Exclusion of CD43 from the Immunological Synapse Is Mediated by Phosphorylation-Regulated Relocation of the Cytoskeletal Adaptor Moesin

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

1999 • 3,025 citations

Three-dimensional segregation of supramolecular activation clusters in T cells

1998 • 2,316 citations

The Immunological Synapse

2001 • 987 citations

The Duration of Antigenic Stimulation Determines the Fate of Naive and Effector T Cells

1998 • 890 citations

Rho-Kinase Phosphorylates COOH-terminal Threonines of Ezrin/Radixin/Moesin (ERM) Proteins and Regulates Their Head-to-Tail Association

1998 • 849 citations

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons.

1994 • 790 citations

A Novel Adaptor Protein Orchestrates Receptor Patterning and Cytoskeletal Polarity in T-Cell Contacts

1998 • 708 citations

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling

2000 • 657 citations

A Receptor/Cytoskeletal Movement Triggered by Costimulation During T Cell Activation

1998 • 625 citations

Ezrin/Radixin/Moesin (ERM) Proteins Bind to a Positively Charged Amino Acid Cluster in the Juxta-Membrane Cytoplasmic Domain of CD44, CD43, and ICAM-2

1998 • 592 citations

Selective modulation of protein kinase C-Θ during T-cell activation

1997 • 558 citations

Cortical Actin Organization: Lessons from ERM (Ezrin/Radixin/Moesin) Proteins

1999 • 464 citations

RETRACTED: Uncoupling IL-2 Signals that Regulate T Cell Proliferation, Survival, and Fas-Mediated Activation-Induced Cell Death

1999 • 443 citations

Store-Operated Ca2+ Entry

1999 • 433 citations

Making the T Cell Receptor Go the Distance: A Topological View of T Cell Activation

1997 • 399 citations

The structure and ligand interactions of CD2: implications for T-cell function

1996 • 397 citations

ERM-Merlin and EBP50 Protein Families in Plasma Membrane Organization and Function

2000 • 375 citations

ERM proteins in cell adhesion and membrane dynamics

1999 • 364 citations

Differential Clustering of CD4 and CD3ζ During T Cell Recognition

2000 • 364 citations

Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members.

1994 • 347 citations

Synaptic pattern formation during cellular recognition

2001 • 346 citations

Association of Ezrin with Intercellular Adhesion Molecule-1 and -2 (ICAM-1 and ICAM-2)

1998 • 325 citations

Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition

2000 • 295 citations

Receptor-directed focusing of lymphokine release by helper T cells

1988 • 284 citations

The dimensions of the T lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylation.

1991 • 266 citations

T Cell Activation and the Cytoskeleton

2000 • 264 citations

Moesin Interacts with the Cytoplasmic Region of Intercellular Adhesion Molecule-3 and Is Redistributed to the Uropod of T Lymphocytes during Cell Polarization

1997 • 238 citations

Negative regulation of T-cell adhesion and activation by CD43

1995 • 236 citations

ICAM-2 redistributed by ezrin as a target for killer cells

1996 • 233 citations

Phosphorylation of Moesin by Rho-associated Kinase (Rho-kinase) Plays a Crucial Role in the Formation of Microvilli-like Structures

1998 • 229 citations

Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes

1999 • 229 citations

CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathway

2000 • 217 citations

Protein Kinase C-θ Phosphorylation of Moesin in the Actin-binding Sequence

1998 • 213 citations

Association of the Myosin-binding Subunit of Myosin Phosphatase and Moesin: Dual Regulation of Moesin Phosphorylation by Rho-associated Kinase and Myosin Phosphatase

1998 • 210 citations

Direct Involvement of Ezrin/Radixin/Moesin (ERM)-binding Membrane Proteins in the Organization of Microvilli in Collaboration with Activated ERM Proteins

1999 • 209 citations

A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation

2000 • 194 citations

CD43 Interacts With Moesin and Ezrin and Regulates Its Redistribution to the Uropods of T Lymphocytes at the Cell-Cell Contacts

1998 • 188 citations

The specific direct interaction of helper T cells and antigen-presenting B cells. II. Reorientation of the microtubule organizing center and reorganization of the membrane-associated cytoskeleton inside the bound helper T cells.

1987 • 177 citations

The serine phosphatases PP1 and PP2A associate with and activate the actin-binding protein cofilin in human T lymphocytes

2000 • 161 citations

From synapses to immunological memory: the role of sustained T cell stimulation

2000 • 153 citations

Antigen-dependent and -independent Ca2+ Responses Triggered in T Cells by Dendritic Cells Compared with B Cells

1998 • 151 citations

C-Terminal Threonine Phosphorylation Activates ERM Proteins to Link the Cell's Cortical Lipid Bilayer to the Cytoskeleton

1998 • 147 citations

Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes

2000 • 143 citations

Information transfer at the immunological synapse

2000 • 141 citations

Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott–Aldrich syndrome

1991 • 139 citations

CD43 is a murine T cell costimulatory receptor that functions independently of CD28.

1995 • 137 citations

Cutting Edge: TCR Signaling Induces Selective Exclusion of CD43 from the T Cell-Antigen-Presenting Cell Contact Site

1998 • 123 citations

Dependence of T Cell Antigen Recognition on the Dimensions of an Accessory Receptor–Ligand Complex

1999 • 123 citations

Imaging antigen recognition by naive CD4+ T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium response

1998 • 121 citations

Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its insensitivity to calpain

1999 • 119 citations

Replacement of Threonine 558, a Critical Site of Phosphorylation of Moesin in Vivo, with Aspartate Activates F-actin Binding of Moesin

1999 • 84 citations

Protein Phosphatase 2C Inactivates F-actin Binding of Human Platelet Moesin

1999 • 50 citations

Absence of CD43 Fails to Alter T Cell Development and Responsiveness

2001 • 40 citations