Reconstitution of the DNA base excision—repair pathway

Instability and decay of the primary structure of DNA

1993 • 5,370 citations

REPAIR OF OXIDATIVE DAMAGE TO DNA: Enzymology and Biology

1994 • 1,435 citations

Mutagenic deamination of cytosine residues in DNA

1980 • 761 citations

Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP.

1994 • 694 citations

Structures of Ternary Complexes of Rat DNA Polymerase β, a DNA Template-Primer, and ddCTP

1994 • 587 citations

Rate of chain breakage at apurinic sites in double-stranded deoxyribonucleic acid

1972 • 586 citations

DNA N-glycosidases: properties of uracil-DNA glycosidase from Escherichia coli.

1977 • 513 citations

Endonuclease IV (nfo) mutant of Escherichia coli

1986 • 397 citations

Structure-Specific Endonucleolytic Cleavage of Nucleic Acids by Eubacterial DNA Polymerases

1993 • 369 citations

Generation of single-nucleotide repair patches following excision of uracil residues from DNA.

1992 • 290 citations

Identification and purification of a single-stranded-DNA-specific exonuclease encoded by the recJ gene of Escherichia coli.

1989 • 275 citations

Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: an alternative pathway of base excision DNA repair.

1994 • 268 citations

New class of enzymes acting on damaged DNA

1976 • 259 citations

Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells.

1990 • 253 citations

Short gap-filling synthesis by DNA polymerase beta is processive

1993 • 228 citations

Method for the isolation of Escherichia coli mutants with enhanced recombination between chromosomal duplications

1977 • 192 citations

Homogeneous Escherichia coli endonuclease IV. Characterization of an enzyme that recognizes oxidative damage in DNA.

1988 • 183 citations

Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme.

1989 • 183 citations

It was a very good year for DNA repair

1994 • 181 citations

Apurinic/apyrimidinic endonucleases in repair of pyrimidine dimers and other lesions in DNA.

1980 • 163 citations

Excision of 5'-terminal deoxyribose phosphate from damaged DNA is catalyzed by the Fpg protein of Escherichia coli.

1992 • 147 citations

DNA repair synthesis during base excision repair in vitro is catalyzed by DNA polymerase epsilon and is influenced by DNA polymerases alpha and delta in Saccharomyces cerevisiae.

1993 • 141 citations

Mammalian DNA polymerase beta can substitute for DNA polymerase I during DNA replication in Escherichia coli.

1992 • 99 citations

Release of 5′-terminal deoxyribose-phosphate residues from incised abasic sites in DNA by theEscherichia coliRecJ protein

1994 • 98 citations

Damage repertoire of the Escherichia coli UvrABC nuclease complex includes abasic sites, base-, damage analogues, and lesions containing adjacent 5' or 3' nicks

1990 • 89 citations

Possible roles of β-elimination and δ-elimination reactions in the repair of DNA containing AP (apurinic/apyrimidinic) sites in mammalian cells

1988 • 88 citations

In vitro mutagenesis and functional expression inEscherichia coliof a cDNA encoding the catalytic domain of human DNA ligase I

1991 • 88 citations

Transient generation of displaced single-stranded DNA during nick translation

1982 • 80 citations

Genetic recombination in Escherichia coli: Holliday junctions made by RecA protein are resolved by fractionated cell-free extracts.

1990 • 68 citations

Enzymic release of 5'-terminal deoxyribose phosphate residues from damaged DNA in human cells

1991 • 64 citations

Characterization of the action of Escherichia coli DNA polymerase I at incisions produced by repair endodeoxyribonucleases.

1982 • 59 citations

Repair of a synthetic abasic site in DNA in a Xenopus laevis oocyte extract.

1989 • 58 citations

In Vitro Repair of Apurinic Sites in DNA

1974 • 50 citations

Repair of a synthetic abasic site involves concerted reactions of DNA synthesis followed by excision and ligation.

1991 • 49 citations

Action of Escherichia coli and human 5′ → 3′ exonuclease functions at incised apurinic/apyrimidinic sites in DNA

1992 • 15 citations

Deleted Work

1955 • 0 citations