Whole-Genome Mapping of Histone H3 Lys4 and 27 Trimethylations Reveals Distinct Genomic Compartments in Human Embryonic Stem Cells

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

2005 • 44,461 citations

Translating the Histone Code

2001 • 9,488 citations

High-Resolution Profiling of Histone Methylations in the Human Genome

2007 • 6,479 citations

A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells

2006 • 5,132 citations

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

2007 • 3,994 citations

A gene atlas of the mouse and human protein-encoding transcriptomes

2004 • 3,443 citations

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

2007 • 3,216 citations

Polycomb complexes repress developmental regulators in murine embryonic stem cells

2006 • 2,473 citations

The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

2006 • 2,414 citations

Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells

2006 • 2,241 citations

Active genes are tri-methylated at K4 of histone H3

2002 • 2,064 citations

The Mammalian Epigenome

2007 • 1,977 citations

The diverse functions of histone lysine methylation

2005 • 1,966 citations

Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse

2005 • 1,497 citations

Chromatin signatures of pluripotent cell lines

2006 • 1,288 citations

Embryo-Derived Stem Cells: Of Mice and Men

2001 • 1,274 citations

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

2006 • 1,244 citations

Role of Histone H3 Lysine 27 Methylation in X Inactivation

2003 • 1,175 citations

A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome

2006 • 1,137 citations

Targeted Recruitment of Set1 Histone Methylase by Elongating Pol II Provides a Localized Mark and Memory of Recent Transcriptional Activity

2003 • 1,096 citations

Epigenetic Regulation of Cellular Memory by the Polycomb and Trithorax Group Proteins

2004 • 1,049 citations

A high-resolution map of active promoters in the human genome

2005 • 922 citations

Histone methylation in transcriptional control

2002 • 887 citations

SUZ12 Is Required for Both the Histone Methyltransferase Activity and the Silencing Function of the EED-EZH2 Complex

2004 • 779 citations

Histone H3 lysine 4 methylation patterns in higher eukaryotic genes

2003 • 772 citations

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

1990 • 692 citations

Establishment of Histone H3 Methylation on the Inactive X Chromosome Requires Transient Recruitment of Eed-Enx1 Polycomb Group Complexes

2003 • 646 citations

Genetic and Epigenetic Regulators of Pluripotency

2007 • 646 citations

Genome-wide analysis of Polycomb targets in Drosophila melanogaster

2006 • 591 citations

Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin

2001 • 495 citations

Molecular signature of human embryonic stem cells and its comparison with the mouse

2003 • 485 citations

Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27

2004 • 485 citations

The genomic landscape of histone modifications in human T cells

2006 • 478 citations

Reprogramming of genome function through epigenetic inheritance

2001 • 459 citations

Derivation of Multipotent Mesenchymal Precursors from Human Embryonic Stem Cells

2005 • 446 citations

Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster

2006 • 373 citations

Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes

2001 • 369 citations

Suz12 binds to silenced regions of the genome in a cell-type-specific manner

2006 • 316 citations

Large-scale human promoter mapping using CpG islands

2000 • 302 citations

Recent advances in X-chromosome inactivation

2004 • 288 citations

Mass Spectrometric Characterization of the Affinity-Purified Human 26S Proteasome Complex

2007 • 260 citations

Gene identification signature (GIS) analysis for transcriptome characterization and genome annotation

2005 • 243 citations

Chromosomal Distribution of PcG Proteins during Drosophila Development

2006 • 242 citations

Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus

2002 • 199 citations

Iroquois genes: genomic organization and function in vertebrate neural development

2002 • 170 citations

Multiplex sequencing of paired-end ditags (MS-PET): a strategy for the ultra-high-throughput analysis of transcriptomes and genomes

2006 • 129 citations

The Leading Edge of Stem Cell Therapeutics

2006 • 126 citations

X‐Inactivation Status Varies in Human Embryonic Stem Cell Lines

2005 • 122 citations

The Proteasome Restricts Permissive Transcription at Tissue-Specific Gene Loci in Embryonic Stem Cells

2006 • 114 citations

Dlx homeobox gene control of mammalian limb and craniofacial development

2006 • 95 citations

Immortalized feeders for the scale-up of human embryonic stem cells in feeder and feeder-free conditions

2005 • 81 citations