Efficiency of the adaptive response of Escherichia coli to alkylating agents

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

1969 • 949 citations

A new pathway for DNA repair in Escherichia coli

1977 • 705 citations

Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N′-nitro-N-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation

1970 • 500 citations

Persistence of O 6-Ethylguanine in Rat-Brain DNA: Correlation with Nervous System-Specific Carcinogenesis by Ethylnitrosourea

1974 • 495 citations

Adaptive response to alkylating agents involves alteration in situ of O6-methylguanine residues in DNA

1979 • 260 citations

An adaptive response of E. coli to low levels of alkylating agent: Comparison with previously characterised DNA repair pathways

1977 • 225 citations

Studies on radiation-sensitive mutants of E. coli

1968 • 200 citations

Repair of O6-methylguanine in adapted Escherichia coli.

1978 • 180 citations

Isolation and characterization of Escherichia coli K-12 mutants unable to induce the adaptive response to simple alkylating agents

1979 • 160 citations

Quantitation of the adaptive response to alkylating agents

1979 • 145 citations

The mutability toward ultarviolet light of recombination-deficient strains of Escherichia coli

1969 • 144 citations

THE FREQUENCY DISTRIBUTION OF SPONTANEOUS BACTERIOPHAGE MUTANTS AS EVIDENCE FOR THE EXPONENTIAL RATE OF PHAGE REPRODUCTION

1951 • 124 citations

Increased excision of O6-methylguanine from rat liver DNA after chronic administration of dimethylnitrosamine.

1979 • 101 citations