A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation

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1999 • 3,025 citations

Three-dimensional segregation of supramolecular activation clusters in T cells

1998 • 2,316 citations

Supported Membranes: Scientific and Practical Applications

1996 • 2,116 citations

Lymphocyte responses and cytokines

1994 • 1,860 citations

T Lymphocyte Costimulation Mediated by Reorganization of Membrane Microdomains

1999 • 964 citations

A Receptor/Cytoskeletal Movement Triggered by Costimulation During T Cell Activation

1998 • 625 citations

Supported planar membranes in studies of cell-cell recognition in the immune system

1986 • 547 citations

Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

2000 • 527 citations

Normal B lymphocyte development but impaired T cell maturation in CD45-Exon6 protein tyrosine phosphatase-deficient mice

1993 • 509 citations

Phosphoprotein Associated with Glycosphingolipid-Enriched Microdomains (Pag), a Novel Ubiquitously Expressed Transmembrane Adaptor Protein, Binds the Protein Tyrosine Kinase Csk and Is Involved in Regulation of T Cell Activation

2000 • 457 citations

Making the T Cell Receptor Go the Distance: A Topological View of T Cell Activation

1997 • 399 citations

T cell antigen receptor signal transduction

1997 • 390 citations

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation.

1996 • 382 citations

Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains.

1996 • 312 citations

Transient Confinement of a Glycosylphosphatidylinositol-Anchored Protein in the Plasma Membrane

1997 • 303 citations

Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition

2000 • 295 citations

Liprins, a Family of LAR Transmembrane Protein-tyrosine Phosphatase-interacting Proteins

1998 • 288 citations

Interspecies spleen-myeloma hybrid producing monoclonal antibodies against mouse lymphocyte surface glycoprotein, T200.

1978 • 282 citations

Visualizing the dynamics of T cell activation: Intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels

1998 • 275 citations

Positive and negative regulation of Src-family membrane kinases by CD45

1999 • 184 citations

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2015 • 179 citations

Atomic structure of an alpha beta T cell receptor (TCR) heterodimer in complex with an anti-TCR Fab fragment derived from a mitogenic antibody

1998 • 174 citations

CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion

1997 • 170 citations

Specific interaction of the CD45 protein-tyrosine phosphatase with tyrosine-phosphorylated CD3 zeta chain.

1994 • 163 citations

Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes

2000 • 143 citations

Cutting Edge: The CD45 Tyrosine Phosphatase Is an Inhibitor of Lck Activity in Thymocytes

1999 • 135 citations

Topology of the CD2–CD48 cell-adhesion molecule complex: implications for antigen recognition by T cells

1995 • 124 citations

Cutting Edge: TCR Signaling Induces Selective Exclusion of CD43 from the T Cell-Antigen-Presenting Cell Contact Site

1998 • 123 citations

The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation.

1994 • 106 citations

Rapid deletion of rearranged T cell antigen receptor (TCR) Vα-Jα segment by secondary rearrangement in the thymus: Role of continuous rearrangement of TCR α chain gene and positive selection in the T cell repertoire formation

1998 • 104 citations

Science in Japan: Competition on Campus

1996 • 78 citations

Expression of the p56^lck Y505F Mutation in CD45-Deficient Mice Rescues Thymocyte Development

1999 • 76 citations

Biochemical Association of CD45 with the T Cell Receptor Complex

1999 • 70 citations

Signal Transduction by the Lymphocyte-Specific Tyrosine Protein Kinase p56lck

1996 • 64 citations

Regulation of Integrin-Mediated T Cell Adhesion by the Transmembrane Protein Tyrosine Phosphatase CD45

1999 • 63 citations

Chapter 11 Interpretation of Fluorescence Correlation Spectroscopy and Photobleaching Recovery in Terms of Molecular Interactions

1989 • 51 citations

Mapping the fodrin binding domain in CD45, a leukocyte membrane-associated tyrosine phosphatase.

1994 • 47 citations

The regulation of B- and T-lymphocyte activation by the transmembrane protein tyrosine phosphatase CD45

1994 • 41 citations

Receptor protein-tyrosine phosphatase signalling in development.

1999 • 38 citations

Definition of Amino Acids Sufficient for Plasma Membrane Association of CD45 and CD45-Associated Protein

1997 • 17 citations

Activation of CD45-deficient T cell clones by lectin mitogens but not anti-Thy-1

1994 • 17 citations

Reconstitution of Interactions between Protein-tyrosine Phosphatase CD45 and Tyrosine-protein Kinase p56 in Nonlymphoid Cells

1997 • 16 citations