A monoclonal antibody to vascular endothelial–cadherin inhibits tumor angiogenesis without side effects on endothelial permeability

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1996 • 3,454 citations

E-cadherin germline mutations in familial gastric cancer

1998 • 1,629 citations

Linking Colorectal Cancer to Wnt Signaling

2000 • 1,507 citations

Targeted Deficiency or Cytosolic Truncation of the VE-cadherin Gene in Mice Impairs VEGF-Mediated Endothelial Survival and Angiogenesis

1999 • 1,291 citations

Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

1999 • 1,248 citations

Structural basis of cell-cell adhesion by cadherins

1995 • 1,173 citations

Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity

2000 • 1,159 citations

Cadherins in cancer: implications for invasion and metastasis

1993 • 939 citations

Tight junctions and the molecular basis for regulation of paracellular permeability

1995 • 825 citations

Cadherin-catenin complex: Protein interactions and their implications for cadherin function

1996 • 806 citations

Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors.

1999 • 660 citations

Vascular endothelial–cadherin is an important determinant of microvascular integrityinvivo

1999 • 659 citations

Cellular markers that distinguish the phases of hemangioma during infancy and childhood.

1994 • 651 citations

The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin).

1995 • 573 citations

Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal

1997 • 512 citations

Effects of Thalidomide and Related Metabolites in a Mouse Corneal Model of Neovascularization

1997 • 447 citations

A model of angiogenesis in the mouse cornea.

1996 • 411 citations

Endothelial adherens junctions: implications in the control of vascular permeability and angiogenesis.

1996 • 372 citations

High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein.

1998 • 357 citations

Monoclonal antibodies specific for endothelial cells of mouse blood vessels. Their application in the identification of adult and embryonic endothelium.

1994 • 315 citations

Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability

2001 • 293 citations

Cell confluence regulates tyrosine phosphorylation of adherens junction components in endothelial cells

1997 • 285 citations

Functional Properties of Human Vascular Endothelial Cadherin (7B4/Cadherin-5), an Endothelium-Specific Cadherin

1995 • 273 citations

Quantitative Evaluation of Vascular Permeability in the Gerbil Brain after Transient Ischemia Using Evans Blue Fluorescence

1988 • 271 citations

Endothelioma cells expressing the polyoma middle T oncogene induce hemangiomas by host cell recruitment

1989 • 252 citations

VE-Cadherin Regulates Endothelial Actin Activating Rac and Increasing Membrane Association of Tiam

2002 • 241 citations

Migration of monocytes across endothelium and passage through extracellular matrix involve separate molecular domains of PECAM-1.

1995 • 240 citations

Vascular Endothelial (VE)-Cadherin: Only an Intercellular Glue?

1999 • 238 citations

A General Strategy for Isolation of Endothelial Cells From Murine Tissues

1997 • 232 citations

Histamine Induces Tyrosine Phosphorylation of Endothelial Cell-to-Cell Adherens Junctions

1999 • 229 citations

Catenin-dependent and -independent Functions of Vascular Endothelial Cadherin

1995 • 220 citations

Multiple cadherin extracellular repeats mediate homophilic binding and adhesion

2001 • 219 citations

VE-Cadherin Mediates Endothelial Cell Capillary Tube Formation in Fibrin and Collagen Gels1

1998 • 216 citations

N-Cadherin Extracellular Repeat 4 Mediates Epithelial to Mesenchymal Transition and Increased Motility

2000 • 201 citations

Direct molecular force measurements of multiple adhesive interactions between cadherin ectodomains

1999 • 170 citations

Progressive growth in immunodeficient mice and host cell recruitment by mouse endothelial cells transformed by polyoma middle-sized T antigen: implications for the pathogenesis of opportunistic vascular tumors.

1994 • 168 citations

Direct Measurements of Multiple Adhesive Alignments and Unbinding Trajectories between Cadherin Extracellular Domains

2001 • 133 citations

Monoclonal antibody to vascular endothelial-cadherin is a potent inhibitor of angiogenesis, tumor growth, and metastasis.

2000 • 128 citations

Mapping the homotypic binding sites in CD31 and the role of CD31 adhesion in the formation of interendothelial cell contacts.

1995 • 110 citations

Development of Endothelial Cell Lines From Embryonic Stem Cells

2000 • 107 citations

A possible new adhesive site in the cell-adhesion molecule uvomorulin

1990 • 102 citations

Mechanism of homophilic cadherin adhesion

2000 • 87 citations

Endothelial adhesion molecules in the development of the vascular tree: the garden of forking paths

1999 • 72 citations

In vitro neutralization of vascular endothelial growth factor activation of Flk-1 by a monoclonal antibody

1995 • 59 citations

A novel mechanism of colon carcinoma cell adhesion to the endothelium triggered by beta 1 integrin chain.

1994 • 34 citations

Human endothelial cells expressing polyoma middle T induce tumors

2000 • 28 citations

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1966 • 27 citations

Rapid retroviral infection of human haemopoietic cells of different lineages: efficient transfer in fresh T cells

1998 • 27 citations