Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

The language of covalent histone modifications

2000 • 8,260 citations

NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins

2006 • 4,425 citations

The ENCODE (ENCyclopedia Of DNA Elements) Project

2004 • 2,327 citations

NCBI Reference Sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins

2004 • 1,523 citations

Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse

2005 • 1,497 citations

Genome-wide Map of Nucleosome Acetylation and Methylation in Yeast

2005 • 1,418 citations

Genome-wide analysis of mammalian promoter architecture and evolution

2006 • 1,351 citations

The RNA Polymerase II Core Promoter

2003 • 1,092 citations

A high-resolution map of active promoters in the human genome

2005 • 922 citations

A Unified Theory of Gene Expression

2002 • 896 citations

Going the Distance: A Current View of Enhancer Action

1998 • 820 citations

Orchestrated response: a symphony of transcription factors for gene control

2000 • 763 citations

The key to development: interpreting the histone code?

2005 • 729 citations

Molecular and Functional Identification of Sodium Ion-dependent, High Affinity Human Carnitine Transporter OCTN2

1998 • 694 citations

GENCODE: producing a reference annotation for ENCODE

2006 • 616 citations

Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter

1999 • 540 citations

Single-Nucleosome Mapping of Histone Modifications in S. cerevisiae

2005 • 497 citations

Looping versus linking: toward a model for long-distance gene activation

1999 • 465 citations

Locus control regions

2002 • 459 citations

Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping

2005 • 445 citations

Spatial and Temporal Recruitment of Androgen Receptor and Its Coactivators Involves Chromosomal Looping and Polymerase Tracking

2005 • 434 citations

Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300

1997 • 428 citations

cDNA Sequence, Transport Function, and Genomic Organization of Human OCTN2, a New Member of the Organic Cation Transporter Family

1998 • 336 citations

Histone modifications: signalling receptors and potential elements of a heritable epigenetic code

2006 • 314 citations

Histone modifications defining active genes persist after transcriptional and mitotic inactivation

2004 • 263 citations

Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expression

2006 • 261 citations

Chromatin Unfolds

1996 • 253 citations

Carnitine Deficiency Disorders in Children

2004 • 223 citations

DNase-chip: a high-resolution method to identify DNase I hypersensitive sites using tiled microarrays

2006 • 221 citations

Dynamics of Enhancer-Promoter Communication during Differentiation-Induced Gene Activation

2002 • 221 citations

Mutations in the organic cation/carnitine transporter OCTN2 in primary carnitine deficiency

1999 • 195 citations

Genome-Wide Analysis of Protein-DNA Interactions

2006 • 174 citations

The transcriptional regulatory code of eukaryotic cells – insights from genome-wide analysis of chromatin organization and transcription factor binding

2006 • 118 citations

Molecular Cloning and Characterization of High-Affinity Carnitine Transporter from Rat Intestine

1998 • 102 citations

Molecular cloning and characterization of two novel transport proteins from rat kidney

1998 • 101 citations

Evidence for Linkage of Human Primary Systemic Carnitine Deficiency with D5S436: A Novel Gene Locus on Chromosome 5q

1998 • 54 citations