane protein of Chlamydia trachomatis

1984 • 18 citations

Effects of interferon gamma onChlamydia trachomatis serovar A and L2 protein expression investigated by two-dimensional gel electrophoresis

1999 • 16 citations

Interleukin-12 Production Is Required for Chlamydial Antigen-Pulsed Dendritic Cells To Induce Protection against Live Chlamydia trachomatis Infection

1999 • 12 citations

Immunity to Chlamydia trachomatis Mouse Pneumonitis Induced by Vaccination with Live Organisms Correlates with Early Granulocyte-Macrophage Colony-Stimulating Factor and Interleukin-12 Production and with Dendritic Cell-Like Maturation

1999 • 10 citations

Effects of interferon gamma on Chlamydia trachomatis serovar A and L2 protein expression investigated by two-dimensional gel electrophoresis

1999 • 1 citations