Back to search

Inability to Immunize Patients with Metastatic Melanoma Using Plasmid DNA Encoding the gp100 Melanoma-Melanocyte Antigen

Data up to Jan 2025

Published2003
Citations109
References49

Total Citations Per Year

Abstract

References (49)

Direct Gene Transfer into Mouse Muscle in Vivo

1990 • 3,985 citations

Cancer immunotherapy: moving beyond current vaccines

2004 • 2,932 citations

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

1993 • 2,330 citations

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

1998 • 1,826 citations

Genetic immunization is a simple method for eliciting an immune response

1992 • 1,505 citations

Progress in human tumour immunology and immunotherapy

2001 • 1,327 citations

DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations.

1993 • 1,122 citations

Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization

1996 • 1,078 citations

Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection.

1994 • 921 citations

Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans.

1993 • 888 citations

Induction of Antigen-Specific Cytotoxic T Lymphocytes in Humans by a Malaria DNA Vaccine

1998 • 844 citations

Long-term persistence of plasmid DNA and foreign gone expression in mouse muscle

1992 • 743 citations

Gene inoculation generates immune responses against human immunodeficiency virus type 1.

1993 • 655 citations

First Human Trial of a DNA-Based Vaccine for Treatment of Human Immunodeficiency Virus Type 1 Infection: Safety and Host Response

1998 • 637 citations

Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues.

1996 • 566 citations

Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression.

1995 • 552 citations

Direct Gene Transfer into Skeletal MuscleIn Vivo: Factors Affecting Efficiency of Transfer and Stability of Expression

1993 • 380 citations

In vivo engineering of a cellular immune response by co-administration of IL-12 expression vector with a DNA immunogen

1997 • 347 citations

Bovine herpesvirus 1: immune responses in mice and cattle injected with plasmid DNA

1993 • 344 citations

Plasmid DNA Is Superior to Viral Vectors for Direct Gene Transfer into Adult Mouse Skeletal Muscle

1993 • 314 citations

Immunizing Patients With Metastatic Melanoma Using Recombinant Adenoviruses Encoding MART-1 or gp100 Melanoma Antigens

1998 • 306 citations

Effect of intron A from human cytomegalovirus (Towne) immediate-early gene on heterologous expression in mammalian cells

1991 • 297 citations

Enhancement of cellular immunity in melanoma patients immunized with a peptide from MART-1/Melan A.

1997 • 286 citations

In vivo engineering of a cellular immune response by coadministration of IL-12 expression vector with a DNA immunogen.

1997 • 286 citations

Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways

2002 • 272 citations

Potential DNA Vaccine Integration into Host Cell Genome

1995 • 268 citations

Cytokine enhancement of DNA immunization leads to effective treatment of established pulmonary metastases.

1996 • 245 citations

Encapsulated plasmid DNA treatment for human papillomavirus 16-associated anal dysplasia: a Phase I study of ZYC101.

2002 • 225 citations

Immunization against epitopes in the human melanoma antigen gp100 following patient immunization with synthetic peptides.

1996 • 215 citations

A phase I trial of DNA vaccination with a plasmid expressing prostate-specific antigen in patients with hormone-refractory prostate cancer

2004 • 191 citations

Immunogenicity of a plasmid DNA vaccine encoding chimeric idiotype in patients with B-cell lymphoma.

2002 • 180 citations

Protection against leishmaniasis by injection of DNA encoding a major surface glycoprotein, gp63, of L. major.

1995 • 171 citations

Safety and immunogenicity of a DNA vaccine encoding carcinoembryonic antigen and hepatitis B surface antigen in colorectal carcinoma patients.

2002 • 140 citations

Principles and Practice of the Biologic Therapy of Cancer

2000 • 134 citations

A carcinoembryonic antigen polynucleotide vaccine has in vivo antitumor activity.

1995 • 117 citations

Enhancement of immune responses by DNA vaccination through targeted gene delivery using mannosylated cationic liposome formulations following intravenous administration in mice

2004 • 107 citations

Protection against malaria by immunization with a Plasmodium yoelii circumsporozoite protein nucleic acid vaccine

1994 • 94 citations

Recombinant fowlpox viruses encoding the anchor-modified gp100 melanoma antigen can generate antitumor immune responses in patients with metastatic melanoma.

2003 • 90 citations

Enhancement of Cellular Immune Response in HIV-1 Seropositive Individuals: A DNA-Based Trial

1999 • 87 citations

Intranasal administration of human immunodeficiency virus type‐1 (HIV‐1) DNA vaccine with interleukin‐2 expression plasmid enhances cell‐mediated immunity against HIV‐1

1998 • 75 citations

Protection against a lethal challenge with SV40-transformed cells by the direct injection of DNA-encoding SV40 large tumor antigen.

1996 • 59 citations

Development of effective immunotherapy for the treatment of patients with cancer

2004 • 54 citations

Immunization by Direct DNA Inoculation Induces Rejection of Tumor Cell Challenge

1995 • 51 citations

Phase I/II study of immunotherapy with T-cell peptide epitopes in patients with stage IV melanoma

2004 • 50 citations

Colorectal cancer vaccines: Principles, results, and perspectives

2004 • 31 citations

Development of Immunotherapy for Pancreatic Cancer

2004 • 20 citations

Recent advances in tumour antigen‐specific therapy: In vivo veritas

2004 • 15 citations

Aplicação da célula de comutação ZVS-PWM no conversor CC-CC ponte completa

1998 • 3 citations

Development of immunotherapy for cancer: Lessons from melanoma research

2004 • 1 citations

Cited By (0)

Loading...
Inability to Immunize Patients with Metastatic Melanoma Using Plasmid DNA Encoding the… (2003) – Human Gene Therapy | Metascience Observatory Explorer