Chromatin Signatures in Multipotent Human Hematopoietic Stem Cells Indicate the Fate of Bivalent Genes during Differentiation
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References (46)
High-Resolution Profiling of Histone Methylations in the Human Genome
2007 • 6,479 citations
A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
2006 • 5,132 citations
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
2007 • 3,994 citations
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
2007 • 3,216 citations
Genome-scale DNA methylation maps of pluripotent and differentiated cells
2008 • 2,432 citations
Combinatorial patterns of histone acetylations and methylations in the human genome
2008 • 2,214 citations
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
2007 • 2,094 citations
Hox genes in vertebrate development
1994 • 2,057 citations
Position-independent, high-level expression of the human β-globin gene in transgenic mice
1987 • 1,955 citations
A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells
2007 • 1,882 citations
AC133, a Novel Marker for Human Hematopoietic Stem and Progenitor Cells
1997 • 1,755 citations
"Stemness": Transcriptional Profiling of Embryonic and Adult Stem Cells
2002 • 1,721 citations
A Stem Cell Molecular Signature
2002 • 1,553 citations
Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse
2005 • 1,497 citations
Chromatin signatures of pluripotent cell lines
2006 • 1,288 citations
Targeted Recruitment of Set1 Histone Methylase by Elongating Pol II Provides a Localized Mark and Memory of Recent Transcriptional Activity
2003 • 1,096 citations
Lineage-Specific Polycomb Targets and De Novo DNA Methylation Define Restriction and Potential of Neuronal Progenitors
2008 • 864 citations
The Biology of Hematopoietic Stem Cells
1995 • 775 citations
Multilineage gene expression precedes commitment in the hemopoietic system.
1997 • 757 citations
Whole-Genome Analysis of Histone H3 Lysine 4 and Lysine 27 Methylation in Human Embryonic Stem Cells
2007 • 682 citations
Genetic and Epigenetic Regulators of Pluripotency
2007 • 646 citations
REGULATION OF TH2 DIFFERENTIATION ANDIl4LOCUS ACCESSIBILITY
2006 • 625 citations
Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription
2004 • 617 citations
Transcription factor GATA-3 is required for development of the T-cell lineage
1996 • 614 citations
Whole-Genome Mapping of Histone H3 Lys4 and 27 Trimethylations Reveals Distinct Genomic Compartments in Human Embryonic Stem Cells
2007 • 585 citations
Correlation Between Histone Lysine Methylation and Developmental Changes at the Chicken β-Globin Locus
2001 • 582 citations
Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells
2004 • 555 citations
The genomic landscape of histone modifications in human T cells
2006 • 478 citations
Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping
2005 • 445 citations
Dynamic chromatin modifications characterise the first cell cycle in mouse embryos
2005 • 388 citations
Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR
2006 • 361 citations
Molecular Signatures of Proliferation and Quiescence in Hematopoietic Stem Cells
2004 • 351 citations
Hematopoietic Fingerprints: An Expression Database of Stem Cells and Their Progeny
2007 • 303 citations
Role of Erythroid Kruppel-like Factor in Human γ- to β-Globin Gene Switching
1995 • 212 citations
Arrest in Primitive Erythroid Cell Development Caused by Promoter-specific Disruption of the GATA-1 Gene
1997 • 173 citations
Differential dynamics of histone H3 methylation at positions K4 and K9 in the mouse zygote
2004 • 162 citations
Differential H3K4 Methylation Identifies Developmentally Poised Hematopoietic Genes
2008 • 155 citations
Regulation of the myeloperoxidase enhancer binding proteins Pu1, C-EBP alpha, -beta, and -delta during granulocyte-lineage specification.
1996 • 139 citations
Genome-wide prediction of conserved and nonconserved enhancers by histone acetylation patterns
2006 • 130 citations
In Vitro Mass Production of Human Erythroid Cells from the Blood of Normal Donors and of Thalassemic Patients
2002 • 126 citations
Ex Vivo-Generated CD36 + Erythroid Progenitors Are Highly Permissive to Human Parvovirus B19 Replication
2007 • 99 citations
The biology of hematopoietic stem cells
2003 • 95 citations
Chapter 5 Three‐Dimensional Organization of Gene Expression in Erythroid Cells
2008 • 84 citations
B-cell development fails in the absence of the Pbx1 proto-oncogene
2007 • 69 citations
Evidence for Diversity in Transcriptional Profiles of Single Hematopoietic Stem Cells
2006 • 50 citations
Successful transplantation of haploidentically mismatched peripheral blood stem cells using CD133+-purified stem cells
2005 • 30 citations