The zinc finger protein NRIF interacts with the neurotrophin receptor p75NTR and participates in programmed cell death

Genomic sequencing.

1984 • 8,343 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Apoptosis by Death Factor

1997 • 5,038 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

TGF-β signalling from cell membrane to nucleus through SMAD proteins

1997 • 3,650 citations

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

1993 • 2,370 citations

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

1993 • 1,531 citations

Simplified mammalian DNA isolation procedure

1991 • 1,508 citations

Targeted Disruption of Mouse EGF receptor: Effect of Genetic Background on Mutant Phenotype

1995 • 1,457 citations

Functions of the neurotrophins during nervous system development: What the knockouts are teaching us

1994 • 1,431 citations

NEUROTROPHINS AND SYNAPTIC PLASTICITY

1999 • 1,343 citations

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

1991 • 1,232 citations

Nucleocytoplasmic transport: signals, mechanisms and regulation

1997 • 987 citations

Intracellular Signaling Pathways Activated by Neuropathic Factors

1996 • 958 citations

Expression and structure of the human NGF receptor

1986 • 956 citations

Induction of Apoptosis by the Low-Affinity NGF Receptor

1993 • 774 citations

Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75

1996 • 768 citations

Induction of cell death by endogenous nerve growth factor through its p75 receptor

1996 • 750 citations

Tumor necrosis factor receptor-associated factors (TRAFs)—a family of adapter proteins that regulates life and death

1998 • 597 citations

Turning of nerve growth cones induced by neurotransmitters

1994 • 583 citations

Signal transduction by the neutrophin receptors

1997 • 573 citations

Neurotrophin Regulation of Cortical Dendritic Growth Requires Activity

1996 • 503 citations

The p75 Neurotrophin Receptor Mediates Neuronal Apoptosis and Is Essential for Naturally Occurring Sympathetic Neuron Death

1998 • 500 citations

Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background

1997 • 481 citations

Competitive Signaling Between TrkA and p75 Nerve Growth Factor Receptors Determines Cell Survival

1998 • 476 citations

Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain

1993 • 452 citations

Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR

1999 • 452 citations

The Ins and Outs of Notch Signaling

1997 • 386 citations

NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain

1996 • 379 citations

The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development.

1994 • 371 citations

The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

1991 • 368 citations

p75-Deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins

1993 • 359 citations

p75LNGFR regulates Trk signal transduction and NGF-induced neuronal differentiation in MAH cells

1994 • 353 citations

The Krüppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression.

1994 • 346 citations

DNA-Binding Specificity of NGFI-A and Related Zinc Finger Transcription Factors

1995 • 304 citations

NMR structure of the death domain of the p75 neurotrophin receptor

1997 • 301 citations

Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness.

1993 • 292 citations

p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF

1994 • 278 citations

Adherence to the first-AUG rule when a second AUG codon follows closely upon the first.

1995 • 254 citations

Neurotrophins Induce Sphingomyelin Hydrolysis

1995 • 245 citations

Regulation of apoptosis and cell cycle arrest by Zac1, a novel zinc finger protein expressed in the pituitary gland and the brain

1997 • 241 citations

Association of the p75 Neurotrophin Receptor with TRAF6

1999 • 237 citations

Nerve growth factor regulates sympathetic ganglion cell morphology and survival in the adult mouse

1990 • 227 citations

Nerve Growth Factor-Dependent Activation of NF-κB Contributes to Survival of Sympathetic Neurons

1998 • 225 citations

Signalling through the neurotrophin receptor p75NTR

1997 • 221 citations

Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord

1999 • 216 citations

The trkA Receptor Mediates Growth Cone Turning toward a Localized Source of Nerve Growth Factor

1997 • 193 citations

Molecular Cloning and Characterization of TIEG2Reveals a New Subfamily of Transforming Growth Factor-β-inducible Sp1-like Zinc Finger-encoding Genes Involved in the Regulation of Cell Growth

1998 • 190 citations

Mapping of a major genetic modifier of embryonic lethality in TGFβ1 knockout mice

1997 • 166 citations

Oligodendrocyte Apoptosis Mediated by Caspase Activation

1999 • 161 citations

Conserved biological function betweenPax-2 andPax-5 in midbrain and cerebellum development: Evidence from targeted mutations

1997 • 140 citations

Neurotrophins: the biological paradox of survival factors eliciting apoptosis

1998 • 135 citations

Krox-20 controls SCIP expression, cell cycle exit and susceptibility to apoptosis in developing myelinating Schwann cells

1999 • 130 citations

HSV-1 vector-mediated gene transfer of the human nerve growth factor receptor p75hNGFR defines high-affinity NGF binding

1993 • 127 citations

Characterization of a mouse multigene family that encodes zinc finger structures.

1988 • 127 citations

p75 Neurotrophin Receptor Expression on Adult Human Oligodendrocytes: Signaling without Cell Death in Response to NGF

1998 • 126 citations

Nerve Growth Factor Signaling through p75 Induces Apoptosis in Schwann Cells via a Bcl-2-Independent Pathway

1999 • 126 citations

Structure and developmental expression of the chicken NGF receptor

1990 • 120 citations

p75 neurotrophin receptor as a modulator of survival and death decisions

1999 • 110 citations

TrkB signalling inhibits p75-mediated apoptosis induced by nerve growth factor in embryonic proprioceptive neurons

1998 • 97 citations

Expression of the nerve growth factor-regulated NGFI-A and NGFI-B genes in the developing rat

1990 • 93 citations

Single-strand conformation polymorphism (SSCP) analysis as a tool for genetic mapping

1993 • 81 citations

Members of the zinc finger protein gene family sharing a conserved N-terminal module

1991 • 80 citations

Identification of genes differentially expressed by nerve growth factor- and neurotrophin-3-dependent sensory neurons

1997 • 80 citations

Regulation of NF-κB activity in rat dorsal root ganglia and PC12 cells by tumour necrosis factor and nerve growth factor

1995 • 78 citations

Detailed Comparative Map of Human Chromosome 19q and Related Regions of the Mouse Genome

1996 • 73 citations

Mapping genes in the mouse using single-strand conformation polymorphism analysis of recombinant inbred strains and interspecific crosses.

1992 • 72 citations

Activation of Nuclear Factor _KB in Human Neuroblastoma Cell Lines

1994 • 26 citations

Analysis of HomologousXRCC1-Linked Zinc-Finger Gene Families in Human and Mouse: Evidence for Orthologous Genes

1998 • 22 citations

The identification and characterization of KRAB-domain-containing zinc finger proteins

1992 • 21 citations