Physiological Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

Dementia Praecox or the Group of Schizophrenias

1951 • 4,409 citations

Implications of Normal Brain Development for the Pathogenesis of Schizophrenia

1987 • 3,683 citations

Dementia Praecox and Paraphrenia.

1972 • 3,028 citations

INTERHEMISPHERIC DIFFERENCES IN THE LOCALIZATION OF PSYCHOLOGICAL PROCESSES IN MAN

1971 • 2,328 citations

The frontal lobes

1986 • 2,138 citations

Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1986 • 2,026 citations

Cognitive Deficit Caused by Regional Depletion of Dopamine in Prefrontal Cortex of Rhesus Monkey

1979 • 1,496 citations

Regional Cerebral Blood Flow Estimated by ¹³³ Xenon Inhalation

1975 • 866 citations

A BIOCHEMICAL AND PHARMACOLOGICAL SUGGESTION ABOUT CERTAIN MENTAL DISORDERS

1954 • 591 citations

Cerebral Glucography With Positron Tomography

1982 • 538 citations

Further Evidence for Dementia of the Prefrontal Type in Schizophrenia?

1987 • 524 citations

Relationships among local functional activity, energy metabolism, and blood flow in the central nervous system.

1981 • 486 citations

Correlation Between Regional Cerebral Blood Flow and Oxidative Metabolism

1976 • 481 citations

Performance of Schizophrenic Patients on Tests Sensitive To Left or Right Frontal, Temporal, or Parietal Function in Neurological Patients

1983 • 467 citations

Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1986 • 420 citations

Anteroposterior Gradients in Cerebral Glucose Use in Schizophrenia and Affective Disorders

1984 • 376 citations

Persistence of cerebral metabolic abnormalities in chronic schizophrenia as determined by positron emission tomography

1985 • 299 citations

Left globus pallidus abnormality in never-medicated patients with schizophrenia.

1987 • 269 citations

Correlations between aminergic metabolites simultaneously obtained from human CSF and brain

1985 • 248 citations

Simultaneous determination of 3-methoxy-4-hydroxyphenylglycol, 5-hydroxyindoleacetic acid, and homovanillic acid in cerebrospinal fluid with high-performance liquid chromatography using electrochemical detection

1983 • 247 citations

Regional Brain Glucose Metabolism in Chronic Schizophrenia

1984 • 237 citations

Decreased serotonin S2 and increased dopamine D2 receptors in chronic schizophrenics

1986 • 225 citations

Phenomenological correlates of metabolic activity in 18 patients with chronic schizophrenia

1987 • 216 citations

Regional Brain Function in Schizophrenia

1987 • 211 citations

15O POSITRON EMISSION TOMOGRAPHIC SCANNING IN PREDOMINANTLY NEVER-TREATED ACUTE SCHIZOPHRENIC PATIENTS

1983 • 207 citations

Relation Between Plasma and Cerebrospinal Fluid Levels of 3-Methoxy-4-Hydroxyphenylglycol

1983 • 203 citations

Positron emission tomography studies of basal ganglia and somatosensory cortex neuroleptic drug effects: Differences between normal controls and schizophrenic patients

1987 • 185 citations

Dopamine deficiency in the cerebral cortex in Parkinson disease

1982 • 179 citations

Dysfunction in a prefrontal substrate of sustained attention in schizophrenia

1987 • 145 citations

Brain metabolism in patients with schizophrenia before and after acute neuroleptic administration.

1986 • 128 citations

Dopamine-β-Hydroxylase Activity and Homovanillic Acid in Spinal Fluid of Schizophrenics with Brain Atrophy

1983 • 125 citations

Low HVA and normal 5HIAA CSF levels in drug-free schizophrenic patients compared to healthy volunteers: Correlations to symptomatology and family history

1985 • 121 citations

Absence of activation in frontal structures during psychological testing of chronic schizophrenics.

1975 • 116 citations

Changes of cortical activity patterns during habituation to a reasoning test

1977 • 111 citations

The distribution of alterations in energy metabolism in the rat brain produced by apomorphine

1982 • 111 citations

Low CSF 5-hydroxyindoleacetic acid in schizophrenic patients with enlarged cerebral ventricles

1983 • 102 citations

Homovanillic acid concentrations in brain, CSF and plasma as indicators of central dopamine function in primates

1987 • 93 citations

Behavioral Activation and the Variability of Cerebral Glucose Metabolic Measurements

1987 • 91 citations

Prefrontal cortical blood flow and cognitive function in Huntington's disease.

1988 • 87 citations

Measurement of 3-methoxy-4-hydroxyphenylglycol in human plasma with high-performance liquid chromatography using electrochemical detection

1983 • 85 citations

Reversibility of Hemodynamic Hypofrontality in Schizophrenia

1987 • 75 citations

On Frontal Lobe Functions: Psychiatric Patient Controls

1974 • 73 citations

Cerebrospinal fluid: A selective review

1982 • 72 citations

Cerebrospinal fluid HVA, central brain atrophy, and clinical state in schizophrenia

1986 • 72 citations

A relationship between anatomical and physiological brain pathology in schizophrenia: lateral cerebral ventricular size predicts cortical blood flow

1987 • 47 citations

Reliability of Norepinephrine and Major Monoamine Metabolite Measurements in CSF of Schizophrenic Patients

1983 • 47 citations

Correlates of lateral ventricular size in chronic schizophrenia, II: biological measures

1986 • 39 citations

The Neurology of Schizophrenia

1956 • 34 citations

Physiological and Behavioral Analysis of Raphe Unit Activity

1984 • 32 citations

CSF acid monoamine metabolites in psychotic syndromes: what might they signify?

1978 • 27 citations

Phenylethylamine and monoamine metabolites in CSF of schizophrenics: Effects of neuroleptic treatment

1983 • 23 citations

Brain ventricular size and CSF monoamine metabolites in an adolescent inpatient population

1985 • 22 citations

Suppression of serotonin-dependent cerebral activation: a possible mechanism of action of some psychotomimetic drugs

1987 • 16 citations

5-HYDROXYTRYPTOPHAN AND CHRONIC SCHIZOPHRENIA - A PRELIMINARY STUDY

1973 • 8 citations