Functional Analysis of the Amino-terminal 8-kDa Domain of DNA Polymerase β as Revealed by Site-directed Mutagenesis
Data up to Jan 2025
Total Citations Per Year
Abstract
References (31)
Molecular Cloning: A Laboratory Manual
2001 • 133,517 citations
Molecular cloning: A laboratory manual
1990 • 85,659 citations
[19] Rapid and efficient site-specific mutagenesis without phenotypic selection
1987 • 5,413 citations
Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
1991 • 5,267 citations
Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1)
1997 • 779 citations
Heat-induced deamination of cytosine residues in deoxyribonucleic acid
1974 • 725 citations
Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP.
1994 • 694 citations
Excision of Deoxyribose Phosphate Residues by DNA Polymerase β During DNA Repair
1995 • 670 citations
Crystal Structures of Human DNA Polymerase β Complexed with Gapped and Nicked DNA: Evidence for an Induced Fit Mechanism,
1997 • 601 citations
Structures of Ternary Complexes of Rat DNA Polymerase β, a DNA Template-Primer, and ddCTP
1994 • 587 citations
The base excision repair pathway
1995 • 536 citations
Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure.
1995 • 485 citations
The enzymology of apurinic/apyrimidinic endonucleases
1990 • 378 citations
DNA Polymerase β Conducts the Gap-filling Step in Uracil-initiated Base Excision Repair in a Bovine Testis Nuclear Extract
1995 • 317 citations
Generation of single-nucleotide repair patches following excision of uracil residues from DNA.
1992 • 290 citations
Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA Glycosylase
1995 • 259 citations
Crystal Structures of Human DNA Polymerase β Complexed with DNA: Implications for Catalytic Mechanism, Processivity, and Fidelity,
1996 • 255 citations
Reconstitution of the DNA base excision—repair pathway
1994 • 243 citations
Evidence for an Imino Intermediate in the DNA Polymerase β Deoxyribose Phosphate Excision Reaction
1996 • 165 citations
Substrate Binding by Human Apurinic/Apyrimidinic Endonuclease Indicates a Briggs-Haldane Mechanism
1997 • 154 citations
Studies of gapped DNA substrate binding by mammalian DNA polymerase beta. Dependence on 5'-phosphate group.
1994 • 132 citations
Mechanism of action of a mammalian DNA repair endonuclease
1986 • 120 citations
Identification and properties of the catalytic domain of mammalian DNA polymerase .beta.
1990 • 87 citations
DNA deoxyribophosphodiesterase.
1988 • 76 citations
Enzymic release of 5'-terminal deoxyribose phosphate residues from damaged DNA in human cells
1991 • 64 citations
Identification of residues in the single-stranded DNA-binding site of the 8-kDa domain of rat DNA polymerase beta by UV cross-linking.
1993 • 50 citations
DNA Polymerase β in Abasic Site Repair: A Structurally Conserved Helix−Hairpin−Helix Motif in Lesion Detection by Base Excision Repair Enzymes
1997 • 39 citations
Three-Dimensional Solution Structure of the N-Terminal Domain of DNA Polymerase β and Mapping of the ssDNA Interaction Interface,
1996 • 37 citations
Active-site modification of mammalian DNA polymerase .beta. with pyridoxal 5'-phosphate: mechanism of inhibition and identification of lysine 71 in the deoxynucleoside triphosphate binding pocket
1989 • 34 citations
Assignments of 1H, 15N, and 13C Resonances for the Backbone and Side Chains of the N-Terminal Domain of DNA Polymerase .beta.. Determination of the Secondary Structure and Tertiary Contacts
1994 • 22 citations
Insights into the mechanism of the β-elimination catalyzed by the N-terminal domain of DNA polymerase β
1997 • 17 citations