Intramuscular injection of plasmid DNA encoding cottontail rabbit papillomavirus E1, E2, E6 and E7 induces T cell-mediated but not humoral immune responses in rabbits

Direct Gene Transfer into Mouse Muscle in Vivo

1990 • 3,985 citations

Genetic immunization is a simple method for eliciting an immune response

1992 • 1,505 citations

MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation

1994 • 1,448 citations

The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes

1989 • 1,345 citations

A Phagosome-to-Cytosol Pathway for Exogenous Antigens Presented on MHC Class I Molecules

1995 • 882 citations

A Mechanism for the Specific Immunogenicity of Heat Shock Protein-Chaperoned Peptides

1995 • 838 citations

Systemic immunization with papillomavirus L1 protein completely prevents the development of viral mucosal papillomas.

1995 • 683 citations

The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A

1988 • 657 citations

Immunization with viruslike particles from cottontail rabbit papillomavirus (CRPV) can protect against experimental CRPV infection

1995 • 597 citations

Gene vaccination with naked plasmid DNA: mechanism of CTL priming.

1996 • 494 citations

Molecular Pathogenesis of Cancer of the Cervix and Its Causation by Specific Human Papillomavirus Types

1994 • 381 citations

Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells.

1996 • 353 citations

The region of the HPV E7 oncoprotein homologous to adenovirus E1a and Sv40 large T antigen contains separate domains for Rb binding and casein kinase II phosphorylation.

1990 • 323 citations

Viral E1 and E2 proteins support replication of homologous and heterologous papillomaviral origins.

1992 • 302 citations

Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations.

1997 • 287 citations

Targeting antigen into the phagocytic pathway in vivo induces protective tumour immunity

1995 • 279 citations

The dominant role of bone marrow-derived cells in CTL induction following plasmid DNA immunization at different sites.

1997 • 257 citations

Specific Immune Induction Following DNA-Based Immunization Through In Vivo Transfection and Activation of Macrophages/Antigen-Presenting Cells

1998 • 223 citations

Immunization with viruslike particles induces long-term protection of rabbits against challenge with cottontail rabbit papillomavirus

1996 • 221 citations

The major human papillomavirus protein in cervical cancers is a cytoplasmic phosphoprotein

1987 • 203 citations

Protection against Papillomavirus with a Polynucleotide Vaccine

1996 • 179 citations

Transient replication of human papillomavirus DNAs

1992 • 177 citations

Vaccination with yeast-expressed cottontail rabbit papillomavirus (CRPV) virus-like particles protects rabbits from CRPV-induced papilloma formation

1995 • 167 citations

DNA Inoculation Induces Neutralizing Immune Responses Against Human Immunodeficiency Virus Type 1 in Mice and Nonhuman Primates

1993 • 166 citations

Immune responses to plasmid DNA encoding the hepatitis C virus core protein

1995 • 157 citations

DNA-based immunization with chimeric vectors for the induction of immune responses against the hepatitis C virus nucleocapsid

1995 • 154 citations

Papillomavirus DNA Replication

1994 • 148 citations

Linkage of regression and malignant conversion of rabbit viral papillomas to MHC class II genes

1992 • 141 citations

DNA immunization induces antibody and cytotoxic T cell responses to hepatitis B core antigen in H-2b mice.

1996 • 135 citations

Use of DNA Encoding Influenza Hemagglutinin as an Avian Influenza Vaccine

1993 • 125 citations

Recombinant Listeria monocytogenes vaccination eliminates papillomavirus-induced tumors and prevents papilloma formation from viral DNA

1997 • 76 citations

Intracutaneous vaccination of rabbits with the cottontail rabbit papillomavirus (CRPV) L1 gene protects against virus challenge

1997 • 65 citations

Use of Plasmid DNA for Direct Gene Transfer and Immunization

1995 • 58 citations

Intracutaneous vaccination of rabbits with the E6 gene of cottontail rabbit papillomavirus provides partial protection against virus challenge

1998 • 47 citations

Progression from papilloma to carcinoma is accompanied by changes in antibody response to papillomavirus proteins

1993 • 43 citations

DNA vaccines : a new era in vaccinology

1995 • 40 citations

Transcription of Papillomavirus Genomes

1994 • 39 citations