Actin and Phosphoinositide Binding by the ActA Protein of the Bacterial Pathogen Listeria monocytogenes

Calculation of protein extinction coefficients from amino acid sequence data

1989 • 5,198 citations

Peptide Antibiotics and Their Role in Innate Immunity

1995 • 1,602 citations

Combining evolutionary information and neural networks to predict protein secondary structure

1994 • 1,471 citations

The interaction of Arp2/3 complex with actin: Nucleation, high affinity pointed end capping, and formation of branching networks of filaments

1998 • 1,388 citations

The Interaction between N-WASP and the Arp2/3 Complex Links Cdc42-Dependent Signals to Actin Assembly

1999 • 1,332 citations

A Self-Consistent Method for the Analysis of Protein Secondary Structure from Circular Dichroism

1993 • 1,032 citations

L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein

1992 • 790 citations

Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex

1999 • 771 citations

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate

1994 • 749 citations

Actin polymerization is induced by Arp 2/3 protein complex at the surface of Listeria monocytogenes

1997 • 598 citations

Structure and Functions of Channel-Forming Peptides: Magainins, Cecropins, Melittin and Alamethicin

1997 • 590 citations

How profilin promotes actin filament assembly in the presence of thymosin β4

1993 • 532 citations

PHOSPHOINOSITIDE LIPIDS AS SIGNALING MOLECULES: Common Themes for Signal Transduction, Cytoskeletal Regulation, and Membrane Trafficking

1998 • 515 citations

Interaction of Human Arp2/3 Complex and the Listeria monocytogenes ActA Protein in Actin Filament Nucleation

1998 • 500 citations

Current protocols in protein science

1996 • 473 citations

Automated assembly of protein blocks for database searching

1991 • 465 citations

A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family

1997 • 414 citations

A novel bacterial virulence gene in Listeria monocytogenes required for host cell microfilament interaction with homology to the proline-rich region of vinculin.

1992 • 411 citations

Role of Proteins of the Ena/VASP Family in Actin-based Motility of Listeria monocytogenes

1999 • 356 citations

Structure and Assembly Properties of the Intermediate Filament Protein Vimentin: The Role of its Head, Rod and Tail Domains

1996 • 340 citations

A Role for Phosphoinositide 3-Kinase in Bacterial Invasion

1996 • 331 citations

Motility of ActA protein-coated microspheres driven by actin polymerization

1999 • 315 citations

Interactions of Listeria monocytogenes with mammalian cells during entry and actin-based movement: bacterial factors, cellular ligands and signaling

1998 • 302 citations

Involvement of profilin in the actin-based motility of L. monocytogenes in cells and in cell-free extracts

1994 • 282 citations

The synthesis and cellular roles of phosphatidylinositol 4,5-bisphosphate

1998 • 267 citations

The Wiskott–Aldrich syndrome protein directs actin-based motility by stimulating actin nucleation with the Arp2/3 complex

1999 • 263 citations

Host cell heparan sulfate proteoglycans mediate attachment and entry of Listeria monocytogenes, and the listerial surface protein ActA is involved in heparan sulfate receptor recognition

1997 • 210 citations

The tandem repeat domain in the Listeria monocytogenes ActA protein controls the rate of actin-based motility, the percentage of moving bacteria, and the localization of vasodilator-stimulated phosphoprotein and profilin.

1996 • 208 citations

Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction

1998 • 206 citations

The unrelated surface proteins ActA of Listeria monocytogenes and lcsA of Shigella flexneri are sufficient to confer actin‐based motility on Listeria innocua and Escherichia coli respectively

1995 • 176 citations

The amino‐terminal part of ActA is critical for the actin‐based motility of Listeria monocytogenes; the central proline‐rich region acts as a stimulator

1995 • 146 citations

Actin-based movement of Listeria monocytogenes: actin assembly results from the local maintenance of uncapped filament barbed ends at the bacterium surface.

1995 • 141 citations

Lipid Products of Phosphoinositide 3-Kinase Bind Human Profilin with High Affinity

1996 • 140 citations

Identification of two regions in the N-terminal domain of ActA involved in the actin comet tail formation by Listeria monocytogenes

1997 • 135 citations

Actin filament nucleation by the bacterial pathogen, Listeria monocytogenes.

1990 • 134 citations

Asymmetric distribution of the Listeria monocytogenes ActA protein is required and sufficient to direct actin‐based motility

1995 • 131 citations

Lipid regulators of membrane traffic through the Golgi complex

1999 • 127 citations

Spatial Control of Actin Filament Assembly

1998 • 110 citations

Identification, characterization and cloning of myr 1, a mammalian myosin-I.

1993 • 107 citations

Lipid Products of Phosphoinositide 3-Kinase Interact with Rac1 GTPase and Stimulate GDP Dissociation

1998 • 103 citations

A chimeric toxin to study the role of the 21 kDa GTP binding protein rho in the control of actin microfilament assembly.

1993 • 96 citations

Targeting of Listeria monocytogenes ActA protein to the plasma membrane as a tool to dissect both actin-based cell morphogenesis and ActA function.

1995 • 79 citations

iactA of Listeria ivanovii, although distantly related to Listeria monocytogenes actA, restores actin tail formation in an L. monocytogenes actA mutant

1995 • 71 citations

Identification of cofilin, coronin, Rac and capZ in actin tails using a Listeria affinity approach

1998 • 67 citations

Actin polymerization: Where the WASP stings

1999 • 63 citations

ABM-1 and ABM-2 Homology Sequences: Consensus Docking Sites for Actin-Based Motility Defined by Oligoproline Regions in Listeria ActA Surface Protein and Human VASP

1997 • 57 citations

Structural changes in profilin accompany its binding to phosphatidylinositol 4,5‐bisphosphate

1992 • 57 citations

A method for the separation of GST fusion proteins from co-purifying GroEL

1996 • 56 citations

Spectroscopic studies of a phosphoinositide-binding peptide from gelsolin: behavior in solutions of mixed solvent and anionic micelles

1995 • 40 citations

ActA is a dimer

1997 • 36 citations

Kinetic evidence for insertion of actin monomers between the barbed ends of actin filaments and barbed end-bound insertin, a protein purified from smooth muscle

1989 • 36 citations

Actin polymerization and bacterial movement

1998 • 30 citations

Nonhomologous DNA end joining of synthetic hairpin substrates inXenopus laevisegg extracts

1994 • 23 citations

Capping of the barbed ends of actin filaments by a high-affinity profilin-actin complex

1997 • 14 citations