Proteins that specifically recognize cisplatin‐damaged DNA: a clue to anticancer activity of cisplatin

Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode

1965 • 2,890 citations

Cisplatin

1984 • 942 citations

Structural aspects of platinum anticancer drug interactions with DNA

1987 • 927 citations

HMG domain proteins: architectural elements in the assembly of nucleoprotein structures

1994 • 813 citations

High-Mobility-Group Chromosomal Proteins: Architectural Components That Facilitate Chromatin Function

1996 • 752 citations

Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin

1995 • 742 citations

Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair.

1994 • 646 citations

Specific Binding of Chromosomal Protein HMG1 to DNA Damaged by the Anticancer Drug Cisplatin

1992 • 492 citations

Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.

1996 • 422 citations

Xeroderma Pigmentosum Group E Cells Lack a Nuclear Factor That Binds to Damaged DNA

1988 • 417 citations

DNA adducts : identification and biological significance

1994 • 401 citations

HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease.

1994 • 343 citations

Repair of Cisplatin−DNA Adducts by the Mammalian Excision Nuclease

1996 • 335 citations

ERCC1 and ERCC2 Expression in Malignant Tissues From Ovarian Cancer Patients

1992 • 302 citations

Solution Structure of a Cisplatin-Induced DNA Interstrand Cross-Link

1995 • 300 citations

Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA

1993 • 295 citations

DNA unwinding produced by site-specific intrastrand crosslinks of the antitumor drug cis-diamminedichloroplatinum(II)

1991 • 289 citations

A signature for the HMG‐1 box DNA‐binding proteins

1993 • 258 citations

Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin.

1992 • 246 citations

Influence of cis-diamminedichloroplatinum(II) on DNA synthesis and cell cycle progression in excision repair proficient and deficient Chinese hamster ovary cells.

1988 • 226 citations

Structure and Isomerization of an Intrastrand Cisplatin-Cross-Linked Octamer DNA Duplex by NMR Analysis

1995 • 221 citations

The mismatch-repair protein hMSH2 binds selectively to DNA adducts of the anticancer drug cisplatin

1996 • 198 citations

Ixr1, a Yeast Protein That Binds to Platinated DNA and Confers Sensitivity to Cisplatin

1993 • 177 citations

The XPA protein is a zinc metalloprotein with an ability to recognize various kinds of DNA damage

1994 • 155 citations

Cisplatin-DNA adducts are molecular decoys for the ribosomal RNA transcription factor hUBF (human upstream binding factor).

1994 • 149 citations

Cisplatin-resistant cells express increased levels of a factor that recognizes damaged DNA.

1990 • 143 citations

Characterization of a DNA damage-recognition protein from mammalian cells that binds specifically to intrastrand d(GpG) and d(ApG) DNA adducts of the anticancer drug cisplatin

1990 • 133 citations

Mechanisms and modulation of resistance to chemotherapy in ovarian cancer

1993 • 113 citations

Binding to four‐way junction DNA: a common property of architectural proteins?

1998 • 106 citations

Identification of a damaged-DNA binding domain of the XPA protein

1996 • 106 citations

The HMG-domain protein Ixr1 blocks excision repair of cisplatin-DNA adducts in yeast

1996 • 103 citations

Isolation of cDNAs encoding a human protein that binds selectively to DNA modified by the anticancer drug cis-diamminedichloroplatinum(II)

1989 • 102 citations

DNA Adducts of cis-Diamminedichloroplatinum(II) and Its Trans Isomer Inhibit RNA Polymerase II Differentially in Vivo

1995 • 101 citations

The Linker Histones and Chromatin Structure: New Twists

1996 • 98 citations

HMG1-related DNA-binding protein isolated with V-(D)-J recombination signal probes.

1991 • 96 citations

Binding of human single-stranded DNA binding protein to DNA damaged by the anticancer drug cis-diamminedichloroplatinum (II).

1992 • 91 citations

HMG-D is an architecture-specific protein that preferentially binds to DNA containing the dinucleotide TG.

1995 • 90 citations

HMG Domain Proteins Induce Sharp Bends in Cisplatin-Modified DNA

1994 • 81 citations

NMR Solution Structure of a DNA Decamer Containing an Interstrand Cross-link of the Antitumor Drugcis-diamminedichloroplatinum(II)

1996 • 78 citations

DNA Sequence Context and Protein Composition Modulate HMG-Domain Protein Recognition of Cisplatin-Modified DNA

1997 • 76 citations

Human Ku Autoantigen Binds Cisplatin-damaged DNA but Fails to Stimulate Human DNA-activated Protein Kinase

1996 • 61 citations

Characterization of high mobility group protein binding to cisplatin-damaged DNA

1992 • 60 citations

The major chromatin protein histone H1 binds preferentially to cis -platinum-damaged DNA

1997 • 60 citations

A Single HMG Domain in High-Mobility Group 1 Protein Binds to DNAs as Small as 20 Base Pairs Containing the Major Cisplatin Adduct

1995 • 57 citations

Cisplatin inhibits chromatin remodeling, transcription factor binding, and transcription from the mouse mammary tumor virus promoter in vivo.

1995 • 55 citations

Photoreactivity of Platinum(II) in Cisplatin-Modified DNA Affords Specific Cross-Links to HMG Domain Proteins

1996 • 53 citations

A Novel Role for DNA Photolyase: Binding to DNA Damaged by Drugs Is Associated with Enhanced Cytotoxicity in Saccharomyces cerevisiae

1994 • 50 citations

The other function of DNA photolyase: stimulation of excision repair of chemical damage to DNA

1995 • 50 citations

Binding of Ixr1, a Yeast HMG-Domain Protein, to Cisplatin−DNA Adducts in Vitro and in Vivo

1996 • 48 citations

Interaction between Cisplatin-modified DNA and the HMG Boxes of HMG 1: DNase I Footprinting and Circular Dichroism

1995 • 44 citations

Isolation and characterization of cDNA clones encoding theDrosophilahomolog of the HMG-box SSRP family that recognizes specific DNA structures

1993 • 37 citations

Molecular Aspects of Platinum-DNA Interactions

1993 • 37 citations

T4 Endonuclease VII Cleaves DNA Containing a Cisplatin Adduct

1993 • 35 citations

Cisplatin−DNA Binding Specificity of Calf High-Mobility Group 1 Protein

1996 • 33 citations

A novel role for DNA photolyase: binding to DNA damaged by drugs is associated with enhanced cytotoxicity in Saccharomyces cerevisiae.

1994 • 33 citations

DNA adducts of cisplatin, transplatin and platinum-intercalating drugs.

1994 • 27 citations

Salvage therapy for germ cell tumors.

1994 • 26 citations

Induction of UV-Damage Recognition Protein by Cisplatin Treatment

1995 • 25 citations

Cisplatin adducts in DNA: distortion and recognition

1996 • 22 citations

Chromatin architectural proteins and transcription factors: A structural connection

1996 • 18 citations

Localization of the binding region of high mobility group protein 2 to cisplatin-damaged DNA.

1993 • 17 citations

Platinum compounds in cervical and endometrial cancers: focus on carboplatin.

1994 • 9 citations

Cisplatin-induced alterations in the expression of the mRNAs for UV-damage recognition protein.

1996 • 5 citations