Intravenous morphine pharmacokinetics in pediatric patients with sickle cell disease

Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations

1978 • 2,054 citations

Pain in Sickle Cell Disease

1991 • 1,510 citations

Clinical Pharmacokinetics of Morphine

1991 • 280 citations

The analgesic activity of morphine‐6‐glucuronide.

1992 • 272 citations

Morphine metabolism in man

1974 • 228 citations

Respiratory Effects of Intravenous Morphine Infusions in Neonates, Infants, and Children After Cardiac Surgery

1993 • 168 citations

The Maturation of Morphine Clearance and Metabolism

1992 • 146 citations

The metabolite morphine-6-glucuronide contributes to the analgesia produced by morphine infusion in patients with pain and normal renal function

1992 • 135 citations

The Management of Pain in Sickle Cell Disease

1989 • 115 citations

Pain in Children and Adolescents with Sickle Cell Disease: A Descriptive Study

1990 • 107 citations

Intravenous Narcotic Therapy for Children With Severe Sickle Cell Pain Crisis

1986 • 101 citations

Ethnic differences in response to morphine

1993 • 98 citations

Epidural Analgesia in the Management of Severe Vaso-Occlusive Sickle Cell Crisis

1994 • 94 citations

Steady-state infusions of opioids in human. II. Concentration-effect relationships and therapeutic margins

1990 • 91 citations

Hepatic extraction of morphine is impaired in cirrhosis

1989 • 90 citations

The influence of renal function on the renal clearance of morphine and its glucuronide metabolites in intensive‐care patients.

1992 • 83 citations

Intermittent Injection vs Patient-Controlled Analgesia for Sickle Cell Crisis Pain

1991 • 80 citations

Analgesia in Children with Sickle Cell Crisis: Comparison of Intermittent Opioids Vs. Continuous Intravenous Infusion of Morphine and Placebo-Controlled Study of Oxygen Inhalation

1992 • 74 citations

Patient-controlled analgesia for sickle-cell-related pain

1993 • 67 citations

The use of patient-controlled analgesia in adolescents with sickle cell pain crisis: A preliminary report

1988 • 61 citations

Ketorolac for sickle cell vaso-occlusive crisis pain in the emergency department: lack of a narcotic-sparing effect

1992 • 49 citations

Pain measurement in hospitalized adults with sickle cell painful episodes.

1993 • 44 citations

VENTILATORY EFFECTS OF MORPHINE, PETHIDINE AND METHADONE IN CHILDREN

1993 • 38 citations

Oral analgesia for treatment of painful crisis in sickle cell anemia

1986 • 36 citations

Death from a morphine infusion during a sickle cell crisis

1993 • 34 citations

Cerebrospinal fluid and plasma pharmacokinetics of morphine infusions in pediatrie cancer patients and rhesus monkeys

1987 • 26 citations

Patient-Controlled Analgesia in Patients with Sickle Cell Vaso-Occlusive Crisis

1990 • 21 citations

Patient-controlled analgesia pain management for children with sickle cell disease.

1990 • 20 citations

Continuous papaveretum infusion for the control of pain in painful sickling crisis.

1990 • 8 citations