p75-Deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Purification of a new neurotrophic factor from mammalian brain.

1982 • 1,762 citations

Trophic factors and neuronal survival

1989 • 1,631 citations

BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra

1991 • 1,487 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

The trk proto-oncogene encodes a receptor for nerve growth factor

1991 • 1,396 citations

Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

1990 • 1,261 citations

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

1991 • 1,232 citations

Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family

1990 • 1,140 citations

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1991 • 1,078 citations

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF

1991 • 1,049 citations

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

1992 • 960 citations

Expression and structure of the human NGF receptor

1986 • 956 citations

Gene transfer and molecular cloning of the rat nerve growth factor receptor

1987 • 946 citations

The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3

1991 • 940 citations

Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons

1989 • 934 citations

Neurotrophin-5: A novel neurotrophic factor that activates trk and trkB

1991 • 847 citations

Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in xenopus ovary

1991 • 836 citations

trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor

1991 • 830 citations

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

1991 • 819 citations

Neurotrophin receptors: A window into neuronal differentiation

1992 • 704 citations

Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain.

1990 • 700 citations

Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease

1992 • 654 citations

The nerve growth factor family of receptors

1992 • 649 citations

Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity.

1992 • 633 citations

Nerve growth factor receptors. Characterization of two distinct classes of binding sites on chick embryo sensory ganglia cells.

1979 • 627 citations

Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor

1987 • 555 citations

Primary structure and biological activity of a novel human neurotrophic factor

1990 • 553 citations

The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3

1991 • 530 citations

Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells

1986 • 519 citations

Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor.

1992 • 458 citations

Gene Transfer and Molecular Cloning of the Human NGF Receptor

1986 • 447 citations

The house mouse. Development and normal stages from fertilization to 4 weeks of age.

1972 • 413 citations

Molecular cloning of a human gene that is a member of the nerve growth factor family.

1990 • 397 citations

Placode and neural crest-derived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor

1985 • 384 citations

Trophic regulation of nerve cell morphology and innervation in the autonomic nervous system

1988 • 342 citations

Different neurotrophins are expressed and act in a developmental sequence to promote the survival of embryonic sensory neurons

1993 • 338 citations

Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product

1992 • 336 citations

The trk B tyrosine protein kinase is a receptor for neurotrophin-4

1992 • 326 citations

Selective Induction by Nerve Growth Factor of Tyrosine Hydroxylase and Dopamine-β-Hydroxylase in the Rat Superior Cervical Ganglia

1971 • 308 citations

Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors

1991 • 296 citations

Trkl3 mediates BDNF/NT-3-dependent survival and proliferation in fibroblasts lacking the low affinity NGF receptor

1991 • 294 citations

The trk proto-oncogene rescues NGF responsiveness in mutant NGF-nonresponsive PC12 cell lines

1991 • 252 citations

The response of chick sensory neurons to brain-derived neurotrophic factor

1986 • 251 citations

Expression of Functional Nerve Growth Factor Receptors After Gene Transfer

1989 • 235 citations

Localization of the mRNA for the 5-HT2 receptor by in situ hybridization histochemistry. Correlation with the distribution of receptor sites

1990 • 234 citations

Relation of target encounter and neuronal death to nerve growth factor responsiveness in the developing mouse trigeminal ganglion

1984 • 225 citations

Neuropeptide expression in cultures of adult sensory neurons: Modulation of substance P and calcitonin gene-related peptide levels by nerve growth factor

1989 • 221 citations

Developmental change in the nerve growth factor action from induction of choline acetyltransferase to promotion of cell survival in cultured basal forebrain cholinergic neurons from postnatal rats

1988 • 208 citations

The rat trk protooncogene product exhibits properties characteristic of the slow nerve growth factor receptor.

