Enzymic release of 5'-terminal deoxyribose phosphate residues from damaged DNA in human cells

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region

1983 • 618 citations

Rate of chain breakage at apurinic sites in double-stranded deoxyribonucleic acid

1972 • 586 citations

DNA N-glycosidases: properties of uracil-DNA glycosidase from Escherichia coli.

1977 • 513 citations

Complementation of the xeroderma pigmentosum DNA repair defect in cell-free extracts

1988 • 448 citations

Two forms of repair in the DNA of human cells damaged by chemical carcinogens and mutagens.

1974 • 439 citations

Endonuclease IV (nfo) mutant of Escherichia coli

1986 • 397 citations

The enzymology of apurinic/apyrimidinic endonucleases

1990 • 378 citations

Complete enzymatic synthesis of DNA containing the SV40 origin of replication.

1988 • 297 citations

ENZYMATIC SYNTHESIS AND BREAKDOWN OF DESOXYRIBOSE PHOSPHATE

1952 • 255 citations

Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells.

1990 • 253 citations

Escherichia coli endonuclease III is not an endonuclease but a β-elimination catalyst

1987 • 247 citations

Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs.

1989 • 225 citations

A new endonuclease from Escherichia coli acting at apurinic sites in DNA.

1977 • 225 citations

Involvement of helicase II (uvrD gene product) and DNA polymerase I in excision mediated by the uvrABC protein complex.

1985 • 222 citations

Purification and characterization of Escherichia coli endonuclease III from the cloned nth gene

1989 • 212 citations

Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme.

1989 • 183 citations

A new mechanism for repairing oxidative damage to DNA: (A)BC excinuclease removes AP sites and thymine glycols from DNA

1989 • 177 citations

Stereochemical studies of the .beta.-elimination reactions at aldehydic abasic sites in DNA: endonuclease III from Escherichia coli, sodium hydroxide, and Lys-Trp-Lys

1991 • 160 citations

Discontinuous DNA synthesis by purified mammalian proteins.

1990 • 135 citations

Repair of intrinsic DNA lesions

1990 • 126 citations

Properties of Deoxyribonuclease III from Mammalian Tissues

1969 • 115 citations

Mammalian DNA ligases. Catalytic domain and size of DNA ligase I.

1990 • 109 citations

Excision repair and DNA synthesis with a combination of HeLa DNA polymerase beta and DNase V.

1983 • 107 citations

Isolation and structure of a cDNA expressing a mammalian 3-methyladenine-DNA glycosylase.

1990 • 104 citations

DEOXYRIBONUCLEASE IV: A NEW EXONUCLEASE FROM MAMMALIAN TISSUES

1969 • 100 citations

Phosphodiesterases Involved in DNA Repair

1987 • 95 citations

Properties of the Main Endonuclease Specific for Apurinic Sites of Escherichia coli (Endonuclease VI)

1978 • 94 citations

Damage repertoire of the Escherichia coli UvrABC nuclease complex includes abasic sites, base-, damage analogues, and lesions containing adjacent 5' or 3' nicks

1990 • 89 citations

Analysis of class II (hydrolytic) and class I (β-lyase) apurinic/apyrimidinic endonucleases with a synthetic DNA substrate

1990 • 87 citations

Characterization of the action of Escherichia coli DNA polymerase I at incisions produced by repair endodeoxyribonucleases.

1982 • 59 citations

Repair of a synthetic abasic site in DNA in a Xenopus laevis oocyte extract.

1989 • 58 citations

Properties of overexpressed phage T5 D15 exonuclease. Similarities with Escherichia coli DNA polymerase I 5‘-3‘ exonuclease.

1990 • 53 citations

Excision of Pyrimidine Dimers from Ultraviolet‐Irradiated DNA by Exonucleases from Mammalian Cells

1971 • 52 citations

Presence of two different desoxyribonucleodepolymerases in veal kidney

1953 • 52 citations

IN VIVO EXCISION OF PYRIMIDINE DIMERS IS MEDIATED BY A DNA N‐GLYCOSYLASE IN MICROCOCCUS LUTEUS BUT NOT IN HUMAN FIBROBLASTS

1982 • 49 citations

Initiation of adenovirus DNA replication. I. Mechanism of action of a host protein required for replication of adenovirus DNA templates devoid of the terminal protein.

1988 • 43 citations

The multiple activities of Escherichia coli endonuclease IV and the extreme lability of 5′-terminal base-free deoxyribose 5-phosphates

1989 • 43 citations

Human placental apurinic/apyrimidinic endonuclease. Mechanism of action.

1982 • 37 citations

Repair of depurinated DNA in vitro by enzymes purified from human lymphoblasts.

1978 • 36 citations

Protein-primed replication of plasmids containing the terminus of the adenovirus genome. II. Purification and characterization of a host protein required for the replication of DNA templates devoid of the terminal protein.

1984 • 33 citations

The alkaline degradation of deoxyribonucleic acid derivatives

1968 • 30 citations

Fate of Virus DNA in the Abortive Infection of Human Lymphoid Cell Lines by Epstein-Barr Virus

1972 • 30 citations

Base excision repair of DNA in γ-irradiated human cells

1987 • 20 citations

The Action Pattern of Mammalian Deoxyribonuclease IV

1971 • 19 citations

9-Amino-ellipticine inhibits the apurinic site-dependent base excision-repair pathway

1990 • 16 citations

The use of thioglycolate to distinguish between 3' AP (apurinic/apyrimidinic) endonucleases and AP lyases

1989 • 15 citations

Deoxyribonuclease IV from rat liver chromatin and the excision of apurinic sites from depurinated DNA

1985 • 12 citations

Enhanced Deoxyribonuclease Activity in Human Transformed Cells and in Bloom's Syndrome Cells

1989 • 10 citations

Excision of apurinic and/or apyrimidinic sites from DNA by nucleolytical enzymes from rat brain

1988 • 9 citations

The use of thioglycollate to demonstrate DNA AP (apurinic/apyrimidinic-site) lyase activities. Biological consequences of thiol addition to the 5′ product of a β-elimination reaction at an AP site in DNA

1991 • 3 citations