Intergenic Regions between Tandem gp63 Genes Influence the Differential Expression of gp63 RNAs in Leishmania chagasi Promastigotes

Iron-Responsive Elements: Regulatory RNA Sequences That Control mRNA Levels and Translation

1988 • 707 citations

Identification of an Infective Stage of Leishmania Promastigotes

1984 • 498 citations

Stable transfection of the human parasite Leishmania major delineates a 30-kilobase region sufficient for extrachromosomal replication and expression.

1990 • 450 citations

Coupling of poly(A) site selection and trans-splicing in Leishmania.

1993 • 345 citations

Genetic complementation reveals a novel regulatory role for 3? untranslated regions in growth and differentiation

1993 • 245 citations

Metacyclogenesis is a major determinant of Leishmania promastigote virulence and attenuation

1987 • 233 citations

α-Amanitin-insensitive transcription of variant surface glycoprotein genes provides further evidence for discontinuous transcription in trypanosomes

1984 • 228 citations

The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine, and oncogene mRNAs.

1991 • 222 citations

Development of a stable Leishmania expression vector and application to the study of parasite surface antigen genes.

1990 • 222 citations

Tumor suppression by RNA from the 3′ untranslated region of α-tropomyosin

1993 • 201 citations

Temporal order of RNA-processing reactions in trypanosomes: rapid trans splicing precedes polyadenylation of newly synthesized tubulin transcripts.

1993 • 189 citations

Polycistronic Transcripts in Trypanosomes and Their Accumulation During Heat Shock: Evidence for a Precursor Role in mRNA Synthesis

1988 • 174 citations

The 35-Nucleotide Spliced Leader Sequence Is Common to All Trypanosome Messenger RNA's

1986 • 164 citations

MOLECULAR DETERMINANTS OF LEISHMANIA VIRULENCE

1990 • 159 citations

The promastigote surface protease of leishmania

1987 • 154 citations

Mechanism of lethal effect of human serum upon Leishmania donovani.

1980 • 142 citations

Leishmania and Trypanosoma surface glycoproteins have a common glycophospholipid membrane anchor.

1986 • 129 citations

Three distinct RNAs for the surface protease gp63 are differentially expressed during development of Leishmania donovani chagasi promastigotes to an infectious form.

1992 • 129 citations

Growth cycle-dependent generation of complement-resistant Leishmania promastigotes.

1985 • 122 citations

Developmental modification of the lipophosphoglycan from Leishmania major promastigotes during metacyclogenesis

1990 • 120 citations

Leishmania and the macrophage: a marriage of inconvenience

1989 • 117 citations

Procyclic acidic repetitive protein (PARP) genes located in an unusually small alpha-amanitin-resistant transcription unit: PARP promoter activity assayed by transient DNA transfection of Trypanosoma brucei.

1990 • 112 citations

Hydrogen peroxide-mediated toxicity for Leishmania donovani chagasi promastigotes. Role of hydroxyl radical and protection by heat shock.

1991 • 112 citations

Apparent generation of a segmented mRNA from two separate tandem gene families inTrypanosoma cruzi

1985 • 106 citations

Requirement of a polypyrimidine tract for trans-splicing in trypanosomes: discriminating the PARP promoter from the immediately adjacent 3′ splice acceptor site.

1991 • 105 citations

Expression of the major surface glycoprotein of Leishmania donovani chagasi in virulent and attenuated promastigotes.

1989 • 91 citations

Stable DNA transfection of a wide range of trypanosomatids

1991 • 76 citations

Isolation of genes showing increased or unique expression in the infective promastigotes of Leishmania major

1990 • 71 citations

Maturation of Polycistronic Pre-mRNA in Trypanosoma brucei: Analysis of trans Splicing and Poly(A) Addition at Nascent RNA Transcripts from the hsp70 Locus

1991 • 65 citations

Sequence diversity and organization of the msp gene family encoding gp63 of Leishmania chagasi

1993 • 64 citations

The 3' untranslated region of localized maternal messages contains a conserved motif involved in mRNA localization.

1992 • 64 citations

The major concanavalin A-binding surface glycoprotein of Leishmania donovani chagasi promastigotes is involved in attachment to human macrophages.

1988 • 57 citations

Biochemical characteristics of the metacyclic forms ofLeishmania majorandL. mexicana mexicana

1989 • 55 citations

The effect of ongoing protein synthesis on the steady state levels of Gp63 RNAs in Leishmania chagasi

1993 • 52 citations

Linkage of the calmodulin and ubiquitin loci in Trypanosoma cruzi

1990 • 51 citations

Gene regulation through messenger RNA stability

1989 • 47 citations

Alternate trans Splicing in Trypanosoma equiperdum: Implications for Splice Site Selection

1988 • 43 citations

Differential response to RNAtrans-splicing signals within the phosphoglycerate kinase gene cluster inTrypanosoma brucei

1993 • 41 citations

Characterization of trypanosome protein phosphatase 1 and 2A catalytic subunits

1991 • 35 citations

Genomic and transcriptional linkage of the genes for calmodulin, EF-hand 5 protein, and ubiquitin extension protein 52 in Trypanosoma brucei.

1993 • 32 citations

Genes selectively expressed in the infectious (metacyclic) stage of Leishmania major promastigotes encode a potential basic-zipper structural motif

1992 • 27 citations