The Notch pathway: democracy and aristocracy in the selection of cell fate

A new member of the frizzled family from Drosophila functions as a Wingless receptor

1996 • 1,489 citations

Signalling downstream of activated mammalian Notch

1995 • 1,375 citations

Notch Signaling

1995 • 1,282 citations

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

1994 • 749 citations

The choice of cell fate in the epidermis of Drosophila

1991 • 736 citations

Control of Daughter Cell Fates during Asymmetric Division: Interaction of Numb and Notch

1996 • 656 citations

Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity.

1995 • 594 citations

Asymmetric segregation of Numb and Prospero during cell division

1995 • 489 citations

The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD

1994 • 483 citations

Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.

1996 • 481 citations

Intrinsic activity of the lin-12 and Notch intracellular domains in vivo

1993 • 466 citations

Truncated Mammalian Notch1 Activates CBF1/RBPJk-Repressed Genes by a Mechanism Resembling That of Epstein-Barr Virus EBNA2

1996 • 459 citations

Proneural clusters of achaete-scute expression and the generation of sensory organs in the Drosophila imaginal wing disc.

1991 • 444 citations

The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling.

1995 • 430 citations

Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei.

1993 • 421 citations

Numb Antagonizes Notch Signaling to Specify Sibling Neuron Cell Fates

1996 • 415 citations

Early events in insect neurogenesis

1985 • 403 citations

Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing

1995 • 392 citations

lag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans

1994 • 385 citations

Expression of an extracellular deletion of Xotch diverts cell fate in Xenopus embryos

1993 • 366 citations

The wingless signalling pathway and the patterning of the wing margin in Drosophila

1994 • 354 citations

Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila

1996 • 331 citations

Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation.

1996 • 316 citations

Masking of the CBF1/RBPJ _κ Transcriptional Repression Domain by Epstein-Barr Virus EBNA2

1995 • 296 citations

Recognition sequence of a highly conserved DNA binding protein RBP-J_x

1994 • 287 citations

The Notch signalling pathway is required for Enhancer of split bHLH protein expression during neurogenesis in the Drosophila embryo

1994 • 283 citations

Delta-Notch Signaling and Drosophila Cell Fate Choice

1994 • 268 citations

Neurogenic genes and vertebrate neurogenesis

1996 • 268 citations

Sequence of C. elegans lag-2 reveals a cell-signalling domain shared with Delta and Serrate of Drosophila

1994 • 260 citations

Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision

1994 • 254 citations

Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS

1995 • 249 citations

A Screen for Genes That Function Downstream of Ras1 During Drosophila Eye Development

1996 • 246 citations

Cell autonomy of lin-12 function in a cell fate decision in C. elegans

1989 • 241 citations

wingless expression mediates determination of peripheral nervous system elements in late stages of Drosophila wing disc development

1993 • 234 citations

lag-1, a gene required for lin-12 and glp-1 signaling in Caenorhabditis elegans, is homologous to human CBF1 and Drosophila Su(H)

1996 • 232 citations

The maternal genes apx-1 and glp-1 and establishment of dorsal-ventral polarity in the early C. elegans embryo

1994 • 227 citations

The shortest path from the surface to the nucleus: RBP‐Jκ/Su(H) transcription factor

1996 • 207 citations

Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila

1995 • 199 citations

Inhibition of the DNA-binding activity of Drosophila suppressor of hairless and of its human homolog, KBF2/RBP-J kappa, by direct protein-protein interaction with Drosophila hairless.

1994 • 160 citations

Neuroblast Specification and Formation Regulated by wingless in the Drosophila CNS

1993 • 157 citations

Nature versus nurture: Asymmetric cell divisions in Drosophila bristle development

1994 • 155 citations

Subcellular localization of Suppressor of Hairless in Drosophila sense organ cells during Notch signalling

1996 • 148 citations

Antagonistic activities of Suppressor of Hairless and Hairless control alternative cell fates in the Drosophila adult epidermis

1994 • 144 citations

Structure/function studies of lin-12/Notch proteins

1994 • 122 citations

tramtrack acts downstream of numb to specify distinct daughter cell fates during asymmetric cell divisions in the drosophila PNS

1995 • 110 citations

Developmental Signalling: Vertebrate ligands for Notch

1995 • 107 citations

Cell autonomy of expression of neurogenic genes of Drosophila melanogaster.

1987 • 107 citations

The determination of sense organs in Drosophila: effect of the neurogenic mutations in the embryo

1991 • 88 citations

Hairless, a Drosophila gene involved in neural development, encodes a novel, serine rich protein

1992 • 86 citations

Suppressor of Hairless is required for signal reception during lateral inhibition in the Drosophila pupal notum

1995 • 69 citations

Role of Notch and achaete-scute complex in the expression of Enhancer of split bHLH proteins

1995 • 61 citations

Invagination centers within the Drosophila stomatogastric nervous system anlage are positioned by Notch-mediated signaling which is spatially controlled through wingless

1995 • 59 citations

A perfect vulva every time: Gradients and signaling cascades in C. elegans

1995 • 58 citations

Cell fate patterning during C. elegans vulval development

1993 • 25 citations

Notch and Wingless Signals Collide

1996 • 25 citations

Genetic mechanisms of early neurogenesis in Drosophila melanogaster

1994 • 12 citations

A dual role for the protein kinase shaggy in the repression of achaete- scute

1993 • 11 citations

Cell fate choice during early neurogenesis in Drosophila melanogaster.

1994 • 6 citations

Deleted Work

1955 • 0 citations