Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene

Translating the Histone Code

2001 • 9,488 citations

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

1996 • 5,667 citations

The fundamental role of epigenetic events in cancer

2002 • 5,532 citations

Epigenetic Reprogramming in Mammalian Development

2001 • 2,978 citations

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

2001 • 2,768 citations

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

2001 • 2,746 citations

Regulation of Heterochromatic Silencing and Histone H3 Lysine-9 Methylation by RNAi

2002 • 2,040 citations

Chromatin modification and epigenetic reprogramming in mammalian development

2002 • 1,870 citations

Role of Histone H3 Lysine 9 Methylation in Epigenetic Control of Heterochromatin Assembly

2001 • 1,685 citations

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

2002 • 1,231 citations

The many faces of histone lysine methylation

2002 • 819 citations

Transitions in Distinct Histone H3 Methylation Patterns at the Heterochromatin Domain Boundaries

2001 • 746 citations

X-CHROMOSOME INACTIVATION IN MAMMALS

1997 • 524 citations

Methylation of Histone H3 at Lys-9 Is an Early Mark on the X Chromosome during X Inactivation

2001 • 504 citations

Reduced genomic 5-methylcytosine content in human colonic neoplasia.

1988 • 491 citations

Dependence of Heterochromatic Histone H3 Methylation Patterns on the Arabidopsis Gene DDM1

2002 • 434 citations

Securin Is Required for Chromosomal Stability in Human Cells

2001 • 351 citations

Quantitative reversed-phase high performance liquid chromatographic determination of major and modified deoxyribonucleosides in DNA

1980 • 328 citations

Hypermethylation can selectively silence individual p16ink4A alleles in neoplasia.

1998 • 260 citations

X-Inactivation and Histone H4 Acetylation in Embryonic Stem Cells

1996 • 244 citations

Variations in DNA methylation during mouse cell differentiation in vivo and in vitro.

1984 • 187 citations

X-chromosome inactivation

1999 • 179 citations

Histone H3 Lysine 9 Methylation Occurs Rapidly at the Onset of Random X Chromosome Inactivation

2002 • 174 citations

Methylation Talk Between Histones and DNA

2001 • 152 citations

X-chromosome inactivation: molecular mechanisms and genetic consequences

1994 • 141 citations

Histone modification and replacement in chromatin activation: Figure 1.

2002 • 130 citations

Molecular biology - Methylation talk between histones and DNA

2001 • 106 citations