Gene gun-mediated intracutaneous vaccination with papillomavirus E7 gene delays cancer development of papillomavirus-induced skin papillomas on rabbits

Evidence for a Causal Association Between Human Papillomavirus and a Subset of Head and Neck Cancers

2000 • 3,004 citations

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

1993 • 2,360 citations

Estimates of the worldwide incidence of 25 major cancers in 1990

1999 • 2,103 citations

Escape of Human Solid Tumors from T–Cell Recognition: Molecular Mechanisms and Functional Significance

1999 • 1,168 citations

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles.

1993 • 900 citations

Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines

1987 • 760 citations

Emerging Principles for the Recognition of Peptide Antigens by MHC Class I Molecules

1992 • 730 citations

Systemic immunization with papillomavirus L1 protein completely prevents the development of viral mucosal papillomas.

1995 • 683 citations

Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein.

1986 • 665 citations

Heat Shock Protein–Peptide Complexes, Reconstituted In Vitro, Elicit Peptide-specific Cytotoxic T Lymphocyte Response and Tumor Immunity

1997 • 567 citations

Integration of human papillomavirus type 16 DNA into the human genome leads to increased stability of E6 and E7 mRNAs: implications for cervical carcinogenesis.

1995 • 529 citations

Bone Marrow–generated Dendritic Cells Pulsed with Tumor Extracts or Tumor RNA Induce Antitumor Immunity against Central Nervous System Tumors

1997 • 443 citations

Molecular Pathogenesis of Cancer of the Cervix and Its Causation by Specific Human Papillomavirus Types

1994 • 381 citations

Human papillomavirus (HPV) in head and neck cancer

1997 • 373 citations

HLA DR–DQ associations with cervical carcinoma show papillomavirus–type specificity

1994 • 329 citations

Behavior of mild cervical dysplasia during long-term follow-up

1987 • 324 citations

Human Papillomavirus Infections in Nonmelanoma Skin Cancers From Renal Transplant Recipients and Nonimmunosuppressed Patients

1996 • 304 citations

Behavior of Mild Cervical Dysplasia During Long-Term Follow-up

1986 • 296 citations

Human papillomavirus type 16 nucleoprotein E7 is a tumor rejection antigen.

1991 • 249 citations

Human papillomavirus infection and cervical intraepithelial neoplasia in women with renal allografts.

1989 • 223 citations

Infiltration of cervical cancer tissue with human papilloma virus-specific cytotoxic T-lymphocytes

1997 • 196 citations

Occasional memory cytotoxic T-cell responses of patients with human papillomavirus type 16-positive cervical lesions against a human leukocyte antigen-A *0201-restricted E7-encoded epitope.

1996 • 180 citations

Specific types of human papillomavirus found in benign proliferations and carcinomas of the skin in immunosuppressed patients.

1994 • 180 citations

Immunotherapy of a human papillomavirus (HPV) type 16 E7-expressing tumour by administration of fusion protein comprisingMycobacterium bovisbacille Calmette–Guérin (BCG) hsp65 and HPV16 E7

2000 • 176 citations

Cytotoxic T Lymphocyte Responses to E6 and E7 Proteins of Human Papillomavirus Type 16: Relationship to Cervical Intraepithelial Neoplasia

1997 • 162 citations

Immunization against human papillomavirus type 16 tumor cells with recombinant vaccinia viruses expressing E6 and E7

1991 • 160 citations

Age-dependence of human papillomavirus DNA presence in oral squamous cell carcinomas

1996 • 145 citations

Linkage of regression and malignant conversion of rabbit viral papillomas to MHC class II genes

1992 • 141 citations

Human papillomavirus in head and neck squamous cell carcinoma: are some head and neck cancers a sexually transmitted disease?

1999 • 137 citations

Prevalence of mucosotropic human papillomaviruses in squamous-cell carcinomas of the head and neck

1996 • 129 citations

The Shope Papilloma-Carcinoma Complex of Rabbits: A Model System of Neoplastic Progression and Spontaneous Regression

1981 • 110 citations

Anal Human Papillomavirus Infection among Human Immunodeficiency Virus-Seropositive and -Seronegative Men

1990 • 104 citations

Human papillomavirus-specific cytotoxic T lymphocytes in patients with cervical intraepithelial neoplasia grade III.

