Specific inhibition of iNOS decreases the intestinal mucosal peroxynitrite level and improves the barrier function after thermal injury

Peroxynitrite oxidation of sulfhydryls.

1991 • 2,479 citations

Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide

1991 • 2,215 citations

Extensive Nitration of Protein Tyrosines in Human Atherosclerosis Detected by Immunohistochemistry

1994 • 1,138 citations

Evidence for nitric oxide‐mediated oxidative damage in chronic inflammation Nitrotyrosine in serum and synovial fluid from rheumatoid patients

1994 • 718 citations

Inhibition of Mitochondrial Electron Transport by Peroxynitrite

1994 • 697 citations

DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite.

1996 • 630 citations

Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury.

1994 • 599 citations

Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease

1996 • 588 citations

A STANDARD ANIMAL BURN

1968 • 533 citations

Amelioration of chronic ileitis by nitric oxide synthase inhibition.

1993 • 416 citations

Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase.

1994 • 409 citations

Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity

1995 • 274 citations

A critical role for nitric oxide in intestinal barrier function and dysfunction

1996 • 254 citations

Turning on the respiratory burst

1990 • 211 citations

Bacterial translocation from the gut: a mechanism of infection.

1987 • 177 citations

Nitric oxide in the gut.

1995 • 164 citations

Endogenous nitric oxide as a mediator of gastric mucosal vasodilatation during acid secretion

1992 • 145 citations

Bacterial Translocation from the Gut

1987 • 141 citations

Peroxynitrite Formed by Simultaneous Nitric Oxide and Superoxide Generation Causes Cyclosporin‐A‐Sensitive Mitochondrial Calcium Efflux and Depolarisation

1995 • 140 citations

Time‐dependent enhancement or inhibition of endotoxin‐induced vascular injury in rat intestine by nitric oxide synthase inhibitors

1994 • 137 citations

Role of endogenous nitric oxide in septic shock.

1993 • 131 citations

Postburn gastrointestinal vasoconstriction increases bacterial and endotoxin translocation

1993 • 124 citations

Peroxynitrite-induced cardiac myocyte injury

1996 • 111 citations

Peroxynitrite inhibition of oxygen consumption and sodium transport in alveolar type II cells

1994 • 111 citations

Bulk Prevents Bacterial Translocation Induced by the Oral Administration of Total Parenteral Nutrition Solution

1990 • 103 citations

Bacterial translocation after thermal injury

1993 • 102 citations

Inhibition of Nitric Oxide With Aminoguanidine Reduces Bacterial Translocation After Endotoxin Challenge In Vivo

1996 • 101 citations

Expression of Inducible Nitric Oxide Synthase mRNA in Rat Digestive Tissues after Endotoxin and Its Role in Intestinal Mucosal Injury

1996 • 85 citations

Induction of Nitric Oxide Synthase and Concomitant Suppression of Superoxide Dismutases in Experimental Colitis in Rats

1995 • 80 citations

Peroxynitrite inhibits sodium uptake in rat colonic membrane vesicles

1992 • 73 citations

Nitric oxide in inflammation and immunity.

1995 • 64 citations

ENDOTOXIN-INDUCED OXIDATIVE STRESS IN THE RAT SMALL INTESTINE

1996 • 46 citations

Reduction of bacterial translocation with oral fibroblast growth factor and sucralfate

1993 • 26 citations

Use of nitric oxide synthase inhibitors in animal models of sepsis.

1995 • 23 citations

NITROSYL COMPLEX FORMATION DURING ENDOTOXIN-INDUCED INJURY IN THE RAT SMALL INTESTINE

1996 • 13 citations