Perturbation of Dynamin II with an Amphiphysin SH3 Domain Increases GLUT4 Glucose Transporters at the Plasma Membrane in 3T3-L1 Adipocytes

Induction of mutant dynamin specifically blocks endocytic coated vesicle formation.

1994 • 1,206 citations

Interaction of Tyrosine-Based Sorting Signals with Clathrin-Associated Proteins

1995 • 955 citations

Molecular cloning and characterization of an insulin-regulatable glucose transporter

1989 • 919 citations

Insulin Action and the Insulin Signaling Network*

1995 • 823 citations

Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals

1995 • 760 citations

Mutations in human dynamin block an intermediate stage in coated vesicle formation

1993 • 702 citations

Reconstitution of the transport of protein between successive compartments of the golgi measured by the coupled incorporation of N-acetylglucosamine

1984 • 689 citations

Identification of a novel gene encoding an insulin-responsive glucose transporter protein

1989 • 601 citations

The GTPase dynamin binds to and is activated by a subset of SH3 domains

1993 • 557 citations

Synaptic Vesicle Endocytosis Impaired by Disruption of Dynamin-SH3 Domain Interactions

1997 • 479 citations

Effects of mutant rat dynamin on endocytosis

1993 • 453 citations

The synaptic vesicle cycle: a single vesicle budding step involving clathrin and dynamin.

1996 • 412 citations

A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals.

1996 • 408 citations

Clathrin-independent pinocytosis is induced in cells overexpressing a temperature-sensitive mutant of dynamin.

1995 • 400 citations

BIN1 is a novel MYC–interacting protein with features of a tumour suppressor

1996 • 358 citations

Protein sorting by tyrosine-based signals: adapting to the Ys and wherefores

1997 • 329 citations

Insulin-regulated Glucose Uptake in Rat Adipocytes Is Mediated by Two Transporter Isoforms Present in at Least Two Vesicle Populations

1989 • 321 citations

Translocation of the glucose transporter (GLUT4) to the cell surface in permeabilized 3T3-L1 adipocytes: effects of ATP insulin, and GTP gamma S and localization of GLUT4 to clathrin lattices

1992 • 307 citations

Use of bismannose photolabel to elucidate insulin-regulated GLUT4 subcellular trafficking kinetics in rat adipose cells. Evidence that exocytosis is a critical site of hormone action.

1993 • 297 citations

Structural Determinants of Interaction of Tyrosine-based Sorting Signals with the Adaptor Medium Chains

1996 • 294 citations

The dynamins: Redundant or distinct functions for an expanding family of related GTPases?

1997 • 286 citations

Dynamin GTPase regulated by protein kinase C phosphorylation in nerve terminals

1993 • 272 citations

Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes.

1996 • 272 citations

Glucose transporter expression in brain. cDNA sequence of mouse GLUT3, the brain facilitative glucose transporter isoform, and identification of sites of expression by in situ hybridization.

1992 • 265 citations

The SH3 Domain of Amphiphysin Binds the Proline-rich Domain of Dynamin at a Single Site That Defines a New SH3 Binding Consensus Sequence

1997 • 256 citations

Comparison of GLUT4 and GLUT1 subcellular trafficking in basal and insulin-stimulated 3T3-L1 cells.

1993 • 252 citations

Amphiphysin II (SH3P9; BIN1), a Member of the Amphiphysin/Rvs Family, Is Concentrated in the Cortical Cytomatrix of Axon Initial Segments and Nodes of Ranvier in Brain and around T Tubules in Skeletal Muscle

1997 • 243 citations

Insulin stimulates cellular iron uptake and causes the redistribution of intracellular transferrin receptors to the plasma membrane.

1986 • 236 citations

Molecular Mechanisms in Synaptic Vesicle Endocytosis and Recycling

1996 • 229 citations

Effects of insulin on steady state kinetics of GLUT4 subcellular distribution in rat adipocytes. Evidence of constitutive GLUT4 recycling.

1992 • 225 citations

Cloning of ligand targets: Systematic isolation of SH3 domain-containing proteins

1996 • 224 citations

Characterization of Munc-18c and Syntaxin-4 in 3T3-L1 Adipocytes

1997 • 213 citations

Insulin elicits a redistribution of transferrin receptors in 3T3-L1 adipocytes through an increase in the rate constant for receptor externalization.

1987 • 190 citations

Identification of dynamin 2, an isoform ubiquitously expressed in rat tissues.

