A Role of Basic Residues and the Putative Intercalating Phenylalanine of the HMG-1 Box B in DNA Supercoiling and Binding to Four-way DNA Junctions

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

HMG domain proteins: architectural elements in the assembly of nucleoprotein structures

1994 • 813 citations

High-Mobility-Group Chromosomal Proteins: Architectural Components That Facilitate Chromatin Function

1996 • 752 citations

Specific Recognition of Cruciform DNA by Nuclear Protein HMG1

1989 • 596 citations

Structural basis for DNA bending by the architectural transcription factor LEF-1

1995 • 574 citations

Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins

1999 • 553 citations

Specific Binding of Chromosomal Protein HMG1 to DNA Damaged by the Anticancer Drug Cisplatin

1992 • 492 citations

DNA Binding Activity of Recombinant SRY from Normal Males and XY Females

1992 • 454 citations

Structure of the HMG box motif in the B-domain of HMG1.

1993 • 403 citations

High-Mobility Group Chromatin Proteins 1 and 2 Functionally Interact with Steroid Hormone Receptors To Enhance Their DNA Binding In Vitro and Transcriptional Activity in Mammalian Cells

1998 • 338 citations

The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures.

1993 • 327 citations

RAG1 and RAG2 Form a Stable Postcleavage Synaptic Complex with DNA Containing Signal Ends in V(D)J Recombination

1997 • 297 citations

Solution structure of a DNA-binding domain from HMG1

1993 • 275 citations

DNA-binding properties of the HMG domain of the lymphoid-specific transcriptional regulator LEF-1.

1991 • 265 citations

The DNA binding site of HMG1 protein is composed of two similar segments (HMG boxes), both of which have counterparts in other eukaryotic regulatory proteins.

1992 • 259 citations

Nonhistone Proteins HMG ₁ and HMG ₂ Change the DNA Helical Structure

1978 • 243 citations

High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors.

1995 • 224 citations

Short-Range DNA Looping by the Xenopus HMG-Box Transcription Factor, xUBF

1994 • 216 citations

High-mobility-group 1 protein mediates DNA bending as determined by ring closures.

1993 • 193 citations

The structure of a chromosomal high mobility group protein-DNA complex reveals sequence-neutral mechanisms important for non-sequence-specific DNA recognition

1999 • 193 citations

Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding

1999 • 173 citations

Structure of the A-Domain of HMG1 and Its Interaction with DNA as Studied by Heteronuclear Three- and Four-Dimensional NMR Spectroscopy

1995 • 166 citations

The Structure of the Four-Way Junction in DNA

1993 • 160 citations

DNA looping by the HMG-box domains of HMG1 and modulation of DNA binding by the acidic C-terminal domain

1994 • 139 citations

DNA Bending by the Chromosomal Protein HMG1 and Its High Mobility Group Box Domains

1998 • 108 citations

The specific interactions of HMG 1 and 2 with negatively supercoiled DNA are modulated by their acidic C-terminal domains and involve cysteine residues in their HMG 1/2 boxes

1993 • 107 citations

The solution structure and dynamics of the DNA-binding domain of HMG-D from Drosophila melanogaster

1994 • 100 citations

Proteins that specifically recognize cisplatin‐damaged DNA: a clue to anticancer activity of cisplatin

1998 • 99 citations

HMG box proteins bind to four-way DNA junctions in their open conformation

1998 • 96 citations

Competition between HMG-I(Y), HMG-1 and histone H1 on four-way junction DNA

1997 • 94 citations

Differences in the DNA‐Binding Properties of the Hmg‐Box Domains of HMG1 and the Sex‐Determining Factor SRY

1995 • 93 citations

Structure-specific binding of the two tandem HMG boxes of HMG1 to four-way junction DNA is mediated by the A domain

1999 • 92 citations

Tumor suppressor protein p53 binds preferentially to supercoiled DNA

1997 • 83 citations

Directional binding of HMG-I(Y) on four-way junction DNA and the molecular basis for competitive binding with HMG-1 and histone H1

1999 • 81 citations

Determinants of DNA Binding and Bending by theSaccharomyces cerevisiae High Mobility Group Protein NHP6A That Are Important for Its Biological Activities

1998 • 74 citations

Differences in the DNA-Binding Properties of the Hmg-Box Domains of HMG1 and the Sex-Determining Factor SRY

1995 • 71 citations

The DNA sequence specificity of HMG boxes lies in the minor wing of the structure.

1994 • 70 citations

Torsional Rigidity of Positively and Negatively Supercoiled DNA

1992 • 68 citations

xUBF, an RNA polymerase I transcription factor, binds crossover DNA with low sequence specificity.

1994 • 66 citations

NMR Spectroscopic Analysis of the DNA Conformation Induced by the Human Testis Determining Factor SRY

1995 • 61 citations

High mobility group protein 1 preferentially conserves torsion in negatively supercoiled DNA

1989 • 61 citations

HMG1 protein stimulates DNA end joining by promoting association of DNA molecules via their ends

2000 • 54 citations

Two mutations in the HMG-box with very different structural consequences provide insights into the nature of binding to four-way junction DNA.

1995 • 51 citations

Mutational analysis of the DNA binding domain A of chromosomal protein HMG1

1994 • 48 citations

The Structure of the HMG Box and Its Interaction with DNA

1995 • 39 citations

Calcium binding to HMG1 protein induces DNA looping by the HMG‐box domains

1994 • 38 citations

Formation of large nucleoprotein complexes upon binding of the high‐mobility‐group (HMG) box B‐domain of HMG1 protein to supercoiled DNA

1998 • 37 citations

Domain–domain interactions in high mobility group 1 protein (HMG1)

1999 • 32 citations

Homology model building of the HMG-1 box structural domain

1995 • 30 citations

Histone H1 preferentially binds to superhelical DNA molecules of higher compaction

1997 • 30 citations

The mechanism of sequence non-specific DNA binding of HMG1/2-box B in HMG1 with DNA

1999 • 17 citations

cDNA sequence and structure of a gene encoding trout testis high‐mobility‐group‐1 protein

1994 • 16 citations

Region of insect high mobility group (HMG) 1 protein homologous to helix 2 of the rat HMG1-b box is in close contact with DNA.

1994 • 11 citations

Analysis of HMG protein binding to DNA modified with the anticancer drug cisplatin

1996 • 6 citations