Suppression of serotonin-dependent cerebral activation: a possible mechanism of action of some psychotomimetic drugs

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

1976 • 2,883 citations

The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N‐methyl‐aspartate

1983 • 1,400 citations

Neurobiology of the hippocampus

1984 • 1,096 citations

Two types of hippocampal rhythmical slow activity in both the rabbit and the rat: Relations to behavior and effects of atropine, diethyl ether, urethane, and pentobarbital

1975 • 765 citations

An animal behavior model for studying central serotonergic synapses

1976 • 555 citations

Mathematics of Statistics.

1940 • 513 citations

Serotonergic facilitation of facial motoneuron excitation

1979 • 440 citations

Reticulo-cortical activity and behavior: A critique of the arousal theory and a new synthesis

1981 • 404 citations

Specific [3H]phencyclidine binding in rat central nervous system.

1979 • 382 citations

Electrical activity of the archicortex

1986 • 346 citations

Serotonin Neurotransmission and Behavior

1982 • 309 citations

Behavioral Pharmacology: The Current Status

1985 • 281 citations

The human pharmacology and abuse potential of N-allylnoroxymorphone (naloxone).

1967 • 278 citations

Cholinergic activation of the electrocorticogram: Role of the substantia innominata and effects of atropine and quinuclidinyl benzilate

1984 • 273 citations

Interaction of phencyclidine ("angel dust") with a specific receptor in rat brain membranes.

1979 • 263 citations

Excitation and depression of cortical neurones by 5‐hydroxytryptamine

1967 • 259 citations

Hippocampal Rhythmic Slow Activity and Neocortical Low-Voltage Fast Activity: Relations to Behavior

1975 • 257 citations

Evidence that serotonin mediates non-cholinergic neocortical low voltage fast activity, non-cholinergic hippocampal rhythmical slow activity and contributes to intelligent behavior

1986 • 255 citations

Effects of phencyclidine on [3H]catecholamine and [3H]serotonin uptake in synaptosomal preparations from rat brain

1977 • 214 citations

Phencyclidine

1980 • 202 citations

Near-total loss of ‘learning’ and ‘memory’ as a result of combined cholinergic and serotonergic blockade in the rat

1987 • 175 citations

(+)-[3H]SKF 10,047, (+)-[3H]ethylketocyclazocine, μ, κ, δ and phencyclidine binding sites in guinea pig brain membranes

1985 • 168 citations

Antidepressants: Neurochemical, Behavioral and Clinical Perspectives

1982 • 162 citations

Two types of cerebral activation during active sleep: relations to behavior

1977 • 152 citations

Demonstration of [3H]cyclazocine binding to multiple opiate receptor sites.

1981 • 151 citations

Hippocampal Electrical Activity During Waking Behaviour and Sleep: Analyses using Centrally Acting Drugs

1978 • 137 citations

Neurobiology of the Trace Amines

1984 • 131 citations

The responses of cortical neurones to monoamines under differing anaesthetic conditions

1969 • 126 citations

Subjective effects of narcotic antagonists cyclazocine and nalorphine on the Addiction Research Center Inventory (ARCI)

1970 • 124 citations

Phencyclidine and σ opiate receptors in brain: Biochemical and autoradiographical differentiation

1985 • 124 citations

[3H]Thienyl-phencyclidine ([3H]TCP) binds to two different sites in rat brain. Localization by autoradiographic and biochemical techniques

1986 • 116 citations

Behavior-dependent evoked potentials in the hippocampal CA1 region of the rat. II. Effect of eserine, atropine, ether and pentobarbital

1980 • 99 citations

Narcotic Antagonists as Analgesics

1962 • 95 citations

Phencyclidine receptors in rat brain cortex

1984 • 88 citations

The phencyclidine psychosis: phenomenology and treatment.

1978 • 64 citations

Molecular Modification in Drug Design.

1965 • 60 citations

Construction of wire leads and electrodes for use in slow wave recording in small animals

1978 • 59 citations

Reserpine Abolishes Movement-correlated atropine-resistant neocortical low voltage fast activity

1980 • 58 citations

Ketamine inhibits serotonin uptake in vivo

1982 • 58 citations

Pharmacology of theta phase shift in the hippocampal CA1 region of freely moving rats

1984 • 58 citations

Functions of the Septo-Hippocampal System. Ciba Foundation Symposium 58

1979 • 57 citations

Mathematics for Statistics

1973 • 57 citations

The action of certain cyclothexamines on hippocampal system during approach performance in the cat.

1960 • 46 citations

Monoamine replacement after reserpine: catecholaminergic agonists restore motor activity but phenylethylamine restores atropine-resistant neocortical low voltage fast activity.

1980 • 42 citations

Joint cholinergic-serotonergic control of neocortical and hippocampal electrical activity in relation to behavior: Effects of scopolamine, ditran, trifluoperazine and amphetamine

1986 • 40 citations

Monoamine replacement after reserpine: Catecholaminergic agonists restore motor activity but phenylethylamine restores atropine-resistant neocortical low voltage fast activity

1980 • 40 citations

Ketamine — “Dissociative Agent” or Hallucinogen?

1971 • 37 citations

Ketamine inhibits serotonin synthesis and metabolism in vivo

1982 • 36 citations

Hippocampal EEG and motor activity in the cat: The role of eye movements and body acceleration

1984 • 35 citations

Physiological and Behavioral Analysis of Raphe Unit Activity

1984 • 32 citations

Phencyclidine (PCP) Abuse: An Appraisal. NIDA Research Monograph 21

1979 • 28 citations

Acute and chronic phencyclidine administration changes serotonin receptors in rat brain

1985 • 27 citations

Aminergic Control of the Electrocorticogram: A Progress Report

1984 • 23 citations

Effects of acute and chronic administrations of phencyclidine on the levels of serotonin and 5-hydroxyindoleacetic acid in discrete brain areas of mouse

1985 • 18 citations

Neurochemical pharmacology of phencyclidine.

1978 • 16 citations

Hypothalamic self-stimulation: The role of dopamine and possible relations to neocortical slow wave activity

1984 • 14 citations

PHENCYCLIDINE‐LIKE DISCRIMINATIVE STIMULUS PROPERTIES OF PSYCHOTOMIMETIC OPIOIDS *

1982 • 11 citations