Separation and Partial Characterization of Three Distinct Intracellular GLUT4 Compartments in Rat Adipocytes

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Metabolism of Isolated Fat Cells

1964 • 4,431 citations

ENDOCYTOSIS AND MOLECULAR SORTING

1996 • 1,537 citations

Endocytosis

1997 • 1,263 citations

Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat.

1991 • 874 citations

Insulin-regulatable tissues express a unique insulin-sensitive glucose transport protein

1988 • 661 citations

Signaling Mechanisms That Regulate Glucose Transport

1999 • 525 citations

Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes.

1995 • 522 citations

Molecular Basis of Insulin-stimulated GLUT4 Vesicle Trafficking

1999 • 417 citations

The 100-kDa Neurotensin Receptor Is gp95/Sortilin, A Non-G-Protein-coupled Receptor

1998 • 382 citations

Moving GLUT4: The Biogenesis and Trafficking of GLUT4 Storage Vesicles

1997 • 301 citations

Members of the VAMP family of synaptic vesicle proteins are components of glucose transporter-containing vesicles from rat adipocytes.

1992 • 275 citations

Comparison of GLUT4 and GLUT1 subcellular trafficking in basal and insulin-stimulated 3T3-L1 cells.

1993 • 252 citations

Insulin Increases the Association of Akt-2 with Glut4-containing Vesicles

1998 • 242 citations

Syntaxin 4, VAMP2, and/or VAMP3/Cellubrevin Are Functional Target Membrane and Vesicle SNAP Receptors for Insulin-Stimulated GLUT4 Translocation in Adipocytes

1997 • 236 citations

Effects of insulin on steady state kinetics of GLUT4 subcellular distribution in rat adipocytes. Evidence of constitutive GLUT4 recycling.

1992 • 225 citations

Inhibition of Clathrin-Mediated Endocytosis Selectively Attenuates Specific Insulin Receptor Signal Transduction Pathways

1998 • 215 citations

The glucose transporter (GLUT-4) and vesicle-associated membrane protein-2 (VAMP-2) are segregated from recycling endosomes in insulin-sensitive cells.

1996 • 211 citations

Disassembly of the actin network inhibits insulin-dependent stimulation of glucose transport and prevents recruitment of glucose transporters to the plasma membrane.

1994 • 204 citations

Synip

1999 • 183 citations

gp160, a tissue-specific marker for insulin-activated glucose transport.

1994 • 167 citations

Immunoelectron microscopic demonstration of insulin-stimulated translocation of glucose transporters to the plasma membrane of isolated rat adipocytes and masking of the carboxyl-terminal epitope of intracellular GLUT4.

1991 • 162 citations

Insulin and okadaic acid induce Rab4 redistribution in adipocytes.

1993 • 154 citations

Insulin action on the internalization of the GLUT4 glucose transporter in isolated rat adipocytes

1993 • 149 citations

Compartment ablation analysis of the insulin-responsive glucose transporter (GLUT4) in 3T3-L1 adipocytes

1996 • 147 citations

Targeting signals and subunit interactions in coated vesicle adaptor complexes.

1995 • 145 citations

Cloning and expression of gamma-adaptin, a component of clathrin-coated vesicles associated with the Golgi apparatus.

1990 • 138 citations

GLUT4Gene Regulation and Manipulation

1999 • 133 citations

Insulin-mediated Targeting of Phosphatidylinositol 3-Kinase to GLUT4-containing Vesicles

1996 • 129 citations

Akt-2 Binds to Glut4-containing Vesicles and Phosphorylates Their Component Proteins in Response to Insulin

1999 • 128 citations

The glucose transporter GluT4 and secretory carrier membrane proteins (SCAMPs) colocalize in rat adipocytes and partially segregate during insulin stimulation.

1993 • 121 citations

Preservation of structural and functional polarity in isolated epithelial cells

1996 • 118 citations

Characterization of a major protein in GLUT4 vesicles. Concentration in the vesicles and insulin-stimulated translocation to the plasma membrane.

1994 • 118 citations

Cellubrevin Is a Resident Protein of Insulin-sensitive GLUT4 Glucose Transporter Vesicles in 3T3-L1 Adipocytes

1995 • 115 citations

Sortilin Is a Major Protein Component of Glut4-containing Vesicles

1997 • 114 citations

Syndet, an Adipocyte Target SNARE Involved in the Insulin-induced Translocation of GLUT4 to the Cell Surface

1998 • 112 citations

Localization of transferrin receptors and insulin-like growth factor II receptors in vesicles from 3T3-L1 adipocytes that contain intracellular glucose transporters.

1989 • 96 citations

Endocytosis of the Glucose Transporter GLUT4 Is Mediated by the GTPase Dynamin

1998 • 94 citations

Metabolism of Isolated Fat Cells

1967 • 86 citations

A distinct class of intracellular storage vesicles, identified by expression of the glucose transporter GLUT4.

1994 • 85 citations

Phosphatidylinositol 4-kinase is a component of glucose transporter (GLUT 4)-containing vesicles

1991 • 83 citations

Perturbation of Dynamin II with an Amphiphysin SH3 Domain Increases GLUT4 Glucose Transporters at the Plasma Membrane in 3T3-L1 Adipocytes

1998 • 76 citations

Immunological analysis of GLUT4-enriched vesicles. Identification of novel proteins regulated by insulin and diabetes

1993 • 72 citations

Multiple endosomal recycling pathways in rat adipose cells

1998 • 65 citations

Insulin-sensitive association of GLUT-4 with endocytic clathrin-coated vesicles revealed with the use of brefeldin A.

1994 • 64 citations

Association of Acyl-CoA Synthetase-1 with GLUT4-containing Vesicles

1998 • 58 citations

Purification of insulin-dependent exocytic vesicles containing the glucose transporter.

1987 • 58 citations

The Insulin-like Growth Factor II/Mannose 6-Phosphate Receptor Utilizes the Same Membrane Compartments as GLUT4 for Insulin-dependent Trafficking to and from the Rat Adipocyte Cell Surface

1996 • 57 citations

Insulin stimulates the acute release of adipsin from 3T3-L1 adipocytes

1989 • 55 citations

Vp165 and GLUT4 share similar vesicle pools along their trafficking pathways in rat adipose cells

1997 • 54 citations

Differential intracellular localizations of GDP dissociation inhibitor isoforms. Insulin-dependent redistribution of GDP dissociation inhibitor-2 in 3T3-L1 adipocytes.

1994 • 54 citations

Insulin and phorbol esters affect the maximum velocity rather than the half-saturation constant of 3-O-methylglucose transport in rat adipocytes.

1986 • 50 citations

Phenylarsine oxide causes an insulin-dependent, GLUT4-specific degradation in rat adipocytes.

1991 • 31 citations

A Myosin-Derived Peptide C109 Binds to GLUT4-Vesicles and Inhibits the Insulin-Induced Glucose Transport Stimulation and GLUT4 Recruitment in Rat Adipocytes

1997 • 9 citations