Hematopoietic stem cells

Establishment in culture of pluripotential cells from mouse embryos

1981 • 8,424 citations

Purification and Characterization of Mouse Hematopoietic Stem Cells

1988 • 2,856 citations

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1988 • 1,390 citations

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1988 • 1,336 citations

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

1990 • 1,208 citations

Identification of a ligand for the c-kit proto-oncogene

1990 • 970 citations

Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium

1990 • 837 citations

Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine.

1990 • 649 citations

A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations

1991 • 606 citations

Clonal and systemic analysis of long-term hematopoiesis in the mouse.

1990 • 577 citations

A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit.

1991 • 516 citations

Separation of pluripotent haematopoietic stem cells from spleen colony-forming cells

1990 • 414 citations

Clonal analysis of hematopoietic stem-cell differentiation in vivo.

1991 • 379 citations

Recombinant human stem cell factor enhances the formation of colonies by CD34+ and CD34+lin- cells, and the generation of colony-forming cell progeny from CD34+lin- cells cultured with interleukin-3, granulocyte colony-stimulating factor, or granulocyte-macrophage colony-stimulating factor

1991 • 341 citations

Competitive repopulation: a new assay for long-term stem cell functional capacity

1980 • 332 citations

Cellular and developmental properties of fetal hematopoietic stem cells

1990 • 317 citations

Use of limiting-dilution type long-term marrow cultures in frequency analysis of marrow-repopulating and spleen colony-forming hematopoietic stem cells in the mouse

1991 • 267 citations

Direct and synergistic effects of interleukin 11 on murine hemopoiesis in culture.

1991 • 234 citations

Life span of multipotential hematopoietic stem cells in vivo.

1990 • 228 citations

Mouse hematopoietic stem cells

1991 • 224 citations

The role of recombinant stem cell factor in early B cell development. Synergistic interaction with IL-7.

1991 • 222 citations

Number and continuous proliferative pattern of transplanted primitive immunohematopoietic stem cells.

1988 • 220 citations

Separation of CFU-S from primitive cells responsible for reconstitution of the bone marrow hemopoietic stem cell compartment following irradiation: evidence for a pre-CFU-S cell.

1989 • 209 citations

Effect of murine mast cell growth factor (c-kit proto-oncogene ligand) on colony formation by human marrow hematopoietic progenitor cells

1991 • 202 citations

Direct proliferative actions of stem cell factor on murine bone marrow cells in vitro: effects of combination with colony-stimulating factors.

1991 • 180 citations

Two phases of engraftment established by serial bone marrow transplantation in mice

1989 • 179 citations

Mouse hematopoietic stem cells

1991 • 178 citations

The effects on hematopoiesis of recombinant stem cell factor (ligand for c-kit) administered in vivo to mice either alone or in combination with granulocyte colony-stimulating factor

1991 • 169 citations

The effect of recombinant mast cell growth factor on purified murine hematopoietic stem cells.

1991 • 157 citations

Stem cell factor induces proliferation and differentiation of highly enriched murine hematopoietic cells.

1991 • 146 citations

Two phases of engraftment established by serial bone marrow transplantation in mice

1989 • 135 citations

Recombinant human stem cell factor, a c-kit ligand, stimulates hematopoiesis in primates

1991 • 133 citations

Synergistic interactions between interleukin-11 and interleukin-4 in support of proliferation of primitive hematopoietic progenitors of mice

1991 • 118 citations

Effects of hematopoietic growth factors on the survival of primitive stem cells in liquid suspension culture

1991 • 117 citations

Influence of murine mast cell growth factor (c-kit ligand) on colony formation by mouse marrow hematopoietic progenitor cells.

1991 • 106 citations

Culture of phenotypically defined hematopoietic stem cells and other progenitors at limiting dilution on Dexter monolayers [see comments]

1991 • 72 citations

The effect of stem cell proliferation regulators demonstrated with an in vitro assay

1988 • 72 citations

Stem cell factor in combination with granulocyte colony-stimulating factor (CSF) or granulocyte-macrophage CSF synergistically increases granulopoiesis in vivo

1991 • 67 citations

Short- and long-term repopulation of lethally irradiated mice by bone marrow stem cells enriched on the basis of light scatter and Hoechst 33342 fluorescence.

1991 • 51 citations

Leukemia inhibitory factor improves survival of retroviral vector-infected hematopoietic stem cells in vitro, allowing efficient long-term expression of vector-encoded human adenosine deaminase in vivo.

1991 • 50 citations

Fractionation of mouse bone marrow by adherence separates primitive hematopoietic stem cells from in vitro colony-forming cells and spleen colony-forming cells

1991 • 47 citations

Precursors (pre-CFCmulti) of multilineage hemopoietic colony-forming cells quantitated in vitro. Uniqueness of IL-1 requirement, partial separation from pluripotential colony-forming cells, and correlation with long term reconstituting cells in vivo.

1990 • 43 citations

Lymphoid and erythroid repopulation in B6 W-anemic mice: a new unirradiated recipient.

1991 • 37 citations

Separation of pluripotent stem cells and early B lymphocyte precursors with antibody Fall-3.

1991 • 35 citations

In vivo stem cell function of interleukin-3-induced blast cells

1991 • 16 citations

In vivo stem cell function of interleukin-3-induced blast cells

1991 • 13 citations

Temporal replacement of donor erythrocytes and leukocytes in nonanemic W44J/W44J and severely anemic W/Wv mice

1991 • 12 citations