Protein Kinase C-θ Phosphorylation of Moesin in the Actin-binding Sequence

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor

1993 • 1,376 citations

Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

1993 • 1,360 citations

Lipid Asymmetry in Membranes

1979 • 1,245 citations

Protein kinase C - a question of specificity

1994 • 958 citations

Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.

1995 • 684 citations

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway.

1996 • 601 citations

Selective modulation of protein kinase C-Θ during T-cell activation

1997 • 558 citations

Coordination of Three Signaling Enzymes by AKAP79, a Mammalian Scaffold Protein

1996 • 557 citations

Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3.

1994 • 553 citations

PKCu is a novel, atypical member of the protein kinase C family.

1994 • 519 citations

How do protein kinases recognize their substrates?

1996 • 470 citations

Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site.

1995 • 422 citations

Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family.

1994 • 395 citations

Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor.

1989 • 385 citations

ERM (ezrin/radixin/moesin) family: from cytoskeleton to signal transduction

1997 • 363 citations

Molecular cloning and characterization of PKC iota, an atypical isoform of protein kinase C derived from insulin-secreting cells.

1993 • 352 citations

Sequence and domain structure of talin

1990 • 314 citations

Ezrin is a cyclic AMP-dependent protein kinase anchoring protein

1997 • 309 citations

Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells.

1993 • 306 citations

cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1.

1989 • 253 citations

Protein Kinase C-θ Isoenzyme Selective Stimulation of the Transcription Factor Complex AP-1 in T Lymphocytes

1996 • 251 citations

Moesin: a member of the protein 4.1-talin-ezrin family of proteins.

1991 • 250 citations

A new member of the third class in the protein kinase C family, PKC lambda, expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells.

1994 • 236 citations

Expression, purification, and characterization of protein kinase C-epsilon.

1990 • 231 citations

More on target with protein phosphorylation: conferring specificity by location.

1996 • 225 citations

A Ki-1 (CD30)-positive human cell line (Karpas 299) established from a high-grade non-Hodgkin's lymphoma, showing a 2;5 translocation and rearrangement of the T-cell receptor beta-chain gene

1988 • 214 citations

Cytoskeletal proteins inside human immunodeficiency virus type 1 virions

1996 • 212 citations

Phosphorylation of Threonine 558 in the Carboxyl-terminal Actin-binding Domain of Moesin by Thrombin Activation of Human Platelets

1995 • 205 citations

Moesin, ezrin, and p205 are actin-binding proteins associated with neutrophil plasma membranes.

1995 • 169 citations

Direct Interaction between Protein Kinase Cθ (PKCθ) and 14-3-3τ in T Cells: 14-3-3 Overexpression Results in Inhibition of PKCθ Translocation and Function†

1996 • 158 citations

Phosphorylation reverses the membrane association of peptides that correspond to the basic domains of MARCKS and neuromodulin

1994 • 152 citations

A heparin-binding protein involved in inhibition of smooth-muscle cell proliferation

1988 • 127 citations

Biochemical Characterization of Ezrin-Actin Interaction

1996 • 125 citations

The human keratinocyte two‐dimensional gel protein database (update 1992): Towards an integrated approach to the study of cell proliferation, differentiation and skin diseases

1992 • 125 citations

Indirect association of ezrin with F-actin: isoform specificity and calcium sensitivity.

1995 • 120 citations

The HIV Nef Protein Associates with Protein Kinase C Theta

1996 • 100 citations

A manual sequencing method for identification of phosphorylated amino acids in phosphopeptides

1991 • 87 citations

Deamidation and isoaspartate formation during in vitro aging of recombinant tissue plasminogen activator.

1994 • 83 citations

Expression and Biochemical Characterization of Human Protein Kinase C‐θ

1994 • 83 citations

Phosphorylation of the gamma chain of the high affinity receptor for immunoglobulin E by receptor-associated protein kinase C-delta.

1994 • 64 citations

Molecular Cloning, cDNA Sequence, and Chromosomal Assignment of the Human Radixin Gene and Two Dispersed Pseudogenes

1993 • 51 citations

Unique expression pattern of protein kinase C‐θ: high mRNA levels in normal mouse testes and in T‐lymphocytic cells and neoplasms

1993 • 46 citations

Phosphorylation of558T of Moesin Detected by Site-Specific Antibodies in RAW264.7 Macrophages

1996 • 44 citations

Zonal electrophoresis and isoelectric focusing of proteins and virus particles in density gradients of small volume

1974 • 32 citations

Moesin, a new cytoskeletal protein and constituent of filopodia: Its role in cellular functions

1992 • 30 citations

Partial purification of a type η protein kinase C from murine brain: separation from other protein kinase C isoenzymes and characterization

1994 • 27 citations

Manganese-phospholipid-stimulated protein kinase activity of human leukemic cells.

1985 • 25 citations

[18] Expression, separation, and assay of protein kinase C subspecies

1991 • 25 citations

[21] Estimation of phosphorylation stoichiometry by separation of phosphorylated isoforms

1991 • 25 citations

Mapping of the human protein kinase C-θ (PRKCQ) gene locus to the short arm of chromosome 10 (10p15) by FISH

1995 • 17 citations

Binding of Myristoylated Alanine-Rich Protein Kinase C Substrate to Phosphoinositides Attenuates the Phosphorylation by Protein Kinase C

1996 • 15 citations

A distinctive phospholipid-stimulated protein kinase of normal and malignant murine hemopoietic cells.

1987 • 13 citations

Purification and assay of a phosphatidylglycerol-stimulated protein kinase from murine leukemic cells and its perturbation in response to IL-3 and PMA treatment.

1988 • 11 citations

The 47-kD fragment of talin is a substrate for protein kinase P

1993 • 7 citations