Sex-related Differences in the Influence of Morphine on Ventilatory Control in Humans

A formula to estimate the approximate surface area if height and weight be known

1916 • 4,502 citations

Gender variations in clinical pain experience

1996 • 1,525 citations

Influence of Age and Gender on the Pharmacokinetics and Pharmacodynamics of Remifentanil

1997 • 1,160 citations

Gender differences in the responses to noxious stimuli

1995 • 475 citations

Kappa–opioids produce significantly greater analgesia in women than in men

1996 • 461 citations

Diminished Ventilatory Response to Hypoxia and Hypercapnia after Morphine in Normal Man

1975 • 345 citations

Gender-related differences in the antinociceptive properties of morphine.

1996 • 260 citations

Expression of c‐fos in the rat brainstem after exposure to hypoxia and to normoxic and hyperoxic hypercapnia

1997 • 254 citations

Roles of gender, gonadectomy and estrous phase in the analgesic effects of intracerebroventricular morphine in rats

1989 • 232 citations

Central neural mechanisms of progesterone action: application to the respiratory system

1992 • 228 citations

Sexual Differentiation of the Human Nervous System

1994 • 182 citations

Sex-related differences in morphine's antinociceptive activity: relationship to serum and brain morphine concentrations.

1997 • 170 citations

The influence of oxygen on the ventilatory response to carbon dioxide in man.

1990 • 141 citations

Effects of sex steroids on the development of the locus coeruleus in the rat

1988 • 141 citations

Sex-related differences in the effects of morphine and stress on visceral pain

1989 • 136 citations

Interactions among aging, gender, and gonadectomy effects upon morphine antinociception in rats

1993 • 127 citations

Poor permeability of morphine 3-glucuronide and morphine 6-glucuronide through the blood-brain barrier in the rat.

1996 • 122 citations

Research on obesity*

1977 • 122 citations

Hypoxic ventilatory response during sleep in normal premenopausal women.

1982 • 121 citations

Sexually dimorphic opioid distribution in the preoptic area: manipulation by gonadal steroids

1986 • 118 citations

Increased HVR in pregnancy: relationship to hormonal and metabolic changes

1987 • 115 citations

Genetic sensitivity to hot-plate nociception in DBA/2J and C57BL/6J inbred mouse strains: possible sex-specific mediation by δ2-opioid receptors

1997 • 113 citations

Influence of testosterone on ventilation and chemosensitivity in male subjects

1985 • 103 citations

Respiratory depression following morphine and morphine-6-glucuronide in normal subjects.

1995 • 100 citations

The sexually dimorphic region of the preoptic area in rats contains denser opiate receptor binding sites in females

1984 • 96 citations

INHIBITORY ACTIONS OF METHIONINE‐ENKEPHALIN AND MORPHINE ON THE CAT CAROTID CHEMORECEPTORS

1980 • 82 citations

The effect of morphine and of meperidine (dolantin, demerol) upon the respiratory response of normal men to low concentrations of inspired carbon dioxide.

1953 • 77 citations

Sexual dimorphism of the dopamine-β-hydroxylase-immunoreactive neurons in the rat locus ceruleus

1992 • 74 citations

Stress-induced opioid analgesia and activity in deer mice: sex and population differences

1987 • 74 citations

Effects of morphine on ventilatory response to exercise

1979 • 73 citations

Intravenous morphine pharmacokinetics in pediatric patients with sickle cell disease

1995 • 72 citations

Influences of Morphine on the Ventilatory Response to Isocapnic Hypoxia

1997 • 70 citations

Influence of progesterone on arterial blood and CSF acid-base balance in women

1981 • 69 citations

Sex differences in discriminative stimulus effects of morphine in the rat.

1996 • 68 citations

Opioids and behavior: genetic aspects

1988 • 68 citations

Acute Pain and Central Nervous System Arousal Do Not Restore Impaired Hypoxic Ventilatory Response during Sevoflurane Sedation

1996 • 66 citations

Morphine-6-glucuronide: effects on ventilation in normal volunteers

1991 • 66 citations

Pharmacokinetics of Intravenous Morphine in Patients Anesthetized with Enflurane–Nitrous Oxide

1981 • 59 citations

Effect of Flumazenil on Ventilatory Drive during Sedation with Midazolam and Alfentanil

1996 • 57 citations

Ventilatory Effects of Fourth Cerebroventricular Infusions of Morphine-6− or Morphine-3-Glucuronide in the Awake Dog

1989 • 57 citations

The steady‐state and rebreathing methods compared during morphine administration in humans.

1989 • 46 citations

Influence of reduced carotid body drive during sustained hypoxia on hypoxic depression of ventilation in humans

1996 • 45 citations

Changes of ventilation and ventilatory response to hypoxia during the menstrual cycle

1984 • 36 citations

Spontaneously (genetic) hypertensive rats: Naloxone-reversible and propranolol-reversible decrease in pain sensitivity

1981 • 32 citations

EFFECT OF ANALGESICS ON RESPIRATORY RESPONSE TO CARBON DIOXIDE IN MAN

1949 • 29 citations

The Pharmacokinetics of Intradural Morphine in Major Abdominal Surgery

1988 • 20 citations

Theophylline effect upon respiration and ventilation in the dog: interaction with methadone.

1981 • 14 citations

The sensitivity to noxious heat in relation to brain and liver opioid glucuronidation in inbred strains of mice

1989 • 13 citations

Deleted Work

1955 • 0 citations