1992 • 198 citations

Neurotrophic factors promote the maturation of developing sensory neurons before they become dependent on these factors for survival

1992 • 195 citations

Quantitative in vitro studies on the nerve growth factor (NGF) requirement of neurons

1977 • 173 citations

A new superfamily of cell surface proteins related to the nerve growth factor receptor

1991 • 172 citations

The low-affinity p75 nerve growth factor (NGF) receptor mediates NGF-induced tyrosine phosphorylation.

1991 • 153 citations

Developmental changes of nerve growth factor levels in sympathetic ganglia and their target organs

1988 • 145 citations

Binding characteristics of brain-derived neurotrophic factor to its receptors on neurons from the chick embryo

1988 • 142 citations

K. THEILER: THE HOUSE MOUSE. DEVELOPMENT AND NORMAL STAGES FROM FERTILIZATION TO 4 WEEKS OF AGE. 168 Seiten, 312 Abb. Springer Verlag, Berlin‐Heidelberg‐New York 1972, Preis: 124,— DM; 50,60 $

1975 • 137 citations

Induction by NGF of Meiotic Maturation of Xenopus Oocytes Expressing the trk Proto-Oncogene Product

1991 • 133 citations

Biochemical and anatomical effects of antibodies against nerve growth factor on developing rat sensory ganglia.

1984 • 122 citations

Quantitative in vitro studies on the nerve growth factor (NGF) requirement of neurons

1977 • 120 citations

Chimeric NGF-EGF Receptors Define Domains Responsible for Neuronal Differentiation

1991 • 116 citations

Expression of the NGF receptor gene in sensory neurons and their cutaneous targets prior to and during innervation

1990 • 113 citations

Neurotrophin-4/5 is a mammalian-specific survival factor for distinct populations of sensory neurons

1993 • 110 citations

The cranial sensory ganglia in culture: Differences in the response of placode-derived and neural crest-derived neurons to nerve growth factor

1985 • 106 citations

Molecular and cellular aspects of patterning sensory neurone connections in the vertebrate nervous system

1987 • 94 citations

Role of nerve growth factor in the development of rat sympathetic neurons in vitro. II. Developmental studies.

1977 • 88 citations

Nerve growth factor enhances neurite arborization of adult sensory neurons; a study i single-cell culture

1990 • 73 citations

Nerve Growth Factor (NGF) Induces Neuronal Differentiation in Neuroblastoma Cells Transfected with the NGF Receptor cDNA

1990 • 72 citations

NGF mRNA expression in developing cutaneous epithelium related to innervation density

1990 • 72 citations

Introduction of nerve growth factor (NGF) receptors into a medulloblastoma cell line results in expression of high- and low-affinity NGF receptors but not NGF-mediated differentiation.

1990 • 71 citations

Role of neurotrophic factors in development

1988 • 70 citations

Parasympathetic, sympathetic, and sensory interactions in the iris: nerve growth factor regulates cholinergic ciliary ganglion innervation in vivo

1985 • 69 citations

Expression of nerve growth factor receptor mRNA during early development of the chicken embryo: emphasis on cranial ganglia

1990 • 65 citations

Ectopic trkA expression mediates a NGF survival response in NGF-independent sensory neurons but not in parasympathetic neurons.

1993 • 53 citations

Nerve growth factor (NGF) induces neuronal differentiation in neuroblastoma cells transfected with the NGF receptor cDNA.

1990 • 48 citations

Fasciculation in the early mouse trigeminal nerve is not ordered in relation to the emerging pattern of whisker follicles

1986 • 42 citations

Effects of antibodies against nerve growth factor on the postnatal development of substance P-containing sensory neurons

1982 • 32 citations

Mutation of tryptophan-21 in mouse nerve growth factor (NGF) affects binding to the fast NGF receptor but not induction of neurites on PC12 cells

1991 • 26 citations

The growth rate of sensory nerve fibres in the mammalian embryo

1987 • 20 citations

Age‐related effects of nerve growth factor on the morphology of embryonic sensory neurons in vitro

1993 • 16 citations

The highs and lows of an NGF receptor

1992 • 11 citations