1994 • 185 citations

Inhibition of receptor-mediated endocytosis by the amphiphysin SH3 domain

1997 • 179 citations

Identification and Characterization of a Nerve Terminal-enriched Amphiphysin Isoform

1997 • 176 citations

Differential expression and regulation of multiple dynamins.

1994 • 172 citations

Potential mechanism of the stimulatory action of insulin on insulin-like growth factor II binding to the isolated rat adipose cell. Apparent redistribution of receptors cycling between a large intracellular pool and the plasma membrane.

1984 • 169 citations

Dynamin binds to SH3 domains of phospholipase C gamma and GRB-2.

1994 • 151 citations

Insulin action on the internalization of the GLUT4 glucose transporter in isolated rat adipocytes

1993 • 149 citations

Autoimmunity in Stiff‐Man Syndrome with breast cancer is targeted to the C‐terminal region of human amphiphysin, a protein similar to the yeast proteins, Rvs167 and Rvs161

1994 • 144 citations

Syntaxin 4 in 3T3-L1 adipocytes: regulation by insulin and participation in insulin-dependent glucose transport.

1996 • 135 citations

Association of Ash/Grb-2 with dynamin through the Src homology 3 domain.

1994 • 125 citations

Preservation of structural and functional polarity in isolated epithelial cells

1996 • 118 citations

GLUT-4 NH2 terminus contains a phenylalanine-based targeting motif that regulates intracellular sequestration.

1993 • 118 citations

Cellubrevin Is a Resident Protein of Insulin-sensitive GLUT4 Glucose Transporter Vesicles in 3T3-L1 Adipocytes

1995 • 115 citations

Association of a dynamin-like protein with the Golgi apparatus in mammalian cells.

1996 • 115 citations

Role of the Basic, Proline-rich Region of Dynamin in Src Homology 3 Domain Binding and Endocytosis

1997 • 114 citations

Distinct signals in the GLUT4 glucose transporter for internalization and for targeting to an insulin-responsive compartment.

1995 • 111 citations

A novel member of the dynamin family of GTP-binding proteins is expressed specifically in the testis

1993 • 104 citations

A double leucine within the GLUT4 glucose transporter COOH-terminal domain functions as an endocytosis signal.

1994 • 99 citations

Molecular Actions of Insulin on Glucose Transport

1995 • 98 citations

Three Dynamin‐Encoding Genes Are Differentially Expressed in Developing Rat Brain

1996 • 92 citations

Insulin-sensitive targeting of the GLUT4 glucose transporter in L6 myoblasts is conferred by its COOH-terminal cytoplasmic tail.

1995 • 87 citations

A New Member of the Amphiphysin Family Connecting Endocytosis and Signal Transduction Pathways

1997 • 83 citations

Growth factor-induced binding of dynamin to signal transduction proteins involves sorting to distinct and separate proline-rich dynamin sequences.

1994 • 81 citations

The amino terminus of GLUT4 functions as an internalization motif but not an intracellular retention signal when substituted for the transferrin receptor cytoplasmic domain

1994 • 80 citations

Molecular regulation of GLUT-4 targeting in 3T3-L1 adipocytes.

1995 • 79 citations

Insulin stimulation of GLUT-4 translocation: a model for regulated recycling

1994 • 78 citations

Dynamin and Endocytosis*

1995 • 76 citations

Two steps of insulin receptor internalization depend on different domains of the beta-subunit [published erratum appears in J Cell Biol 1993 Nov;123(4):1047]

1993 • 67 citations

Mechanism of insulin action on membrane protein recycling: a selective decrease in the phosphorylation state of insulin-like growth factor II receptors in the cell surface membrane.

1985 • 66 citations

Insulin-sensitive association of GLUT-4 with endocytic clathrin-coated vesicles revealed with the use of brefeldin A.

1994 • 64 citations

cDNA Cloning of a Novel Amphiphysin Isoform and Tissue-Specific Expression of Its Multiple Splice Variants

1997 • 63 citations

The Carboxyl Terminus of GLUT4 Contains a Serine-Leucine-Leucine Sequence That Functions as a Potent Internalization Motif in Chinese Hamster Ovary Cells

1996 • 57 citations

Dynamin II Binds to theTrans-Golgi Network

1996 • 53 citations

Glucose transporter recycling in rat adipose cells. Effects of potassium depletion.

1993 • 35 citations

The Bin1 Gene Localizes to Human Chromosome 2q14 by PCR Analysis of Somatic Cell Hybrids and Fluorescencein SituHybridization

1996 • 27 citations

Trafficking, targeting and translocation of the insulin-responsive glucose transporter, GLUT4, in adipocytes

1996 • 12 citations