Postnatal environment overrides genetic and prenatal factors influencing offspring obesity and insulin resistance

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1999 • 5,310 citations

Maternal Care, Gene Expression, and the Transmission of Individual Differences in Stress Reactivity Across Generations

2001 • 2,665 citations

Role of Brain Insulin Receptor in Control of Body Weight and Reproduction

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Isolated removal of hypothalamic or other brain nuclei of the rat

1973 • 1,421 citations

Trophic Action of Leptin on Hypothalamic Neurons That Regulate Feeding

2004 • 1,188 citations

Rapid Rewiring of Arcuate Nucleus Feeding Circuits by Leptin

2004 • 975 citations

American Physiological Society

1922 • 803 citations

Formation of Projection Pathways from the Arcuate Nucleus of the Hypothalamus to Hypothalamic Regions Implicated in the Neural Control of Feeding Behavior in Mice

2004 • 565 citations

Neuropeptide Y: A potent inducer of consummatory behavior in rats

1984 • 564 citations

Selective breeding for diet-induced obesity and resistance in Sprague-Dawley rats

1997 • 522 citations

Guiding principles for research involving animals and human beings

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The hypothalamic arcuate nucleus: A key site for mediating leptin’s effects on glucose homeostasis and locomotor activity

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Hormones and Growth Factors in Milk

1993 • 399 citations

Local Ventromedial Hypothalamus Glucopenia Triggers Counterregulatory Hormone Release

1995 • 372 citations

Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats.

1997 • 357 citations

Longchain polyunsaturated fatty acid supplementation in preterm infants

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Dietary essential fatty acids and brain function: a developmental perspective on mechanisms

2002 • 339 citations

Central melanocortin receptors regulate insulin action

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Regulation of Neuronal and Glial Proteins by Leptin: Implications for Brain Development*

1999 • 320 citations

Central melanocortin receptors regulate insulin action

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Development of Hypertension in a Rat Model of Diet-Induced Obesity

2000 • 312 citations

Physiological and Molecular Characteristics of Rat Hypothalamic Ventromedial Nucleus Glucosensing Neurons

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Topographic mapping of VMH → arcuate nucleus microcircuits and their reorganization by fasting

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Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons

2005 • 285 citations

Effects of dietary fat types on body fatness, leptin, and ARC leptin receptor, NPY, and AgRP mRNA expression

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Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling before obesity onset

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The Regulation of Glucose-Excited Neurons in the Hypothalamic Arcuate Nucleus by Glucose and Feeding-Relevant Peptides

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Essential fatty acids, DHA and human brain

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High-fat feeding during pregnancy and lactation affects offspring metabolism in rats

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Genetics of Obesity

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THE DEVELOPMENT WITH AGE OF HYPOTHALAMIC RESTRAINT UPON THE APPETITE OF THE RAT

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Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice

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n-3 long chain polyunsaturated fatty acids: a nutritional tool to prevent insulin resistance associated to type 2 diabetes and obesity?

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Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone.

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Gestational obesity accentuates obesity in obesity-prone progeny

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Maternal Environment and Genotype Interact to Establish Diabesity in Mice

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Long-Term Effects of Early Nutritional Experience on the Development of Obesity in the Rat

1980 • 150 citations

Abnormalities of leptin and ghrelin regulation in obesity-prone juvenile rats

2003 • 139 citations

Differential effects of dietary saturated and trans-fatty acids on expression of genes associated with insulin sensitivity in rat adipose tissue

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Postnatal development of the hypothalamic neuropeptide Y system

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Variations of maternal care differentially influence ‘fear’ reactivity and regional patterns of cFos immunoreactivity in response to the shock-probe burying test

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Effect of Early Nutrition on Adipose Cellularity and Pancreatic Insulin Release in the Zucker Rat

1973 • 120 citations

Trophic effects of insulin-like growth factor-I on fetal rat hypothalamic cells in culture

1990 • 109 citations

Ontogeny of diet-induced obesity in selectively bred Sprague-Dawley rats

2003 • 108 citations

Cross-Fostering to Diabetic Rat Dams Affects Early Development of Mediobasal Hypothalamic Nuclei Regulating Food Intake, Body Weight, and Metabolism

2004 • 102 citations

Leptin levels in rat offspring are modified by the ratio of linoleic to α-linolenic acid in the maternal diet

2002 • 100 citations

Morphological alterations of hypothalamic nucleidue to intrahypothalamic hyperinsulinism in newborn rats

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Lactation in lean and obese rats: Effect of cafeteria feeding and of dietary obesity on milk composition

1986 • 89 citations

Maternal milk and plasma glucose and insulin levels: studies in normal and diabetic subjects.

1989 • 84 citations

Duration of long-chain polyunsaturated fatty acids availability in the diet and visual acuity

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Postnatal development of catecholamine inputs to the paraventricular nucleus of the hypothalamus in rats

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The early intracellular signaling pathway for the insulin/insulin-like growth factor receptor family in the mammalian central nervous system

1996 • 75 citations

Syndrome X-like alterations in adult female rats due to neonatal insulin treatment

1998 • 71 citations

Maternal behavior regulates long‐term hippocampal expression of BAX and apoptosis in the offspring

2002 • 66 citations

Development and Characterization of a Purified Diet to Identify Obesity-Susceptible and Resistant Rat Populations

1994 • 65 citations

Longchain polyunsaturated fatty acid supplementation in preterm infants

2004 • 62 citations

Postnatal development of hypothalamic inputs to the dorsal vagal complex in rats

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F-DIO obesity-prone rat is insulin resistant before obesity onset

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Time course of short-term and long-term orexigenic effects of Agouti-related protein (86-132)

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Catecholamine levels in discrete brain nuclei of seven month old genetically obese rats

1979 • 51 citations

Modifying the n−3 fatty acid content of the maternal diet to determine the requirements of the fetal and suckling rat

1997 • 49 citations

Stimulation of Peroxisome Proliferator-Activated Receptors α and γ Blocks HIV-1 Replication and TNFα Production in Acutely Infected Primary Blood Cells, Chronically Infected U1 Cells, and Alveolar Macrophages From HIV-Infected Subjects

2002 • 49 citations

Changes in lipid metabolism in diet-induced obesity

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Nutritional effects on auditory brainstem maturation in healthy term infants

2004 • 43 citations

Hypothalamic Gene Expression Is Altered in Underweight but Obese Juvenile Male Sprague-Dawley Rats Fed a High-Energy Diet

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Maternal obesity alters adiposity and monoamine function in genetically predisposed offspring

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Cellular Aspects of Trophic Actions in the Nervous System

1999 • 40 citations

Regulation of growth-associated protein 43 (GAP-43) messenger RNA associated with plastic change in the adult rat barrel receptor complex

1993 • 39 citations

GLUT-4, tumor necrosis factor, essential fatty acids and daf-genes and their role in insulin resistance and non-insulin dependent diabetes melltinus

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Projection of pro-opiomelanocortin neurons from the rat arcuate nucleus to the midbrain central gray as demonstrated by double staining with retrograde labeling and immunohistochemistry.

1988 • 31 citations

Maternal Dietary Intake of Essential Fatty Acids Affects Adipose Tissue Growth and Leptin mRNA Expression in Suckling Rat Pups

2002 • 26 citations

Plasticity of Brain α‐Adrenoceptors During the Development of Diet‐Induced Obesity in the Rat

1994 • 23 citations

Longchain polyunsaturated fatty acid supplementation in preterm infants (Review)

2004 • 7 citations

Deleted Work

1955 • 0 citations