1997 • 101 citations

Phenotypical characterization of lymphocytes infiltrating regressing papillomas

1996 • 86 citations

Epidermodysplasia Verruciformis

1987 • 84 citations

Gene gun-mediated DNA vaccination induces antitumor immunity against human papillomavirus type 16 E7-expressing murine tumor metastases in the liver and lungs

1999 • 83 citations

Polynucleotide viral vaccines: codon optimisation and ubiquitin conjugation enhances prophylactic and therapeutic efficacy

2001 • 78 citations

Immunoprevention of cancer: is the time ripe?

2000 • 76 citations

Vaccination against human cancers (review).

2000 • 73 citations

Papovaviridae: The Papillomaviruses

1988 • 73 citations

Infiltration of cervical cancer tissue with human papilloma virus-specific cytotoxic T-lymphocytes

1997 • 71 citations

Induction of CD8 T Cells by Vaccination with Recombinant Adenovirus Expressing Human Papillomavirus Type 16 E5 Gene Reduces Tumor Growth

2000 • 71 citations

Regression of papillomas induced by cottontail rabbit papillomavirus is associated with infiltration of CD8+ cells and persistence of viral DNA after regression

1997 • 71 citations

Protection of Rabbits from Viral Challenge by Gene Gun-Based Intracutaneous Vaccination with a Combination of Cottontail Rabbit Papillomavirus E1, E2, E6, and E7 Genes

1999 • 70 citations

Vaccination against papillomavirus in cattle

1997 • 68 citations

DNA Vaccination Prevents and/or Delays Carcinoma Development of Papillomavirus-Induced Skin Papillomas on Rabbits

2000 • 64 citations

Immunization of rabbits with cottontail rabbit papillomavirus E1 and E2 genes: protective immunity induced by gene gun-mediated intracutaneous delivery but not by intramuscular injection

2000 • 64 citations

Cytokine Therapy for Cancer

2000 • 61 citations

Human papillomaviruses: General features

1997 • 61 citations

Granulocyte-Macrophage Colony-Stimulating Factor Priming plus Papillomavirus E6 DNA Vaccination: Effects on Papilloma Formation and Regression in the Cottontail Rabbit Papillomavirus-Rabbit Model

2000 • 60 citations

HLA class II DR-DQ and increased risk of cervical cancer among Senegalese women.

2001 • 57 citations

The rabbit viral skin papillomas and carcinomas: A model for the immunogenetics of HPV-associated carcinogenesis

1997 • 54 citations

Role of human papillomaviruses in cutaneous and oral manifestations of immunosuppression.

1999 • 52 citations

Changes in RNA expression pattern during the malignant progression of cottontail rabbit papillomavirus-induced tumors in rabbits

1994 • 47 citations

Natural History of Cervical Infection with Human Papillomaviruses

1994 • 45 citations

Intramuscular injection of plasmid DNA encoding cottontail rabbit papillomavirus E1, E2, E6 and E7 induces T cell-mediated but not humoral immune responses in rabbits

1999 • 38 citations

OBSERVATIONS ON THE RELATION OF THE VIRUS CAUSING RABBIT PAPILLOMAS TO THE CANCERS DERIVING THEREFROM

1936 • 36 citations

Delayed-type hypersensitivity response to the human papillomavirus type 16 E7 protein in a mouse model

1993 • 35 citations

Papillomaviruses and Carcinogenic Progression I

1987 • 30 citations

Shope rabbit papillorna-carcinoma complex a model system of HPV infections

1985 • 29 citations

Definition of rabbit class I and class II MHC gene haplotypes using molecular typing procedures

1989 • 17 citations

Immortalization of inbred rabbit keratinocytes from a Shope papilloma and tumorigenic transformation of the cells by EJ-ras

1996 • 5 citations

PP-9-1 Immunohistochemical analyses of proliferative activity in breast carcinomas with medullary features

1996 • 1 citations